全文获取类型
收费全文 | 8108篇 |
免费 | 1427篇 |
国内免费 | 23篇 |
专业分类
耳鼻咽喉 | 196篇 |
儿科学 | 46篇 |
妇产科学 | 31篇 |
基础医学 | 256篇 |
口腔科学 | 6804篇 |
临床医学 | 242篇 |
内科学 | 451篇 |
皮肤病学 | 95篇 |
神经病学 | 162篇 |
特种医学 | 34篇 |
外国民族医学 | 1篇 |
外科学 | 599篇 |
综合类 | 13篇 |
预防医学 | 282篇 |
眼科学 | 46篇 |
药学 | 157篇 |
中国医学 | 13篇 |
肿瘤学 | 130篇 |
出版年
2024年 | 28篇 |
2023年 | 353篇 |
2022年 | 40篇 |
2021年 | 86篇 |
2020年 | 149篇 |
2019年 | 87篇 |
2018年 | 307篇 |
2017年 | 370篇 |
2016年 | 416篇 |
2015年 | 506篇 |
2014年 | 537篇 |
2013年 | 529篇 |
2012年 | 364篇 |
2011年 | 355篇 |
2010年 | 408篇 |
2009年 | 579篇 |
2008年 | 306篇 |
2007年 | 268篇 |
2006年 | 244篇 |
2005年 | 193篇 |
2004年 | 178篇 |
2003年 | 218篇 |
2002年 | 186篇 |
2001年 | 207篇 |
2000年 | 191篇 |
1999年 | 202篇 |
1998年 | 246篇 |
1997年 | 211篇 |
1996年 | 204篇 |
1995年 | 181篇 |
1994年 | 180篇 |
1993年 | 132篇 |
1992年 | 155篇 |
1991年 | 91篇 |
1990年 | 102篇 |
1989年 | 64篇 |
1988年 | 94篇 |
1987年 | 88篇 |
1986年 | 45篇 |
1985年 | 71篇 |
1984年 | 71篇 |
1983年 | 63篇 |
1982年 | 57篇 |
1981年 | 35篇 |
1979年 | 15篇 |
1978年 | 15篇 |
1977年 | 15篇 |
1976年 | 15篇 |
1975年 | 20篇 |
1974年 | 17篇 |
排序方式: 共有9558条查询结果,搜索用时 15 毫秒
1.
Mark Koday DDS Stephen Davis DDS Molly Melbye DDS MPH 《Journal of public health dentistry》2020,80(Z2):S114-S116
The Yakima Valley Farm Workers Clinic (YVFWC) is one of the largest community health centers in the country with clinics throughout south-central Washington and northern Oregon. Its dental program consists of 14 dental clinics providing general and specialty services to the low-income populations it serves. Modeling itself after the YVFWC medical managed care program; the Dental program recently added value-based metrics to its dental practice after Oregon offered a value-based dental reimbursement plan in 2019. This is the first-step YVFWC's dental program that has taken to prepare for value-based reimbursement and transform its dental practice in order to reduce the disease burden in its patient population. The purpose of this article is to describe the processes YVFWC undertook to prepare itself for the new reimbursement model, which included the development of metrics, a metric validation process, a clinical dashboard, and a method for improving metrics. It also outlines its medical/dental integration improvement brought about by embedding hygienists into the medical primary care teams. 相似文献
2.
The Transient Receptor Potential Vanilloid 1 Antagonist Capsazepine Improves the Impaired Lung Mechanics during Endotoxemia
下载免费PDF全文
![点击此处可从《Basic & clinical pharmacology & toxicology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Layla D. M. Cabral Alexandre Giusti‐Paiva 《Basic & clinical pharmacology & toxicology》2016,119(5):421-427
Acute lung injury (ALI) caused by systemic inflammatory response remains a leading cause of morbidity and mortality in critically ill patients. Management of patients with sepsis is largely limited to supportive therapies, reflecting an incomplete understanding of the underlying pathophysiology. Furthermore, there have been limited advances in the treatments for ALI. In this study, lung function and a histological analysis were performed to evaluate the impact of transient receptor potential vanilloid‐1 receptor (TRPV1) antagonist (capsazepine; CPZ) on the lipopolysaccharide (LPS)‐induced lung injury in mice. For this, adult mice pre‐treated with CPZ or vehicle received intraperitoneal injections of LPS or saline and 24 hr after, the mice were anaesthetized, and lung mechanics was evaluated. The LPS‐challenged mice exhibited substantial mechanical impairment, characterized by increases in respiratory system resistance, respiratory system elastance, tissue damping and tissue elastance. The pre‐treatment with CPZ prevented the increase in respiratory system resistance and decreased the increase in tissue damping during endotoxemia. In addition, mice pre‐treated with CPZ had an attenuated lung injury evidenced by reduction on collapsed area of the lung parenchyma induced by LPS. This suggests that the TRPV1 antagonist capsazepine has a protective effect on lung mechanics in ALI during endotoxemia and that it may be a target for enhanced therapeutic efficacy in ALI. 相似文献
3.
