全文获取类型
收费全文 | 8299篇 |
免费 | 543篇 |
国内免费 | 36篇 |
专业分类
耳鼻咽喉 | 36篇 |
儿科学 | 173篇 |
妇产科学 | 113篇 |
基础医学 | 1170篇 |
口腔科学 | 77篇 |
临床医学 | 852篇 |
内科学 | 1675篇 |
皮肤病学 | 322篇 |
神经病学 | 1195篇 |
特种医学 | 475篇 |
外科学 | 1217篇 |
综合类 | 70篇 |
一般理论 | 1篇 |
预防医学 | 377篇 |
眼科学 | 130篇 |
药学 | 498篇 |
中国医学 | 11篇 |
肿瘤学 | 486篇 |
出版年
2022年 | 48篇 |
2021年 | 97篇 |
2020年 | 68篇 |
2019年 | 91篇 |
2018年 | 110篇 |
2017年 | 105篇 |
2016年 | 123篇 |
2015年 | 166篇 |
2014年 | 185篇 |
2013年 | 265篇 |
2012年 | 393篇 |
2011年 | 369篇 |
2010年 | 238篇 |
2009年 | 268篇 |
2008年 | 461篇 |
2007年 | 482篇 |
2006年 | 462篇 |
2005年 | 453篇 |
2004年 | 411篇 |
2003年 | 455篇 |
2002年 | 408篇 |
2001年 | 265篇 |
2000年 | 228篇 |
1999年 | 199篇 |
1998年 | 96篇 |
1997年 | 82篇 |
1996年 | 79篇 |
1995年 | 93篇 |
1994年 | 54篇 |
1993年 | 72篇 |
1992年 | 115篇 |
1991年 | 128篇 |
1990年 | 123篇 |
1989年 | 120篇 |
1988年 | 105篇 |
1987年 | 106篇 |
1986年 | 107篇 |
1985年 | 129篇 |
1984年 | 84篇 |
1983年 | 80篇 |
1982年 | 60篇 |
1981年 | 45篇 |
1979年 | 89篇 |
1978年 | 56篇 |
1977年 | 59篇 |
1976年 | 52篇 |
1974年 | 61篇 |
1973年 | 52篇 |
1972年 | 42篇 |
1970年 | 42篇 |
排序方式: 共有8878条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
6.
Neil H Pliskin Alia N Ammar Joseph W Fink S Kristian Hill Aaron C Malina Alona Ramati Kathleen M Kelley Raphael C Lee 《Journal of the International Neuropsychological Society》2006,12(1):17-23
The clinical presentation of electrical injury commonly involves physical, cognitive, and emotional complaints. Neuropsychological studies, including case reports, have indicated that electrical injury (EI) survivors may experience a broad range of impaired neuropsychological functions, although this has not been clarified through controlled investigation. In this study, we describe the neuropsychological test findings in a series of 29 EI patients carefully screened and matched to a group of 29 demographically similar healthy electricians. Participants were matched by their estimated premorbid intellectual ability. Multivariate analysis of variance was used to assess group differences in the following neuropsychological domains: attention and mental speed, working memory, verbal memory, visual memory, and motor skills. EI patients performed significantly worse on composite measures of attention/mental speed and motor skills, which could not be explained by demographic differences, injury parameters, litigation status, or mood disturbance. Results suggest that cognitive changes do occur in patients suffering from electrical injury. 相似文献
7.
A. Nakao H. Toyokawa A. Tsung M. A. Nalesnik D. B. Stolz J. Kohmoto A. Ikeda K. Tomiyama T. Harada T. Takahashi R. Yang M. P. Fink K. Morita A. M. K. Choi N. Murase 《American journal of transplantation》2006,6(10):2243-2255
Carbon monoxide (CO), a byproduct of heme catalysis, was shown to have potent cytoprotective and anti-inflammatory effects. In vivo recipient CO inhalation at low concentrations prevented ischemia/reperfusion (I/R) injury associated with small intestinal transplantation (SITx). This study examined whether ex vivo delivery of CO in University of Wisconsin (UW) solution could ameliorate intestinal I/R injury. Orthotopic syngenic SITx was performed in Lewis rats after 6 h cold preservation in control UW or UW that was bubbled with CO gas (0.1-5%) (CO-UW). Recipient survival with intestinal grafts preserved in 5%, but not 0.1%, CO-UW improved to 86.7% (13/15) from 53% (9/17) with control UW. At 3 h after SITx, grafts stored in 5% CO-UW showed improved intestinal barrier function, less mucosal denudation and reduced inflammatory mediator upregulation compared to those in control UW. Preservation in CO-UW associated with reduced vascular resistance (end preservation), increased graft cyclic guanosine monophosphate levels (1 h), and improved graft blood flow (1 h). Protective effects of CO-UW were reversed by ODQ, an inhibitor of soluble guanylyl cyclase. In vitro culture experiment also showed better preservation of vascular endothelial cells with CO-UW. The study suggests that ex vivo CO delivery into UW solution would be a simple and innovative therapeutic strategy to prevent transplant-induced I/R injury. 相似文献
8.
The vagal nerve as a link between the nervous and immune system in the instance of polymicrobial sepsis 总被引:5,自引:0,他引:5
Wolfram Kessler Tobias Traeger Alexandra Westerholt Friederike Neher Marlene Mikulcak Antje Müller Stefan Maier Claus-Dieter Heidecke 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》2006,391(2):83-87
Background The role of the vagal nerve in the autonomic nervous system is widely well known. Recently, an additional function was revealed
serving as a connector between the nervous and immune system. This connection is called the “cholinergic inflammatory pathway.”
Through stimulation of the acetylcholine receptors located upon the macrophages, the “unspecific” immune system can be directly
influenced.
Methods The vagal nerve was completely transected directly posterior to its passage through the diaphragm. The effect of complete
vagotomy was analyzed using a murine model of polymicrobial peritonitis (colon ascendens stent peritonitis, CASP). Survival
and clinical course of vagotomized or sham-operated mice were analyzed in the CASP model.
Results After CASP surgery, vagotomy led to a significantly increased mortality (64.7%) in comparison to sham-vagotomized animals
(34%). No difference in the bacterial load of various tissues (lung, liver, spleen, blood, lavage fluid, and kidney) from
septic animals with or without vagotomy was observed. Vagotomized animals reveal elevated serum cytokine levels (TNF, IL-6,
IL-10, and MCP-1) 20 h after the induction of polymicrobial peritonitis.
Conclusion The vagal nerve is therefore an important modulator of the immune system.
W. Kessler and T. Traeger contributed equally to this work
Best of Forum Papers presented at the Annual Meeting of the German Society of Surgery, 2–5 May 2006, Berlin, Germany 相似文献
9.
T. Schneider W. Menke B. Fink W. Rüther K. P. Schulitz 《Archives of orthopaedic and trauma surgery》1997,116(1-2):46-49
In this study 17 patients with recurrent dislocation of the patella were followed up 10 years after their Goldthwait operation. The subjective and clinical findings were excellent or good in 70%. X-radiographs indicated osteoarthritis of the femoropatellar joint in 60%. Concerning the aetiopathological factors, we found an increased external torsion of the afflicted extremity (measured by computed tomography). 相似文献
10.