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Uterine myomata and outcome of assisted reproduction 总被引:5,自引:8,他引:5
Ramzy AM; Sattar M; Amin Y; Mansour RT; Serour GI; Aboulghar MA 《Human reproduction (Oxford, England)》1998,13(1):198-202
The aim of this work was to study the effect of uterine myomata on the
implantation rate and outcome in in-vitro fertilization (IVF) and
intracytoplasmic sperm injection (ICSI). Among 406 patients, 51 (12.6%)
were found to have uterine corporeal myomata. Twelve patients were excluded
from the study as they had large myomata, submucous myomata or intramural
myomata encroaching on the cavity. These patients were advised to have
myomectomy before being enrolled in the IVF/ICSI programme. The remaining
patients (n = 39) were sorted according to the number, site and size of the
myomata as assessed by transvaginal sonography. Three patients had more
than one myoma. Most of the myomata were subserous (72.7%) and the mean
diameter of the myomata was 3.5 +/- 0.9 cm. A control group (n = 367) was
chosen with normal uteri and no history of uterine reconstruction surgery.
The mean age of myoma patients was 34.7 +/- 3.6 years as compared to 34.0
+/- 4.4 years in the control group. The age, period of infertility, body
mass index, duration and number of human menopausal gonadotrophin ampoules
needed for stimulation, oestradiol levels, number of oocytes retrieved and
the fertilization rate were not significantly different in the myoma
patients compared to the control group. Fifteen myoma patients (38.5%)
subsequently showed one or more pregnancy sacs on ultrasonography of which
three (20%) spontaneously aborted during the first trimester and two
(13.3%) had preterm labour, as compared to 123 (33.5%), 19 (15.5%) and nine
(7.3%) respectively, among the control group (P = 0.27, 0.33 and 0.21). In
conclusion, uterine corporeal myomata, not encroaching on the cavity and
<7 cm in mean diameter, do not affect the implantation or miscarriage
rates in IVF or ICSI.
相似文献
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四氯偶氮苯(3,3’,4,4’tetrachloroazobenzene,TCAB)和四氯氧化偶氮苯(3,3’,4,4’tetrachloroazoxybenzene,TCAOB)是在合成氯代或二氯代苯胺类除草剂时生成的污染废弃物。此类除草剂经... 相似文献
6.
G Saggese S Bertelloni GI Baroncelli G Federico 《Acta paediatrica (Oslo, Norway : 1992)》1992,81(6-7):532-535
Osteoporosis is a common finding in Turner's syndrome. To test the hypothesis that calcitonin deficiency may contribute to bone mineral loss in Turner's syndrome, we studied basal and calcium-stimulated (2 mg/kg body weight in 5 min) levels of total calcitonin, extractable calcitonin and katacalcin in 15 girls with Turner's syndrome and osteoporosis. Fifteen age-matched healthy girls were studied as controls. Both basal calcitonin (total and extractable) and katacalcin values were not significantly different in patients with Turner's syndrome in comparison with those of the controls. The calcium stimulation test showed a similar "C" cell secretory reserve in both groups. The calculation of delta CT/delta iCa of total and extractable calcitonin and delta KC/delta iCa, which accounts for individual variations in serum ionized calcium increases, did not show any significant difference between girls with Turner's syndrome and controls. We conclude that calcitonin deficiency is not a causative factor of osteoporosis in girls with Turner's syndrome and that in this syndrome long-life estrogen deficiency does not impair "C" cell secretory activity. 相似文献
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中国九省居民膳食、体力活动与血压水平关系的纵向分析研究 总被引:1,自引:0,他引:1
目的 通过构建多水平模型,对中国九省居民饮食、体力活动与血压水平之间的关系进行纵向分析.方法 以"中国健康与营养调查"追踪调查项目中参加1997、2000、2004和2006年四轮调查中至少一次调查的18岁及以上成年人(男性6706名,女性7140名)为研究对象,分性别拟合包括个体和调查时间两个水平的发展模型,分析膳食中盐、蔬菜、水果、脂肪和蛋白质摄入量以及中重度体力活动时间对SBP和DBP的影响.结果 在调整年龄、教育程度、BMI、饮酒和能量摄入量等因素之后,四轮调查女性个体平均盐摄入量与SBP呈正相关(β=0.0481,s-x=0.0178,P<0.01);男女性个体平均蔬菜摄入量与SBP呈负相关(P<0.01),其回归系数估计值分别为-0.0063、-0.0068,即个体四次调查日均蔬菜摄入量每增加100 g,其SBP会降低0.6mm Hg(1 mm Hg=0.133kPa)以上,另外,男女性个体平均蔬菜摄入量同DBP亦呈负相关(P<0.01).对同一调查时间的不同个体或不同调查时间的同一个体来说,男女性水果摄入量和SBP呈负相关,其回归系数估计值分别为-0.0029、-0.0031.中重度体力活动时间与男女性SBP和女性DBP均呈负相关(P<0.05).不过,膳食总脂肪和蛋白质摄入量与血压水平之间并无关联.结论 膳食中盐、蔬菜和水果摄入量以及中重度体力活动时间与血压水平有关.限盐、增加蔬菜和水果摄入量、提高各项体力活动水平、积极控制体重等生活方式的转变是控制血压水平的重要方法. 相似文献
8.
GI van Boxel M Hart A Kiszely S Appleton 《Annals of the Royal College of Surgeons of England》2013,95(8):561-564
Introduction
Elective laparoscopic cholecystectomy (LC) is performed routinely as day-case surgery. Most hospital trusts have a policy of no routine postoperative outpatient follow-up although there are no formal guidelines on this. The aim of this retrospective study was to identify the incidence of complications, the degree of symptom resolution and patient satisfaction with a view to formally appraising the need for outpatient follow-up.Methods
Patients who underwent LC in the period between February 2011 and June 2012 were contacted retrospectively by telephone. A standardised questionnaire was used to ascertain the incidence of surgical site infection (SSI), other complications, symptom resolution and patient satisfaction.Results
A total of 211 responses were collected. The rate of SSI was 7.6% (n=16), with the only specific risk factor being smoking (p=0.027). All other complications had a combined incidence of 7% (n=15). There was complete resolution of symptoms in 64% of patients. Of the 36% of patients with residual symptoms, 45% described abdominal discomfort or pain, 41% described reflux symptoms and 14% complained of diarrhoea. Patient satisfaction was very high (96%), yet 33% of patients visited their general practitioner postoperatively in relation to their surgery.Conclusions
Patients are highly satisfied with elective day-case LC. However, SSI is not uncommon, occurring in 1 in 13 patients. Although the majority of patients experience complete symptom resolution, a significant proportion do not. In our experience, routine outpatient follow-up is not required. Nevertheless, the lack of formal follow-up may prove a missed learning opportunity, potentially resulting in inappropriate patient selection for surgery. 相似文献9.
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Zhilenkov A. V. Khakina E. A. Troshin P. A. Karimov I. F. Deryabin D. G. 《Pharmaceutical Chemistry Journal》2019,53(4):312-317
Pharmaceutical Chemistry Journal - Three water-soluble C60-fullerene derivatives functionalized by anionic adducts of various chemical compositions and structures were prepared in highly specific... 相似文献