全文获取类型
收费全文 | 5065篇 |
免费 | 244篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 123篇 |
妇产科学 | 144篇 |
基础医学 | 1217篇 |
口腔科学 | 59篇 |
临床医学 | 493篇 |
内科学 | 904篇 |
皮肤病学 | 50篇 |
神经病学 | 324篇 |
特种医学 | 130篇 |
外科学 | 335篇 |
综合类 | 14篇 |
一般理论 | 2篇 |
预防医学 | 452篇 |
眼科学 | 62篇 |
药学 | 623篇 |
2篇 | |
中国医学 | 18篇 |
肿瘤学 | 343篇 |
出版年
2023年 | 29篇 |
2022年 | 72篇 |
2021年 | 139篇 |
2020年 | 89篇 |
2019年 | 113篇 |
2018年 | 128篇 |
2017年 | 96篇 |
2016年 | 103篇 |
2015年 | 119篇 |
2014年 | 167篇 |
2013年 | 200篇 |
2012年 | 317篇 |
2011年 | 322篇 |
2010年 | 162篇 |
2009年 | 135篇 |
2008年 | 286篇 |
2007年 | 311篇 |
2006年 | 257篇 |
2005年 | 233篇 |
2004年 | 193篇 |
2003年 | 180篇 |
2002年 | 174篇 |
2001年 | 71篇 |
2000年 | 52篇 |
1999年 | 67篇 |
1998年 | 34篇 |
1996年 | 42篇 |
1992年 | 45篇 |
1991年 | 73篇 |
1990年 | 80篇 |
1989年 | 55篇 |
1988年 | 57篇 |
1987年 | 68篇 |
1986年 | 70篇 |
1985年 | 71篇 |
1984年 | 47篇 |
1983年 | 34篇 |
1982年 | 23篇 |
1979年 | 37篇 |
1978年 | 33篇 |
1976年 | 34篇 |
1975年 | 44篇 |
1974年 | 38篇 |
1973年 | 53篇 |
1972年 | 34篇 |
1971年 | 36篇 |
1970年 | 34篇 |
1969年 | 36篇 |
1968年 | 26篇 |
1967年 | 31篇 |
排序方式: 共有5315条查询结果,搜索用时 15 毫秒
1.
2.
Erika Cecon Anna Ivanova Marine Luka Florence Gbahou Anne Friederich Jean‐Luc Guillaume Patrick Keller Klaus Knoch Raise Ahmad Philippe Delagrange Michele Solimena Ralf Jockers 《Journal of pineal research》2019,66(2)
Melatonin receptors play important roles in the regulation of circadian and seasonal rhythms, sleep, retinal functions, the immune system, depression, and type 2 diabetes development. Melatonin receptors are approved drug targets for insomnia, non‐24‐hour sleep‐wake disorders, and major depressive disorders. In mammals, two melatonin receptors (MTRs) exist, MT1 and MT2, belonging to the G protein‐coupled receptor (GPCR) superfamily. Similar to most other GPCRs, reliable antibodies recognizing melatonin receptors proved to be difficult to obtain. Here, we describe the development of the first monoclonal antibodies (mABs) for mouse MT1 and MT2. Purified antibodies were extensively characterized for specific reactivity with mouse, rat, and human MT1 and MT2 by Western blot, immunoprecipitation, immunofluorescence, and proximity ligation assay. Several mABs were specific for either mouse MT1 or MT2. None of the mABs cross‐reacted with rat MTRs, and some were able to react with human MTRs. The specificity of the selected mABs was validated by immunofluorescence microscopy in three established locations (retina, suprachiasmatic nuclei, pituitary gland) for MTR expression in mice using MTR‐KO mice as control. MT2 expression was not detected in mouse insulinoma MIN6 cells or pancreatic beta‐cells. Collectively, we report the first monoclonal antibodies recognizing recombinant and native mouse melatonin receptors that will be valuable tools for future studies. 相似文献
3.
Peffault de Latour Rgis Huynh Lynn Ivanova Jasmina I. Totev Todor Bilginsoy Mehmet Antin Joseph Roy Anuja Duh Mei Sheng 《Annals of hematology》2020,99(4):743-752
Annals of Hematology - This study assessed treatment patterns and healthcare resource utilization (HRU) of patients with severe aplastic anemia (SAA) with insufficient response to immunosuppressive... 相似文献
4.
Jeroen M. van de Pol Jurjen G. Geljon Svetlana V. Belitser Geert W.J. Frederix Anke M. Hövels Marcel L. Bouvy 《Research in social & administrative pharmacy》2019,15(1):70-76
Introduction
The nature of community pharmacy is changing, shifting from the preparation and distribution of medicines to the provision of cognitive pharmaceutical services (CPS); however, often the provision of traditional services leaves little time for innovative services. This study investigated the time community pharmacists spend on the tasks and activities of daily practice and to what extent they are able to implement CPS-related services in daily practice.Methods
Self-reporting work sampling was used to register the activities of community pharmacists. A smartphone application, designed specifically for this purpose, alerted participants to register their current activity five times per working day for 6 weeks. Participants also completed an online survey about baseline characteristics.Results
Ninety-one Dutch community pharmacists provided work-sampling data (7848 registered activities). Overall, 51.5% of their time was spent on professional activities, 35.4% on semi-professional activities, and 13.1% on non-professional activities. The proportion of time devoted to CPS decreased during the workweek, whereas the time spent on traditional task increased.Discussion and conclusion
This study shows it is feasible to collect work-sampling data using smartphone technology. Community pharmacists spent almost half of their time on semi-professional and non-professional activities, activities that could be delegated to other staff members. In practice, the transition to CPS is hampered by competing traditional tasks, which prevents community pharmacists from profiling themselves as pharmaceutical experts in daily practice. 相似文献5.
6.
7.
8.
9.
10.