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Tanise Vendruscolo Dalmolin Andreza Francisco Martins Alexandre Prehn Zavascki Daiana de Lima-Morales Afonso Luís Barth 《Diagnostic microbiology and infectious disease》2018,90(2):132-133
We identified one clinical isolate of K. pneumoniae harboring the mcr 1 (plasmid of IncX4 family) and blaKPC-2 (plasmid of IncFIB family) genes in southern Brazil. These findings highlight that K. pneumoniae isolates carrying both mcr-1 and blaKPC-2 may emergence as a serious threat to antimicrobial therapy. 相似文献
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Francisco Alburquerque-Sendín Angelica Viana Ferrari Daiana Priscila Rodrigues-de-Souza Paula Paras-Bravo Juan Francisco Velarde-García Domingo Palacios-Ceña 《Nursing outlook》2018,66(3):293-310
Purpose
The purpose of the study was to summarize the experiences of African psychiatric nurses in their workplace by examining the findings of existing qualitative studies.Methods
Eleven studies published in English, Portuguese, and Spanish, between 1998 and 2016, which explored psychiatric nurses' experiences in Africa, were included.Findings
After meta-aggregation, five key findings were identified: 1) organization and management, 2) perceptions of professional safety and insecurity, 3) relationship with the patient, 4) emotional experiences and 5) recommendations for improvement.Discussion
The findings in this study highlight the stressful nature of the work climate of the psychiatric nurse in South Africa. More focus on improving working conditions and providing support is necessary to increase the quality of care for psychiatric mental health patients and their nurse providers. 相似文献5.
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Kurtz M Martínez N Capobianco E Higa R Fornes D White V Jawerbaum A 《Molecular and cellular endocrinology》2012,362(1-2):120-127
The fetal lung is affected by maternal diabetes. Nuclear receptor PPARα regulates nitric oxide (NO) overproduction in different tissues. We aimed to determine whether fetal lung PPARα expression is altered by maternal diabetes, and if there are gender-dependent changes in PPARα regulation of NO production in the fetal lung. Fetal lungs from control and diabetic rats were explanted on day 21 of gestation and evaluated for PPARα expression and NO production. Fetuses were injected with the PPARα ligand LTB(4) on days 19, 20 and 21, and the fetal lung explanted on day 21 to evaluate PPARα and the inducible isoform of NO synthase (iNOS). Besides, pregnant rats were fed with olive oil- and safflower oil-supplemented diets, enriched in PPAR ligands, for evaluation of fetal lung NO production and PPARα expression. We found reduced PPARα concentrations only in the lung from male fetuses from the diabetic group when compared to controls, although maternal diabetes led to NO overproduction in both male and female fetal lungs. Fetal activation of PPARα led to changes in lung PPARα expression only in female fetuses, although this treatment increased iNOS expression in both male and female fetuses in the diabetic group. Diets supplemented with olive oil and not with safflower oil led to a reduction in NO production in male and female fetal lungs. In conclusion, there are gender-dependent changes in PPARα expression and signaling in the fetal lung from diabetic rats, although PPARα activation prevents maternal diabetes-induced lung NO overproduction in both male and female fetuses. 相似文献
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