唇腭裂患者的贫血状况研究

目的:了解唇腭裂患者的贫血状况,分析影响其贫血率的因素,为采取有效措施预防其发生贫血提供依据?方法:对2007年1月至2008年11月期间,在南京医科大学附属口腔医院治疗的346例唇腭裂患者进行调查统计分析,同时跟踪调查唇腭裂各项修复均在该院进行的12例患者修复前后红细胞(rbc)和血红蛋白(hgb)的变化?结果:将346例患者按畸型及治疗程度分为唇腭裂组(a)?单纯唇裂组(b)?腭裂组(c)和唇腭裂修复后组(d),各组的贫血率分别为43.6%?40.5%?19.7%和17.0%,其中a?b组贫血率均高于d组,但c组与d组贫血率无统计学差别?进行性别和城乡构成比标化后,除d组外,其它各组贫血率均高于该组段平均年龄对应的中国居民贫血率?未完全修复的唇腭裂患者的贫血率与性别和城乡差别之间无明显依存关系?在所有患者中,贫血81例,属小细胞低色素贫血的患者有44例,占54.3%?12例跟踪调查的唇腭裂患者,完全修复后hgb有显著性提高,rbc平均值修复前后均在正常范围内?结论:唇腭裂患者贫血的可能性增加,且贫血的主要类型为小细胞低色素贫血?应该对唇腭裂患者,尤其是较小年龄患者的家庭进行科学喂养的广泛宣传,并让他们注重含铁物质的摄入?     

Kinsenoside: A Promising Bioactive Compound from Anoectochilus Species

Kinsenoside is a main active component isolated from plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects, including hepatoprotective, anti-hyperglycemic, anti-hyperliposis, anti-inflammatory, vascular protective and anti-osteoporosis effects and so on, which is contributing to its promising potency in disease treatments. This review aims to recapitulate the pharmacological functions of kinsenoside, as well as its source, extraction, identification, quantitative analysis, pharmacokinetics, synthesis and patent information. The data reported in this work can confirm the therapeutic potential of kinsenoside and provide useful information for further new drug development.     

GuttaFlow充填系统根管封闭性能初探

目的评价GuttaFlow常温流动牙胶充填系统的根管封闭性能。方法30颗单根管牙沿釉牙骨质界截冠,采用冠向下法,使用ProTaper机用镍钛系统预备根管。随机分为3组,每组10颗,分别以GuttaFlow充填系统、冷侧压充填法、连续波热塑牙胶充填术充填根管。采用葡萄糖定量法测定第2、7、14、21、28天从冠方向根方渗漏的葡萄糖量。结果从实验第21天起,GuttaFlow充填系统的葡萄糖渗漏量要明显低于冷侧压充填法(P<0.05),而与连续波热塑牙胶充填术相比没有统计学差异(P>0.05)。结论GuttaFlow充填系统在观测期内具有较好的根管封闭性能。