全文获取类型
收费全文 | 541篇 |
免费 | 19篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 14篇 |
儿科学 | 3篇 |
妇产科学 | 12篇 |
基础医学 | 27篇 |
口腔科学 | 1篇 |
临床医学 | 20篇 |
内科学 | 186篇 |
皮肤病学 | 1篇 |
神经病学 | 4篇 |
特种医学 | 5篇 |
外科学 | 57篇 |
综合类 | 6篇 |
一般理论 | 1篇 |
预防医学 | 10篇 |
眼科学 | 4篇 |
药学 | 9篇 |
中国医学 | 7篇 |
肿瘤学 | 194篇 |
出版年
2024年 | 2篇 |
2023年 | 7篇 |
2022年 | 11篇 |
2021年 | 47篇 |
2020年 | 6篇 |
2019年 | 28篇 |
2018年 | 61篇 |
2017年 | 59篇 |
2016年 | 12篇 |
2015年 | 8篇 |
2014年 | 48篇 |
2013年 | 37篇 |
2012年 | 46篇 |
2011年 | 38篇 |
2010年 | 39篇 |
2009年 | 35篇 |
2008年 | 10篇 |
2007年 | 8篇 |
2006年 | 6篇 |
2005年 | 9篇 |
2004年 | 9篇 |
2003年 | 4篇 |
2002年 | 1篇 |
2001年 | 3篇 |
2000年 | 2篇 |
1998年 | 2篇 |
1997年 | 1篇 |
1996年 | 1篇 |
1995年 | 1篇 |
1993年 | 3篇 |
1992年 | 1篇 |
1991年 | 4篇 |
1990年 | 3篇 |
1989年 | 5篇 |
1988年 | 2篇 |
1983年 | 1篇 |
1980年 | 1篇 |
排序方式: 共有561条查询结果,搜索用时 0 毫秒
1.
2.
3.
4.
Jana Hudcova Syed Talha Qasmi Robin Ruthazer Ahsan Waqas Syed Basit Haider Roman Schumann 《Transplantation proceedings》2021,53(1):119-123
PurposeWe examined the role of obesity and intraoperative red blood cell (RBC) and platelet transfusion in early allograft dysfunction (EAD) following liver transplantation (LT).MethodsThis is a retrospective analysis of 239 adult deceased-donor LT recipients over a 10-year period. EAD was defined by Olthoff’s criteria. Data collection included donor (D) and recipient (R) age, body mass index (BMI) ≥ 35 kg/m2, diabetes mellitus, allograft macrosteatosis, and intraoperative (RBC) and platelet administration. We employed logistic regression to evaluate associations of these factors with EAD. Results are presented as odds ratios (OR) and 95% confidence intervals (CI) with corresponding P values. A P ≤ .05 was considered statistically significant.ResultsEAD occurred in 85 recipients (36%). Macrosteatosis data were available for 199 donors. In the multivariate analyses, BMI-D ≥ 35 kg/m2 increased the odds of developing EAD by 156% in the entire cohort (OR 2.56, 95% CI 1.09-6.01) and by 187% in recipients with macrosteatosis data (n = 199, OR 2.87, 95% CI 1.15-7.15). Each unit of RBCs increased the odds for EAD by 8% (OR 1.08, 95% CI 1.02-1.14) and, for the subgroup of 238 recipients with macrosteatosis data, by 9% (OR 1.09, 95% CI 1.02-1.16).ConclusionWe found a significant independent association of donor obesity and intraoperative RBC transfusion with EAD but no such association for platelet administration, MELD score, age, recipient obesity, and diabetes. 相似文献
5.
Ali A. Rabaan Abdul Hawil Abas Trina Ekawati Tallei Mona A. Al-Zaher Noor M. Al-Sheef Fatimawali Esraa Z. Al-Nass Eba A. Al-Ebrahim Yunus Effendi Rinaldi Idroes Mather F. Alhabib Hussain A. Al-Fheid Ahmad Akroman Adam Talha Bin Emran 《Journal of medical virology》2023,95(1):e28306
Monkeypox is a rare zoonotic disease caused by infection with the monkeypox virus. The disease can result in flu-like symptoms, fever, and a persistent rash. The disease is currently spreading throughout the world and prevention and treatment efforts are being intensified. Although there is no treatment that has been specifically approved for monkeypox virus infection, infected patients may benefit from using certain antiviral medications that are typically prescribed for the treatment of smallpox. The drugs are tecovirimat, brincidofovir, and cidofovir, all of which are currently in short supply due to the spread of the monkeypox virus. Resistance is also a concern, as widespread replication of the monkeypox virus can lead to mutations that produce monkeypox viruses that are resistant to the currently available treatments. This article discusses monkeypox disease, potential drug targets, and management strategies to overcome monkeypox disease. With the discovery of new drugs, it is hoped that the problem of insufficient drugs will be resolved, and it is not anticipated that drug resistance will become a major issue in the near future. 相似文献
6.
Sema Aydodu Ipek Akil Talha Akil Caner Kabasakal Refik Killi Sevgi Mir Rait Yaci 《Pediatrics international》2004,46(1):67-71
BACKGROUND: The aim of the present study was to investigate renal vascular resistive changes in children with different stages of liver cirrhosis without obvious renal failure. METHODS: Twenty-nine children (14 girls, 15 boys, mean age 11.6 years) with cirrhosis and 20 healthy children (mean age 10.3 years) were investigated for renal vascular resistance with Doppler ultrasonography, urinary sodium, N-acetyl-beta-D glucosaminidase (NAG) and microalbuminuria excretion. RESULTS: The measurements of renal resistive indexes (RRI) were significantly higher in cirrhotic patients than the control group (0.69 +/- 0.07 vs 0.62 +/- 0.02, P < 0.0001). RRI measurement was found to be increased in decompensated cirrhotic patients than in compensated cirrhotic patients (0.73 +/- 0.05 vs 0.67 +/- 0.08, P < 0.0001). A significant positive relationship was observed between RRI and child score (r = 0.53). Urine NAG/Cr ratio was significantly higher in cirrhotic patients than in the control subjects (P < 0.001). Microalbumin concentrations were increased in the patients with decompensated cirrhosis than in the controls (P = 0.02). Patients with ascites and portal hypertension showed increased RRI values. CONCLUSIONS: We conclude that patients with cirrhosis are at risk of renal deterioration, which can not be detected by serum urea, creatinine, and glomerular filtration rate. The increase of RRI is associated with the progress of hepatocellular disease, and also the development of ascites and portal hypertension. Elevated urinary sodium excretion, elevated urinary NAG/Cr ratio and microalbuminuria might have a prognostic value especially in patients with Child scores> 6. Hence, monitoring RRI is a non-invasive means of studying early renal hemodynamic alteration in childhood cirrhosis. 相似文献
7.
8.
9.
10.