全文获取类型
收费全文 | 3974篇 |
免费 | 225篇 |
国内免费 | 28篇 |
专业分类
耳鼻咽喉 | 143篇 |
儿科学 | 100篇 |
妇产科学 | 41篇 |
基础医学 | 510篇 |
口腔科学 | 94篇 |
临床医学 | 242篇 |
内科学 | 993篇 |
皮肤病学 | 62篇 |
神经病学 | 453篇 |
特种医学 | 83篇 |
外科学 | 618篇 |
综合类 | 15篇 |
预防医学 | 118篇 |
眼科学 | 66篇 |
药学 | 339篇 |
中国医学 | 8篇 |
肿瘤学 | 342篇 |
出版年
2022年 | 50篇 |
2021年 | 98篇 |
2020年 | 47篇 |
2019年 | 68篇 |
2018年 | 76篇 |
2017年 | 63篇 |
2016年 | 58篇 |
2015年 | 74篇 |
2014年 | 86篇 |
2013年 | 117篇 |
2012年 | 197篇 |
2011年 | 209篇 |
2010年 | 106篇 |
2009年 | 103篇 |
2008年 | 181篇 |
2007年 | 180篇 |
2006年 | 178篇 |
2005年 | 173篇 |
2004年 | 168篇 |
2003年 | 179篇 |
2002年 | 143篇 |
2001年 | 142篇 |
2000年 | 165篇 |
1999年 | 146篇 |
1998年 | 51篇 |
1997年 | 37篇 |
1996年 | 42篇 |
1995年 | 28篇 |
1994年 | 28篇 |
1993年 | 31篇 |
1992年 | 103篇 |
1991年 | 72篇 |
1990年 | 85篇 |
1989年 | 105篇 |
1988年 | 84篇 |
1987年 | 71篇 |
1986年 | 65篇 |
1985年 | 60篇 |
1984年 | 42篇 |
1983年 | 28篇 |
1982年 | 18篇 |
1981年 | 15篇 |
1980年 | 19篇 |
1979年 | 36篇 |
1978年 | 20篇 |
1977年 | 26篇 |
1975年 | 15篇 |
1974年 | 15篇 |
1968年 | 14篇 |
1966年 | 14篇 |
排序方式: 共有4227条查询结果,搜索用时 15 毫秒
1.
IgG-maleimide peroxidase, Fab'-maleimide peroxidase, polymer and monomer types of Fab'-periodate peroxidase were prepared from an antibody against rat lipoamide dehydrogenase, a component of the pyruvate dehydrogenase complex which is located in mitochondria. They were examined for immunohistochemical staining of the rat kidney. Fab'-maleimide peroxidase was the best for staining mitochondrial protein. IgG-maleimide peroxidase and the monomer type of Fab'-periodate peroxidase had the same intensity of staining. The polymer type of Fab'-periodate peroxidase could not stain the lipoamide dehydrogenase. 相似文献
2.
3.
4.
M Noguchi T Taniya K Ueno M Yagi R Izumi K Konishi I Miyazaki 《The Japanese journal of surgery》1990,20(4):448-452
We report herein a rare case of a 26 year old woman with pheochromocytoma complicated by paralytic ileus. She presented with remarkable abdominal distension and respiratory difficulty but was effectively treated by surgical removal of the tumor with preoperative and operative management using alpha and beta adrenergic blocking agents. An excessive and persistent catecholamine production from large tumors or massive metastases characterizes this rare complication, and a review of the English and Japanese literature is given following this report. 相似文献
5.
Yukako Sato Masahiko Aoyama Tomoko Soeda Akihiko Hoshi Mari Honma Teiji Yamamoto 《Clinical neurology》2004,44(8):527-530
A 65-year-old woman with diabetes mellitus and chronic otitis media developed headache, fever, and hoarseness, all of which did not responded to the oral antibiotics. As stiff neck and lower cranial nerve palsies appeared, bacterial meningitis was suspected. Neurological examination revealed the right hearing disturbance, right recurrent laryngeal nerve palsy, left sternocleidomastoid muscle atrophy and bilateral tongue atrophy. The CSF examination revealed mild pleocytosis and elevated protein, but no bacterial organism was cultured from the CSF. CT scans showed bilateral mastoiditis, and the right mastoid process and a posterior part of the petrous bone were eroded, indicating the exposed bony structures to the posterior fossa. MRI scans demonstrated the thickening of the dura mater of the posterior fossa and the right cerebellar tentorium. This is a rare example of bacterial pachymeningitis of the posterior fossa, the clinical symptoms and MRI findings of which resolved solely by antimicrobial agents without corticosteroid. 相似文献
6.
Yoshiko Ogata Yoshihiro Mori Hikari Koga Kazuya Awai Yukako Arakawa Norihiko Nakanishi Mikio Kataoka Fumikazu Kohi 《Nihon Kokyūki Gakkai zasshi》2004,42(9):837-841
A 22-year-old man was urgently admitted for pneumothorax. He continued complaining of exertional dyspnea and dry cough after the pneumothorax healed. About three months later, an atypical pulmonary mycobacteriosis by mycobacterium kansasii was identified. Exertional dyspnea increased after chemotherapy was administered, and the patient was readmitted because of difficulty in daily life activities. Chest radiographs and CT scans showed bilateral pulmonary hyperinflation and a narrowed heart shadow. There was also marked combined ventilatory impairment, as identified by a respiratory function test. Furthermore, the histological findings of surgically removed lung tissue revealed accumulation of lymphocytes in the wall of a small bronchus. Idiopathic bronchiolitis obliterans was diagnosed from the clinical course and clinical findings. The patient is now being monitored and is awaiting lung transplantation. 相似文献
7.
8.
K Imura A Okada Y Fukui H Kawahara M Yagi A Kubota S Kanaya S Kamata Y Nagata 《JPEN. Journal of parenteral and enteral nutrition》1988,12(5):496-504
In 97 neonates receiving total parenteral nutrition in the postoperative period, clinical assessment was made for a newly devised amino acid solution (PF-I-III) from the standpoint of plasma amino acid profile and nutritional effect. These amino acid solutions prepared are characterized by the high concentration of branched-chain amino acids up to 40%, increased arginine and decreased glycine, phenylalanine and methionine as compared with commercially available solutions. In the PF group, each amino acid was kept within the range of standard value. Correlation between plasma amino acid profiles and the dose of each amino acid administered was obtained, from which minimum, standard, and maximum doses for each amino acid was determined. Based on these values, we proposed new formula for neonates which elicits no abnormal plasma amino acid pattern even when amino acids are administered at the dosage level of 1.5-2.5 g/kg/day. 相似文献
9.
S Kanba E Suzuki S Nomura T Nakaki G Yagi M Asai E Richelson 《Journal of psychiatry & neuroscience : JPN》1994,19(4):265-269
We determined the inhibition-dissociation constant (Ki) of a number of neuroleptics for D1 receptors of normal human brain tissue using [3H]SCH23390 [R-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1H-3[benzazepine-7- ol]. SCH23390 had the highest affinity with a Ki of 0.76 nM. Among clinically used drugs, propericiazine showed the highest affinity with a Ki of 10 nM. When neuroleptics were classified according to chemical structures, the Ki values were as follows. Phenothiazines ranged from 10 nM to 250 nM. Butyrophenones ranged from 45 nM to 250 nM. Thioxanthenes ranged from 12 nM to 340 nM. Orthopramines were more than 10,000 nM. The Ki values for the binding site of this study were significantly correlated with those reported in studies using animal brain. The possible relationship between D1 receptors and negative symptoms is discussed. 相似文献
10.