Locator® versus ceramic/electroplated double-crown attachments: a prospective study on the intraindividual comparison of implant-supported mandibular prostheses

Clinical Oral Investigations - Implant-supported overdentures are an established dental treatment mode. The aim of this prospective study was and interindividual comparison of patient satisfaction...     

Performance Evaluation of Medical Records Departments by Analytical Hierarchy Process (AHP) Approach in the Selected Hospitals in Isfahan

Medical Records Department (MRD) is an important unit for evaluating and planning of care services. The goal of this study is evaluating the performance of the Medical Records Departments (MRDs) of the selected hospitals in Isfahan, Iran by using Analytical Hierarchy Process (AHP). This was an analytic of cross-sectional study that was done in spring 2008 in Isfahan, Iran. The statistical population consisted of MRDs of Alzahra, Kashani and Khorshid Hospitals in Isfahan. Data were collected by forms and through brainstorm technique. To analyze and perform AHP, Expert Choice software was used by researchers. Results were showed archiving unit has received the largest importance weight with respect to information management. However, on customer aspect admission unit has received the largest weight. Ordering weights of Medical Records Departments’ Alzahra, Kashani and Khorshid Hospitals in Isfahan were with 0.394, 0.342 and 0.264 respectively. It is useful for managers to allocate and prioritize resources according to AHP technique for ranking at the Medical Records Departments.     

Aetiological studies of diarrhoeal diseases in infants and young children in Iran

The aetiology of diarrhoeal diseases was investigated among 715 patients admitted to four Children's Hospitals in Tehran, during February 1986 to March 1987, and also among 443 patients attending the central Out-Patient Clinic in Sanandaj, State of Kordestan, during October 1986. Enteropathogenic Escherichia coli (EPEC) were the most common pathogens found in both areas. Almost 26.7% of the patients in Tehran and 20.1% of the patients in Sanandaj were infected with EPEC. Enterotoxigenic E. coli (ETEC) were the next most frequent groups found (17.1% both in Tehran and Sanandaj), with heat-stable enterotoxin (ST)-producing strains being dominant. Of 122 ETEC strains isolated in Tehran, 94 (77%) strains produced ST, 15 (12.3%) strains produced heat-labile enterotoxin (LT) and 13 (10.7%) strains produced both LT and ST. Almost the same pattern of toxigenicity was observed among ETEC strains isolated in Sanadaj. Of the 76 ETEC strains isolated in this area, 70 (92.1%) strains were ST producers, followed by those producing both LT and ST (five strains) and LT only (one strain). One strain of enteroinvasive E. coli (EIEC) was also isolated from a patient in Tehran. The rates of salmonella and shigella isolation were 8.8 and 5.7% in Tehran and 3.8 and 4% in Sanandaj respectively. Enterohaemorrhagic E. coli, Vibrio cholerae and V. parahemolyticus were not isolated but a mixture of two or more pathogens was found in 59 patients (8.2%) in Tehran and in 20 patients (4.5%) in Sanandaj. These findings suggest that diarrhoegenic E. coli are the most important cause of diarrhoeal diseases in infants and young children in these areas in Iran.     

Distinct gene expression profiles in ovarian cancer linked to Lynch syndrome

Ovarian cancer linked to Lynch syndrome represents a rare subset that typically presents at young age as early-stage tumors with an overrepresentation of endometrioid and clear cell histologies. We investigated the molecular profiles of Lynch syndrome-associated and sporadic ovarian cancer with the aim to identify key discriminators and central tumorigenic mechanisms in hereditary ovarian cancer. Global gene expression profiling using whole-genome c-DNA-mediated Annealing, Selection, extension, and Ligation was applied to 48 histopathologically matched Lynch syndrome-associated and sporadic ovarian cancers. Lynch syndrome-associated and sporadic ovarian cancers differed by 349 significantly deregulated genes, including PTPRH, BIRC3, SHH and TNFRSF6B. The genes involved were predominantly linked to cell growth, proliferation, and cell-to-cell signaling and interaction. When stratified for histologic subtype, hierarchical clustering confirmed distinct differences related to heredity in the endometrioid and serous subtypes. Furthermore, separate clustering was achieved in an independent, publically available data set. The distinct genetic signatures in Lynch syndrome-associated and sporadic ovarian cancers point to alternative preferred tumorigenic routes and suggest that genetic discriminators may be relevant for molecular diagnostics and targeted therapeutics.     

