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排序方式: 共有435条查询结果,搜索用时 11 毫秒
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Meng-Lay Lin Hetal Patel Judit Remenyi Christopher R.S. Banerji Chun-Fui Lai Manikandan Periyasamy Ylenia Lombardo Claudia Busonero Silvia Ottaviani Alun Passey Philip R. Quinlan Colin A. Purdie Lee B. Jordan Alastair M. Thompson Richard S. Finn Oscar M. Rueda Carlos Caldas Jesus Gil R. Charles Coombes Frances V. Fuller-Pace Andrew E. Teschendorff Laki Buluwela Simak Ali 《Oncotarget》2015,6(25):21685-21703
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Chorea is a neurological adverse effect of oral contraceptive pills (OCPs). The onset of chorea following OCPs usage varies widely from few weeks to several years. We report a rare case of chorea which developed within a week of starting OCPs in an adolescent girl with polycystic ovarian disease.KEY WORDS: Chorea, oral contraceptive pills, polycystic ovarian disease 相似文献
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Ankit Batra Jayachandran Perumal Kalaiyarasi Krishnarathinam Kannan Nikita Mehra Prasanth Ganesan Parathan Karunakaran Manikandan Dhanushkodi Gangothri Selvarajan Arun Kumar Rajan Sivasree Kesana Trivadi Ganesan Tenali G. Sagar Venkatraman Radhakrishnan 《Indian journal of hematology & blood transfusion》2021,37(3):463
There has been a surge in haploidentical hematopoietic stem cell transplantation (HSCT) in India recently. However, there is a paucity of data on haploidentical HSCT from India. The report is an analysis of data of haploidentical HSCT performed at our center. Analysis of patients with acute leukemia or chronic myeloid leukemia who underwent haploidentical HSCT during 2014–2019 was performed. The graft versus host disease (GVHD) prophylaxis was post-transplant Cyclophosphamide with Mycophenolate-mofetil and Cyclosporine. All patients were transfused peripheral blood stem cells from donors. Overall survival (OS) was calculated using the Kaplan–Meier method. Twenty-one patients underwent haploidentical HSCT. Fourteen-patients were males. The median age of patients was 15 years. Fludarabine with total body irradiation was the most common conditioning regimen (n = 15, 71.4%). The median duration for neutrophil and platelet engraftment was 14 days. Cumulative incidence of acute and chronic GVHD was 19%, and 38% respectively. The median follow-up was 26 months and the two-year OS was 38%. Twelve (57%) patients died during the study period, 8 patients (38%) died from transplant-related mortality (TRM), and 4 from disease relapse. Sepsis was the cause of death in six of the eight TRM. Nine out of 21 patients (42.8%) are leukemia-free on follow-up. Haploidentical HSCT is a promising modality of treatment in patients who have no suitable matched donors. Though the TRM remains high, good disease control was achieved in 42.8% of patients. Multi-drug resistant bacterial infection remains a challenge in performing haploidentical HSCT in developing countries. 相似文献
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Mehra Nikita Christopher Vasanth Dhanushkodi Manikandan Radhakrishnan Venkatraman Ganesan Trivadi S Ganesharajah Selvaluxmy Sagar Tenali Gnana Ganesan Prasanth 《International journal of clinical pharmacy》2020,42(2):662-666
International Journal of Clinical Pharmacy - Background There is limited data on specific antiemetic protocols for control of chemotherapy-induced nausea/vomiting (CINV) caused by weekly cisplatin... 相似文献
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Sampath Marimuthu Abdul Abdul Rahuman Arivarasan Vishnu Kirthi Thirunavukkarasu Santhoshkumar Chidambaram Jayaseelan Govindasamy Rajakumar 《Parasitology research》2013,112(12):4105-4112
The developments of resistance and persistence to chemical insecticides and concerns about the non-target effects have prompted the development of eco-friendly mosquito control agents. The aim of this study was to investigate the larvicidal activities of synthesized cobalt nanoparticles (Co NPs) using bio control agent, Bacillus thuringiensis against malaria vector, Anopheles subpictus and dengue vector, Aedes aegypti (Diptera: Culicidae). The synthesized Co NPs were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR), Field-emission scanning electron microscopy (FESEM) with energy dispersive X-ray spectroscopy, and Transmission electron microscopy (TEM). XRD analysis showed three distinct diffraction peaks at 27.03°, 31.00°, and 45.58° indexed to the planes 102, 122, and 024, respectively on the face-centered cubic cobalt acetate with an average size of 85.3 nm. FTIR spectra implicated role of the peak at 3,436 cm?1 for O–H hydroxyl group, 2924 cm?1 for methylene C–H stretch in the formation of Co NPs. FESEM analysis showed the topological and morphological appearance of NPs which were found to be spherical and oval in shape. TEM analysis showed polydispersed and clustered NPs with an average size of 84.81 nm. The maximum larvicidal mortality was observed in the cobalt acetate solution, B. thuringiensis formulation, and synthesized Co NPs against fourth instar larvae of A. subpictus and A. aegypti with LC50 values of 29.16, 8.12, 3.59 mg/L; 34.61, 6.94, and 2.87 mg/L; r 2 values of 0.986, 0.933, 0.942; 0.962, 0.957, and 0.922, respectively. 相似文献
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Thirunavukkarasu Arun Babu Shanthi Ananthakrishnan P. Jayakumar Poonam Kullu 《Indian journal of pediatrics》2014,81(5):504-506
Colitis is a rare manifestation of enteric fever in children. Toxic megacolon complicating typhoid colitis is even rarer and requires early recognition and aggressive management due to the high mortality associated with this condition. The authors report a rare case of Toxic megacolon secondary to typhoid colitis in a seven-year-old girl. 相似文献