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Zufan Yegezu Lea Mollon Dhafer Mahdi Alshayban Jawad Bilal Sandipan Bhattacharjee 《Research in social & administrative pharmacy》2021,17(2):307-314
BackgroundAccording to the American College of Cardiology/the American Heart Association (ACC/AHA) recommendations, health-related risk behaviors for secondary prevention of myocardial infarction (MI) are critical to determine.ObjectiveThis study aimed to compare health-related risk behaviors between MI survivors and propensity-score-matched non-MI controls using nationally representative data.MethodsThis cross-sectional, matched case-control study used publicly available Behavioral Risk Factor Surveillance System (BRFSS) 2017 data. Older adults with MI were propensity-score-matched to their non-MI controls. The 10 dependent variables included body mass index (BMI), smoking status, heavy alcohol consumption, influenza vaccine, length of time since last routine and cholesterol checkup, alcohol consumption, fruit and vegetable consumption, and physical activity. Chi-square tests and binomial logistic regression were used to examine the health-related risk behaviors differences between MI survivors and propensity-score-matched non-MI controls.ResultsThe final study sample consisted of 18,021 MI survivors and 54,063 non-MI controls after propensity score matching. Multivariable logistic regression analysis showed significant differences between MI survivors and matched non-MI controls in terms of cholesterol checkup, smoking status, and alcohol consumption. For example, multivariate analysis of health-related risk behaviors showed MI survivors were more likely to be smokers (AOR = 1.46, 95% CI: 1.28–1.68).ConclusionBased on this national survey of adults, MI survivors were more likely to be smokers but less likely to consume alcohol compared to their propensity-score-matched controls. Moreover, MI survivors were more likely to have their cholesterol checkup within the past 2 years compared to matched non-MI controls. Although lower alcohol consumption and greater chances of cholesterol checkups are reassuring health-related behaviors, interventions are needed to minimize the chances of smoking in this population. 相似文献
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James C. Melville Christopher Scott Manis Jonathan W. Shum Dhafer Alsuwied 《Journal of oral and maxillofacial surgery》2019,77(4):874.e1-874.e13
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Dhafer S. Zinad Ahmed Mahal Ranjan K. Mohapatra Ashish K. Sarangi Mohammad Rizki Fadhil Pratama 《Chemical biology & drug design》2020,95(1):16-47
Oxazines have brought much synthetic interest due to their extensive biological activities. These are the important category of heterocycles, which may be formally derived from benzene and its reduction products by convenient substitution of carbon (and hydrogen) atoms by nitrogen and oxygen. In the last few decades, oxazine derivatives have documented as worthy synthetic intermediates and also blessed with notable sedative, analgesic, anticonvulsant, antipyretic, antimicrobial, antitubercular, antimalarial, antioxidant, and anticancer activities. Nowadays, it is important to develop new classes of compounds with more effective mechanisms due to drug resistance activity in which the ability of drug to effectively treat disease can be reduced. The aim of the article is to collect and make a more generalized review on the synthesis of oxazine derivatives and their pharmaceutical and biological activities. We hope this review will provide ample references for the researchers concerned with azines in generally and oxazines in particular. 相似文献
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Imen Aissa Rabiaa Manel Sghair Mohamed Bouaziz Dhafer Laouini Sami Sayadi Youssef Gargouri 《Lipids in health and disease》2012,11(1):13
Background
Preparation of tyrosyl lipophilic derivatives was carried out as a response to the food, cosmetic and pharmaceutical industries' increasing demand for new lipophilic antioxidants. 相似文献8.
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Ahmed Mahal Meitao Duan Dhafer S. Zinad Ranjan K. Mohapatra Ahmad J. Obaidullah Xiaoyi Wei Manoj K. Pradhan Debadutta Das Venkataramana Kandi Hany S. Zinad Quanhong Zhu 《RSC advances》2021,11(3):1804
Influenza virus is the main cause of an infectious disease called influenza affecting the respiratory system including the throat, nose and lungs. Neuraminidase inhibitors are reagents used to block the enzyme called neuraminidase to prevent the influenza infection from spreading. Neuraminidase inhibitors are widely used in the treatment of influenza infection, but still there is a need to develop more potent agents for the more effective treatment of influenza. Complications of the influenza disease lead to death, and one of these complications is drug resistance; hence, there is an urgent need to develop more effective agents. This review focuses on the recent advances in chemical synthesis pathways used for the development of new neuraminidase agents along with the medicinal aspects of chemically modified molecules, including the structure–activity relationship, which provides further rational designs of more active small molecules.Influenza virus is the main cause of an infectious disease called influenza affecting the respiratory system including the throat, nose and lungs. 相似文献