4.
John Lennon Silva Cunha Amanda Almeida Leite Thamiris de Castro Abrantes Lorena Passoni Vervloet Thayn Melo de Lima Morais Gerson de Oliveira Paiva Neto Tatiana Nayara Librio Kimura Snia Maria Soares Ferreira Ricardo Luiz Cavalcanti de Albuquerque‐Júnior Aline Corrêa Abraho Mario Jos Romaach Bruno Augusto Benevenuto de Andrade Oslei Paes de Almeida Ciro Dantas Soares 《Journal of cutaneous pathology》2021,48(1):24-33
5.
6.
Thaís dos Santos Fontes Pereira Carolina Cavalieri Gomes Peter A Brennan Felipe Paiva Fonseca Ricardo Santiago Gomez 《Journal of oral pathology & medicine》2019,48(1):3-9
Fibrous dysplasia is a non‐neoplastic developmental process that affects the craniofacial bones, characterized by painless enlargement as a result of bone substitution by abnormal fibrous tissue. Postzygotic somatic activating mutations in the GNAS1 gene cause fibrous dysplasia and have been extensively investigated, as well as being helpful in the differential diagnosis of the disease. Fibrous dysplasia may involve one (monostotic) or multiple bones (polyostotic), sporadically or in association with McCune‐Albright syndrome, Jeffe‐Lichenstein syndrome, or Mazabreud syndrome. This review summarizes the current knowledge on fibrous dysplasia, emphasizing the value of integrating the understanding of its molecular pathogenesis with the clinical, radiological, and histopathological features. In addition, we address important aspects related to the differential diagnosis and patient management. 相似文献
7.
de Oliveira Adilson J M Solla Davi J. F. de Oliveira Klever F. Amaral Bruno S. Andrade Almir F. Kolias Angelos G. Paiva Wellingson S. 《Neurological sciences》2022,43(1):427-434
Neurological Sciences - Chronic subdural haematoma (CSDH) is one of the most common neurosurgical pathologies. The recurrence of chronic subdural haematomas is an important concern, considering... 相似文献
8.
Reem Haj-Ali BDS DDS MS ; Mary Walker DDS PhD ; Karen Williams PhD ; Yong Wang PhD ; Paulette Spencer DDS PhD 《Journal of prosthodontics》2006,15(2):82-88
PURPOSE: The purpose of this study was to compare the dentin/adhesive interfacial characteristics when bonding to noncarious as well as caries-affected dentin. MATERIALS AND METHODS: Seven extracted, unerupted, third molars were sectioned into halves. Artificial caries was created on one-half of each tooth, leaving the other half as a control. Dentin surfaces were treated with UNO adhesive according to the manufacturer's instructions for the wet-bonding technique and under environmental conditions present in the oral cavity. Dentin/adhesive interface sections of each half-tooth were stained with Goldner's trichrome, a classic bone stain, and examined using light microscopy. The width of exposed collagen was measured directly from photomicrographs, and adhesive penetration was analyzed qualitatively. RESULTS: The degree and extent to which the adhesive encapsulated the demineralized dentin matrix were reflected in the color difference in the stained sections with the noncarious dentin sections showing a degree of collagen encapsulation superior to that of the caries-affected dentin sections. The overall mean widths of exposed collagen were significantly (p < or = .05) greater at the caries-affected dentin/adhesive interface, 8.6 (1.7) microm, as compared with those at the noncarious dentin/adhesive interface, 6.0 (1.5) microm. CONCLUSIONS: The morphologic characteristics of the caries-affected dentin/interface suggest an increase in the exposed collagen zone and a decrease in the quality of the adhesive infiltration when compared with noncarious dentin. The evidence suggests that dentin substrate characteristics have a significant effect on the dentin/adhesive interface structure. 相似文献
9.
The intention of this article is to introduce the reader to the Transograph from a historical perspective. The technical data presented are intended to help the reader understand the design of this unique instrument and how it was programmed, but will not provide the reader a thorough understanding of this philosophy. The article seeks neither to defend nor criticize the principles of Transographics. 相似文献
10.