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排序方式: 共有372条查询结果,搜索用时 31 毫秒
1.
2.
Brandon JC; Teplick SK; Haskin PH; Sammon JK; Muhr WF; Hofmann AF; Gambescia RA; Zitomer N 《Radiology》1988,166(3):665-667
The authors describe their experience with methyl tertiary butyl ether (MTBE) in a larger series of patients than previously reported in order to acquaint physicians with both its effectiveness for dissolution of common bile duct calculi and the limitations of its use. Ten patients with 13 biliary calculi underwent percutaneous stone dissolution treatment with the experimental cholesterol solvent, MTBE. Three stones completely dissolved within 30 minutes, seven were reduced in size, and three were visibly unaffected. All stones not completely dissolved were easily extracted by means of a stone basket except for one in a patient taken to surgery. Although MTBE perfusion is an effective technique for management of biliary calculi, practitioners should be aware that its use is quite time consuming and its odor difficult to control. 相似文献
3.
M. E. J. van Velthoven M. D. de Smet R. O. Schlingemann M. Magnani F. D. Verbraak 《Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie》2006,244(9):1119-1123
Background Evaluating the presence of leakage on fluorescein angiography (FA) in patients with age-related macular degeneration (AMD) retreated with photodynamic therapy (PDT) can be difficult. New diagnostic tools such as optical coherence tomography (OCT) might help to optimize PDT management.Methods Thirty AMD patients scheduled for regular follow-up FA in conjunction with PDT treatment were also scanned with OCT. Follow-up data at 9 months were retrieved from the patients’ medical records. Inter-observer agreement [kappa (κ) coefficient] for the presence of leakage on FA, for OCT parameters for leakage, and agreement between FA and OCT evaluations were calculated. The indication for retreatment was evaluated using the leakage analysis based on FA alone, OCT alone, and both examinations combined, and compared to the actual follow-up of the patients at 9 months.Results Agreement between the two observers for the presence of leakage on FA was moderate (κ=0.51). OCT agreement between the two observers for the presence of leakage was good (κ=0.85). Agreement between FA and OCT for the presence of leakage was poor (κ=0.16). Follow-up data at 9 months on all patients were analyzed. Seven out of 30 patients were not retreated at the time of examination, and four of these patients (57%) remained stable without further treatment. Twenty-three patients did receive a PDT treatment at the time of examination; and eight of these patients did not show leakage on OCT, and five of these patients (62%) remained stable without additional treatment. In contrast, only three out of 15 patients (20%) with leakage on both FA and OCT remained stable during this 9 month follow-up period.Conclusions Inter-observer agreement for the presence of leakage was moderate for FA and good for OCT. There was considerable disagreement between leakage as judged by OCT and by FA. OCT could be of help in the decision regarding PDT retreatment. Assuming that 57% of the patients without leakage either on FA or OCT would remain stable without retreatment, the rate of probable ineffective retreatment could be reduced from 35% to 20%.There was no financial support for this study. The authors have full access to the data and will allow Graefe’s Archive for Clinical and Experimental Ophthalmology to review the data if requeste.d 相似文献
4.
Darai E; Leblanc M; Walker-Combrouze F; Bringuier AF; Madelenat P; Scoazec JY 《Human reproduction (Oxford, England)》1998,13(5):1346-1352
We evaluated the immunohistochemical expression of cadherins and CD44
variants in 20 endometriomas, 20 cystadenomas, 20 borderline ovarian
tumours as well as 20 ovarian carcinomas, and the serological and cystic
fluid concentrations of soluble E-cadherin and soluble CD44 standard
(sCD44sdt) in 20 endometriomas, 20 cystadenomas, six borderline and 11
carcinomas of the ovary. In endometriomas, immunostaining of E- and
N-cadherin was negative (20 and 30% respectively). CD44 H, v3 and v6
immunostaining were detected in 63, 10 and 40% respectively. A difference
in immunostaining for E-cadherin was found between endometriomas and
cystadenomas (P < 0.001) and for N- cadherin between endometriomas and
carcinomas (P < 0.001). A difference in CD44H immunostaining was
observed between endometriomas and cystadenomas (P < 0.035) but not with
borderline ovarian tumours and carcinomas. No difference in serum
concentrations of soluble E- cadherins and CD44 standard was found between
the four groups of tumours. Cystic fluid concentrations of E-cadherin were
lower in endometriomas than in borderline tumours and ovarian carcinomas (P
< 0.001). High concentrations of soluble CD44 standard cystic fluid were
found in endometriomas than in other ovarian cysts. Endometriomas and
borderline tumours share alterations of cadherins and CD44 isoforms which
may help in the understanding of the aggressive and invasive potentials of
endometriotic cells.
相似文献
5.
Genital asymmetry in men 总被引:1,自引:0,他引:1
This study examined genital asymmetry in a large sample of men. The
probands were 6544 non-delinquent men who were interviewed by the Kinsey
Institute for Research in Sex, Gender and Reproduction from 1938 to 1963.
