全文获取类型
收费全文 | 221901篇 |
免费 | 5542篇 |
国内免费 | 561篇 |
专业分类
耳鼻咽喉 | 3129篇 |
儿科学 | 8033篇 |
妇产科学 | 6433篇 |
基础医学 | 28706篇 |
口腔科学 | 7874篇 |
临床医学 | 16927篇 |
内科学 | 41578篇 |
皮肤病学 | 5033篇 |
神经病学 | 13987篇 |
特种医学 | 11117篇 |
外国民族医学 | 97篇 |
外科学 | 33058篇 |
综合类 | 1312篇 |
一般理论 | 10篇 |
预防医学 | 18743篇 |
眼科学 | 4919篇 |
药学 | 15157篇 |
2篇 | |
中国医学 | 291篇 |
肿瘤学 | 11598篇 |
出版年
2021年 | 1137篇 |
2019年 | 899篇 |
2018年 | 4511篇 |
2017年 | 4503篇 |
2016年 | 3828篇 |
2015年 | 5597篇 |
2014年 | 5427篇 |
2013年 | 4747篇 |
2012年 | 12069篇 |
2011年 | 7093篇 |
2010年 | 3443篇 |
2009年 | 4920篇 |
2008年 | 3952篇 |
2007年 | 4764篇 |
2006年 | 4739篇 |
2005年 | 12753篇 |
2004年 | 13984篇 |
2003年 | 9363篇 |
2002年 | 4536篇 |
2001年 | 4571篇 |
2000年 | 1884篇 |
1999年 | 6051篇 |
1992年 | 6984篇 |
1991年 | 7186篇 |
1990年 | 7423篇 |
1989年 | 7015篇 |
1988年 | 6530篇 |
1987年 | 6279篇 |
1986年 | 5996篇 |
1985年 | 5282篇 |
1984年 | 3639篇 |
1983年 | 2952篇 |
1982年 | 1060篇 |
1981年 | 814篇 |
1980年 | 864篇 |
1979年 | 3859篇 |
1978年 | 2390篇 |
1977年 | 1820篇 |
1976年 | 1583篇 |
1975年 | 2485篇 |
1974年 | 3124篇 |
1973年 | 2762篇 |
1972年 | 2771篇 |
1971年 | 2759篇 |
1970年 | 2564篇 |
1969年 | 2477篇 |
1968年 | 2245篇 |
1967年 | 2167篇 |
1966年 | 1910篇 |
1965年 | 1139篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
2.
3.
4.
Ruiz-Úcar Elena Acín-Gándara Débora Medina-García Manuel Ronda Diego Cruzado Pereira-Pérez Fernando 《Obesity surgery》2022,32(2):569-570
Obesity Surgery - Laparoscopic sleeve gastrectomy (LSG) is increasingly playing a key role in obesity management. Such operations, however, carry complications sometimes including leaks. The... 相似文献
5.
Alejandra Gordillo Hernández Eduardo Dominguez-Adame Lanuza Auxiliadora Cano Matias Rosario Perez Huertas Katherine Maria Gallardo Rodriguez Purificacion Gallinato Perez Fernando Oliva Mompean 《World journal of gastrointestinal surgery》2015,7(8):170-173
Gangliocytic paragangliomas are rare tumors that almost exclusively occur within the second portion of the duodenum. Although these tumors generally have a benign clinical course, they have the potential to recur or metastasize to regional lymph nodes. The case report presented here describes a 57-year-old female patient with melena, progressive asthenia, anemia, and a mass in the second-third portion of the duodenum that was treated by local excision. The patient was diagnosed with a friable bleeding tumor. The histologic analysis showed that the tumor was a 4 cm gangliocytic paraganglioma without a malignant cell pattern. In the absence of local invasion or distant metastasis, endoscopic resection represents a feasible, curative therapy. Although endoscopic polypectomy is currently considered the treatment of choice, it is not recommended if the size of the tumor is > 3 cm and/or there is active or recent bleeding. Patients diagnosed with a gangliocytic paraganglioma should be closely followed-up for possible local recurrence. 相似文献
6.
7.
8.
Attachment is a behavioral and physiological system, which enables individual’s dynamic adaptation to its environment. Attachment develops in close interaction between an infant and his/her mother, plays an important role in the development of the infant’s brain, and influences the quality of interpersonal relationships throughout life.Security of attachment is believed to influence individual response to stress, exposing insecurely organized individuals to deregulated autonomic nervous system and exaggerated hypothalamic-pituitary-adrenal activity, which, in turn, produces increased and prolonged exposure to stress-hormones. Such stress responses may have considerable implications for the development of diverse health-risk conditions, such as insulin resistance and hyperlipidemia, shown by numerous studies.Although the mechanisms are not yet fully understood, there is compelling evidence highlighting the role of psychological stress in the development of type 1 diabetes (T1D). One of the possible contributing factors for the development of T1D may be the influence of attachment security on individual stress reactivity. Thus, the suggestion is that insecurely attached individuals are more prone to experience increased and prolonged influence of stress hormones and other mechanisms causing pancreatic beta-cell destruction.The present paper opens with a short overview of the field of attachment in children, the principal attachment classifications and their historic development, describes the influence of attachment security on individual stress-reactivity and the role of the latter in the development of T1D. Following is a review of recent literature on the attachment in patients with T1D with a conclusion of a proposed role of attachment organization in the etiology of T1D. 相似文献
9.
Torbj?rn Karlsson 《Upsala journal of medical sciences》2015,120(4):257-262
Background. Haemophagocytic lymphohistiocytosis (HLH) is a rare clinical syndrome characterized by fever, hepatosplenomegaly, cytopenia, and progressive multiple-organ failure. HLH in adults is often secondary to autoimmune diseases, cancer, or infections in contrast to familial HLH. Treatment of secondary HLH is directed against the triggering disease in addition to immunosuppressive therapy, the latter commonly according to the HLH-2004 protocol.Methods. We conducted a retrospective study to identify triggering diseases, disease-specific and immunosuppressive therapy administered, and prognosis in adult patients with secondary HLH. Patient data were collected from October 2010 to January 2015.Results. Ten adult patients with secondary HLH were identified. Seven were men, and the median age at diagnosis was 62 years. Five cases were triggered by malignant disease and five by infection. The median patient fulfilled five of the eight HLH-2004 diagnostic criteria. All patients fulfilled the criteria fever, cytopenia, and ferritin >500 µg/L. Median time from hospital admission to HLH diagnosis was 20 days. Four patients received immunosuppressive therapy according to the HLH-2004 protocol. The prognosis was dismal, especially for the patients with malignancy-associated HLH, of whom all died.Conclusion. HLH should be suspected in patients who present with fever, cytopenia, and ferritin >500 µg/L. Secondary HLH has a dismal prognosis. None of the patients with HLH triggered by malignancy survived. Achieving remission of the triggering disease seems to be important for a favourable outcome as, in all surviving patients, the haemophagocytic syndrome resolved after remission of the underlying infection. 相似文献