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排序方式: 共有273条查询结果,搜索用时 31 毫秒
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LN Weinberger MJ Zirwas JC English III 《Journal of the European Academy of Dermatology and Venereology》2007,21(2):156-162
Male genital oedema can be defined as swelling or the appearance of swelling of the scrotum and/or the penile shaft and prepuce. Despite the various causes of genital oedema reported in the published work, a concise approach to the evaluation and management has not been sufficiently addressed. 相似文献
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Nguyen Tuyen Trat Tiffany Tieu Ngoc Thanh Vu Linda Sokal-Gutierrez Karen 《Maternal and child health journal》2022,26(9):1811-1819
Maternal and Child Health Journal - Vietnam’s post-war globalization, economic development, and urbanization have contributed to a nutrition transition from traditional diets to... 相似文献
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Yang PY Almofti MR Lu L Kang H Zhang J Li TJ Rui YC Sun LN Chen WS 《第二军医大学学报》2006,27(6):637-637
Polygonum multiflorum stilbeneglycoside (PMS) is a water-soluble fraction of Polygonum multiflorum Thunb. , one of the most famous tonic traditional Chinese medicines, that has protective effects on the cardiovascular system. The purpose of the present study is to elucidate the effects of PMS on macrophage-derived foam cell functions and the reduction of severity of atherosclerosis in hypercholesterolemic New Zealand White (NZW) rabbits. NZW rabbits were fed for 12 weeks with a normal diet, a high cholesterol diet, or a high cholesterol diet associated with irrigation with different doses of PMS (25, 50, or 100 mg/kg). Treatment of NZW rabbits fed with high cholesterol diet with 100 mg/kg PMS attenuated the increase in plasma cholesterol, low-density lipoprotein cholesterol, very low-density lipoprotein cholesterol, and plasma triglyceride. Treatment with 50 and 100 mg/kg PMS caused 43% and 60% decrease in atherosclerotic lesioned area ratio to total surface area, respectively. In U937 foam cells, PMS could decrease the high expression of intercellular adhesion molecule (ICAM)-1 protein and the vascular endothelial growth factor (VEGF) protein levels in the medium induced by oxidized lipoprotein when analyzed by flow cytometry. The results proved that PMS is a powerful agent against atherosclerosis and that PMS action could possibly be through the inhibition of the expression of ICAM-1 and VEGF in foam cells. 相似文献
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Joshua G. Cohen Tuyen Kiet Jacob Y. Shin Alexander E. Sherman Chad A. Hamilton Rebecca A. Brooks Stefanie M. Ueda Lee-May Chen Daniel S. Kapp John K. Chan 《Gynecologic oncology》2013,128(1):128-131
ObjectiveTo determine the rate and factors associated with publication of plenary abstract presentations from the Society of Gynecologic Oncologists annual meeting.MethodsPlenary presentations were reviewed from 2000 to 2005. A PubMed search was performed to identify subsequent peer-reviewed publication of these presentations. Chi-squared test and logistic regression were used for statistical analyses.ResultsOf 378 main, focused or express plenary presentations, 173 (45.8%) involved multiple and 205 (54.2%) single institutions. The types of study include: chart review (29.4%), cohort study (28.0%), translational (23.5%), and randomized clinical trial (6.9%). 309 (81.7%) of presentations were subsequently published. The median time from presentation to publication was 14 months (range: 1–85). Studies from multiple vs. single institutions were more likely to be published (87.9% vs. 76.6%; p = 0.005). In addition, randomized controlled trials were more likely to be published compared with chart review, cohort, and translation research (92.3% vs. 83.8%, 77.4%, and 74.2%; p < 0.01). On multivariate analysis, multi-institutional studies (OR = 2.28, 95% CI = 1.28–4.04; p = 0.005) and type of study (OR = 1.64, 95% CI = 1.19–2.26; p = 0.002) were independent factors associated with publication. In addition, multi-institutional studies had longer times from presentation to publication compared with their counterparts.ConclusionsA high percentage of plenary presentations at the Society of Gynecologic Oncologists annual meeting resulted in subsequent publication. Multi-institutional studies and randomized clinical trials were more likely to be published. 相似文献