The measures were four indicators of penile and scrotal asymmetry, along
with self-reported handedness, from Kinsey's interview protocol. Most men
reported some degree of lateral asymmetry in their flaccid penis and in
their testicles; less asymmetry was reported for their erect penis. The
asymmetry typically occurred in the left direction, and this pattern
occurred in both right- and nonright- handers. However, this 'leftward'
pattern was significantly less pronounced in nonright-handers. The results
are discussed in relation to previous findings of genital asymmetry in men,
the possible relationship of genital asymmetry to functional cerebral
asymmetry, and recent data suggesting genital asymmetry may predict
patterns of cognitive performance and genital/sexual organ cancers.
相似文献
6.
E Legius C E de Die-Smulders F Verbraak H Habex R Decorte P Marynen J P Fryns J J Cassiman 《Journal of medical genetics》1994,31(4):340-341
A three generation family with Rieger eye malformation sequence is described. No other abnormalities were present apart from the eye malformation. Linkage to EGF and D4S193 localised in 4q25 was excluded and this indicates that Rieger eye malformation is genetically different from typical Rieger syndrome with teeth and umbilical anomalies. 相似文献
7.
A. F. M. Verbraak J. E. W. Beneken J. M. Bogaard A. Versprille 《Medical & biological engineering & computing》1995,33(6):776-783
A computer controlled mechanical lung model has been developed for testing lung function equipment, validation of computer
programs and simulation of impaired pulmonary mechanics. The construction, function and some applications are described. The
physical model is constructed from two bellows and a pipe system representing the alveolar lung compartments of both lungs
and airways, respectively. The bellows are surrounded by water simulating pleural and interstitial space. Volume changes of
the bellows are accomplished via the fluid by a piston. The piston is driven by a servo-controlled electrical motor whose
input is generated by a microcomputer. A wide range of breathing patterns can be simulated. The pipe system representing the
trachea connects both bellows to the ambient air and is provided with exchangeable parts with known resistance. A compressible
element (CE) can be inserted into the pipe system. The fluid-filled space around the CE is connected with the water compartment
around the bellows; The CE is made from a stretched Penrose drain. The outlet of the pipe system can be interrupted at the
command of an external microcomputer system. An automatic sequence of measurements can be programmed and is executed without
the interaction of a technician. 相似文献
8.
Immune deficiencies in chronic intestinal pseudo-obstruction 总被引:1,自引:0,他引:1
ML Forchielli MC Young AF Flores D. Richardson CW Lo 《Acta paediatrica (Oslo, Norway : 1992)》1997,86(10):1077-1081
Aim: Chronic intestinal pseudo-obstruction has been associated with urinary disorders, myopathy, and ophthalmoplegia in adults and cholelithiasis in children. We observed a high percentage of total-parenteral-nutrition-dependent patients with pseudo-obstruction and recurrent infections requiring gammaglobulin infusions. Methods: AH records for 23 children with chronic intestinal pseudo-obstruction (10 females and 13 males, mean age 9.8 y ± 4.9 y, range 4–24 y) referred for a nutritional evaluation from 1992 to 1995 were reviewed. Chronic intestinal pseudo-obstruction was diagnosed by clinical, radiographic findings and antroduodenal manometry. Intestinal full-thickness biopsies were performed in seven children. Results: Hypogammaglobulinemia was diagnosed in 18 patients (78%): 16 patients had various immunoglobulin deficiencies and 2 had selective antibody deficiency. Intravenous gammaglobulin was administered in 14 patients. Other medical conditions affecting the children are summarized as follows: autonomic dysfunction in 10 patients (43%), recurrent hypoglycemia in 9 (39%), asthma in 9 (39%), cholecystitis in 7 (30%), low serum carnitine level in 6 (26%), urinary dysfunction in 6 (26%), pancreatitis in 5 (22%), behavioral problems in 5 (22%), myopathy in 2 (9%), idiopathic thrombocytopenia in 2 (8%), velopharyngeal insufficiency in 1 (4%), oculocutaneous albinism in 1 (4%), Pierre-Robin syndrome in 1 (4%), and protein C deficiency in 1 (4%). Munchausen syndrome was suspected in two patients. Conclusions: Chronic intestinal pseudo-obstruction appears to be associated with immune deficiencies. It is unclear if the immune deficiencies, intestinal pseudo-obstruction, and the other medical conditions have a common underlying etiology. Repeated infections may be due to impaired immune function in children with chronic intestinal pseudo-obstruction. We recommend screening for immune deficiencies in children with chronic intestinal pseudo-obstruction. 相似文献
9.
Complications from improperly placed biliary stents are not uncommon. Free loose wires from the ends of an uncovered stent can irritate and damage adjacent mucosal surfaces. Effective management can be achieved via percutaneous placement of a second stent to alter the orientation of the original stent. 相似文献
10.
AF Jorm H Christensen AS Henderson PA Jacomb AE Korten A Mackinnon 《Age and ageing》1996,25(2):126-129
Formal assessment of cognitive decline with cognitive tests can be difficult, requiring either two measurement points or a comparison of 'hold' with 'don't hold' tests. Informant-based assessment provides an alternative approach because informants can adopt a longitudinal perspective and directly rate cognitive change. A study was carried out to assess the validity of informant ratings collected by means of the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE). A community sample of 500 subjects aged 74 or over underwent four cognitive tests on two occasions 3½ years apart. On the second occasion, informants filled out the IQCODE. Subjects rated as having moderate or severe decline were found to have greater change on the cognitive tests. These findings support the validity of informant ratings of cognitive decline. 相似文献