Thyroid-associated ophthalmopathy in Iranian patients

We determined the frequency of clinical thyroid ophthalmopathy in Iranian patients. This cross-sectional study was performed at the Endocrinology Institute of Tehran University of Medical Sciences. All patients with documented thyroid disorders from September 2003 to July 2005 were recruited. Eye examinations included evaluation of soft tissue changes, measurement of proptosis, lid width, lagophthalmos, evaluation of eye muscle function, and determination of visual acuity. The activity of ophthalmopathy was scored according to the NOSPECS scale. Among 851 visited patients, 303 cases had thyroid eye disease (TED). The nature of the ophthalmopathy breaks down as follows: 53.4% were hypothyroid (9.3% Hashimoto disease), 5.5% euthyroid and 41.1% had Graves' disease. The prevalence of TED in males was 60% which was nearly 2 times the prevalence of TED in females. There was a significant relationship between presentation of TED and active smoking of the patients (P<0.0001) while no significant relationship with passive smoking was obtained (P=0.181). The most common clinical sign of TED in descending order respectively were proptosis with 63.4%, soft tissue involvement (40.9%), extraocular muscle involvement (22.1%), corneal involvement (12.9%) and optic nerve dysfunction (6.3%). Myasthenia gravis occurred in only 2 patients. In the logistic regression, occurrence of TED was influenced by cardiovascular disease (OR=5.346), Graves' disease (OR=47.507), radioiodine therapy (OR=2.590), and anti-thyroid medications (OR=0.650). Thyroid ophtalmopathy (orbitopathy) is a matter of important health concern among patients with thyroid disorder. Since TED occurred with a high prevalence in all thyroid states, a close collaboration between endocrinologists and ophthalmologists along with timely referrals of patients with any eye complaint is deemed necessary. Also smoking was the most important risk factor for developing TED. Therefore, it is advisable to raise awareness and to strongly encourage smokers with thyroid disorders to quit smoking.     

The effects of local anesthetic containing adrenaline on gingival blood flow in smokers and non smokers

Abstract Recent evidence suggests that fundamental differences exist in the development of gingival and periodontal diseases in smokers versus non-smokers. In part, these differences may be attributable to smoking-induced differences in the vascular dynamics of the periodontium. This study monitored gingival blood flow when challenged by a local anesthetic-containing adrenaline in 20 smokers and 20 non-smokers using laser Doppler flowmentry (LDF). The dosage of local anesthetic used (0.5 ml lignocaine hydrochloride 2% with adrenaline 1:80.000) was calculated after establishing a dose-response curve (DRC) for 3 subjects (2 non-smokers and 1 smoker). Plain lignocaine and normal saline were used as controls. The injection of lignocaine-containing adrenaline had little effect on LDF signals when different doses were injected at frequent short intervals, indicating that tolerance to adrenaline had rapidly developed in the receptors of gingival blood vessels. Injection of local anesthetics containing adrenaline consistently resulted in a marked and significant drop (average: 46%, sd:13.5) in the LDF output signals from gingiva; smokers and non-smokers responded similarly. The significant finding of this study was that the recovery of LDF signals to baseline took considerably longer in smokers than in non-smokers. This provides further evidence that gingival blood vessels in smokers with healthy gingival conditions respond differently to those of non-smokers.     

Thirteen-year follow-up study of resin-bonded fixed partial dentures.

OBJECTIVE: The technique of resin-bonded fixed partial dentures (RBFPD) is a well-accepted clinical technique to replace missing teeth. The survival rates reported in the literature vary widely, and the conclusions are sometimes conflicting. This study presents the clinical long-term performance of silicoated RBFPDs and also determines the main cause of failure. METHOD AND MATERIALS: Sixty-one patients with a total of 74 RBFPDs were either examined or requested to complete a questionnaire regarding their fixed partial dentures. Sixty-four were placed in the anterior region, and 10 in the posterior region. No more than one missing tooth in the posterior area and two missing teeth in the anterior region were replaced with RBFPDs. A retentive preparation was made on the abutment teeth. All the RBFPDs were adhesively seated. RESULTS: Eighteen RBFPDs failed after a mean observation time of 7.8 years (nine retention losses of one or more retainers, six carious lesions, and three veneer fractures occurred). Seven RBFPDs were rebonded, whereas the remaining 11 failures had to be replaced with conventional FPDs. Fifty-six RBFPDs were primary restorations, and seven secondary RBFPDs were used after the loss of the primary restoration. A mean survival rate better than 69% after a 13-year observation period was calculated. Including the rebonded restorations, a mean functional survival rate of 83% was estimated. A total of 18 failures (24.3%) of all restorations were observed, the main cause being loss of retention. CONCLUSION: Silicoated RBFPDs are a viable treatment means with an acceptable success expectancy.     

Adherence to confidentiality principles from the viewpoint of Iranian dental students: A multicenter study

Introduction

Confidentiality is a basic ethical principle appreciating human autonomy, relationships, and dignity and in medical research has a long history. In dental practice, it has the same importance as medical field. Therefore, providing patients with information about the confidentiality will promote their confidence in dental professionals and prevent legal conflicts. The present study sought to evaluate the knowledge and viewpoints of dental students about patient confidentiality.

Methods and Materials

In this multicenter applied research, the participants were recruited from schools of dentistry of Isfahan, Tehran, Tabriz, Shiraz, and Mashhad Universities of Medical Sciences and Isfahan Islamic Azad University during 2013. Ultimately, data were collected randomly with a researcher‐made questionnaire from 180 dental students of fifth‐sixth‐year. The collected data were entered into SPSS 20.0. Independent t‐tests and one‐way analysis of variance (ANOVA) were performed to analyze the data.

Result

Overall, 60.3% of the participating students were concerned about acquiring adequate knowledge on the concept of patient confidentiality and 59.0% felt obliged to participate in related educational courses. Most students (66.5%) were careful not to share patient information with their friends. According to one‐way ANOVA, students of Tehran University of Medical Sciences scored significantly higher than other participants. However, no significant differences were detected between the students of other schools.

Conclusion

The confidentiality laws imposed by the Ministry of Health and Medical Education seem to adequate details, but needs more education for dentists. Also it should be accentuated, due to state of confidentiality in patients’ rights guidline and courses on ethics should be tailored based on the specific subjects raised in each field of dentistry.