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Faqir Muhammad Tuyen Duong Thanh Nguyen Ahmad Raza Bushra Akhtar 《Drug and chemical toxicology》2017,40(4):489-497
Nanotechnology has gained significant penetration to different fields of medicine including drug delivery, disease interrogation, targeting and bio-imaging. In recent years, efforts have been put forth to assess the use of this technology in biodetoxification. In this review, we will discuss the current status of nanostructured biomaterials/nanoparticle (NP)-based technologies as a candidate biodetoxifying agent. Patient hospitalization due to illicit drug consumption, suicidal attempts and accidental toxin exposure are major challenges in the medical field. Overdoses of drugs/toxic chemicals or exposure to bacterial toxins or poisons are conventionally treated by voiding the stomach, administering activated charcoal or by using specific antidotes, if the toxin is known. Because of the limitations of these methods for safe and effective detoxification, advancements in nanotechnology may offer novel ways in intoxication support by using nanostructured biomaterials, such as liposomes, micellar nanocarriers, liquid crystalline nanoassemblies and ligand-based NPs. 相似文献
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Nguyen Van Vinh Chau Nguyen Thi Thu Hong Nghiem My Ngoc Tran Tan Thanh Phan Nguyen Quoc Khanh Lam Anh Nguyet Le Nguyen Truc Nhu Nguyen Thi Han Ny Dinh Nguyen Huy Man Vu Thi Ty Hang Nguyen Thanh Phong Nguyen Thi Hong Que Pham Thi Tuyen Tran Nguyen Hoang Tu Tran Tinh Hien Ngo Ngoc Quang Minh Le Manh Hung Nguyen Thanh Truong Lam Minh Yen H. Rogier van Doorn Nguyen Thanh Dung Guy Thwaites Nguyen Tri Dung Le Van Tan for the OUCRU COVID- research group 《Emerging infectious diseases》2021,27(1):310
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Anaya HD Hoang T Golden JF Goetz MB Gifford A Bowman C Osborn T Owens DK Sanders GD Asch SM 《Journal of general internal medicine》2008,23(6):800-807
Background HIV testing is cost-effective in unselected general medical populations, yet testing rates among those at risk remain low,
even among those with regular primary care. HIV rapid testing is effective in many healthcare settings, but scant research
has been done within primary care settings or within the US Department of Veteran’s Affairs Healthcare System.
Objectives We evaluated three methods proven effective in other diseases/settings: nurse standing orders for testing, streamlined counseling,
and HIV rapid testing.
Design Randomized, controlled trial with three intervention models: model A (traditional counseling/testing); model B (nurse-initiated
screening, traditional counseling/testing); model C (nurse-initiated screening, streamlined counseling/rapid testing).
Participants Two hundred fifty-one patients with primary/urgent care appointments in two VA clinics in the same city (one large urban hospital,
one freestanding outpatient clinic in a high HIV prevalence area).
Measurements Rates of HIV testing and receipt of results; sexual risk reduction; HIV knowledge improvement.
Results Testing rates were 40.2% (model A), 84.5% (model B), and 89.3% (model C; p = <.01). Test result receipt rates were 14.6% (model
A), 31.0% (model B), 79.8% (model C; all p = <.01). Sexual risk reduction and knowledge improvement did not differ significantly between counseling methods.
Conclusions Streamlined counseling with rapid testing significantly increased testing and receipt rates over current practice without
changes in risk behavior or posttest knowledge. Increased testing and receipt of results could lead to earlier disease identification,
increased treatment, and reduced morbidity/mortality. Policymakers should consider streamlined counseling/rapid testing when
implementing routine HIV testing into primary/urgent care. 相似文献
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Manganese G8 dendrimers targeted to oxidation‐specific epitopes: In vivo MR imaging of atherosclerosis
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