全文获取类型
收费全文 | 683篇 |
免费 | 38篇 |
国内免费 | 6篇 |
专业分类
耳鼻咽喉 | 2篇 |
儿科学 | 46篇 |
妇产科学 | 65篇 |
基础医学 | 50篇 |
口腔科学 | 8篇 |
临床医学 | 55篇 |
内科学 | 104篇 |
皮肤病学 | 13篇 |
神经病学 | 10篇 |
特种医学 | 78篇 |
外科学 | 43篇 |
综合类 | 21篇 |
预防医学 | 65篇 |
眼科学 | 15篇 |
药学 | 16篇 |
中国医学 | 1篇 |
肿瘤学 | 135篇 |
出版年
2023年 | 6篇 |
2022年 | 9篇 |
2021年 | 8篇 |
2020年 | 13篇 |
2019年 | 10篇 |
2018年 | 10篇 |
2017年 | 9篇 |
2016年 | 13篇 |
2015年 | 9篇 |
2014年 | 26篇 |
2013年 | 33篇 |
2012年 | 32篇 |
2011年 | 32篇 |
2010年 | 29篇 |
2009年 | 33篇 |
2008年 | 34篇 |
2007年 | 22篇 |
2006年 | 15篇 |
2005年 | 23篇 |
2004年 | 11篇 |
2003年 | 21篇 |
2002年 | 16篇 |
2001年 | 14篇 |
2000年 | 13篇 |
1999年 | 13篇 |
1998年 | 19篇 |
1997年 | 12篇 |
1996年 | 18篇 |
1995年 | 12篇 |
1994年 | 18篇 |
1993年 | 18篇 |
1992年 | 21篇 |
1991年 | 19篇 |
1990年 | 14篇 |
1989年 | 15篇 |
1988年 | 16篇 |
1987年 | 18篇 |
1986年 | 10篇 |
1985年 | 14篇 |
1982年 | 5篇 |
1981年 | 5篇 |
1980年 | 4篇 |
1977年 | 3篇 |
1972年 | 2篇 |
1968年 | 3篇 |
1967年 | 2篇 |
1942年 | 2篇 |
1937年 | 3篇 |
1923年 | 4篇 |
1917年 | 2篇 |
排序方式: 共有727条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
青蒿琥酯皮肤擦剂在小鼠和兔体内的药代动力学研究 总被引:1,自引:0,他引:1
将青蒿琥酯溶于苯二甲酸二甲酯,加适量氨酮制成皮肤擦剂。给兔脱毛后,皮肤涂抹此擦剂25mg/kg后,血药浓度达峰时间平均为2 h,峰浓度平均为1.80μg/ml。药物在兔体内平均驻留时间为3.54 h,清除半衰期约为2.46 h。给小鼠脱毛皮肤涂抹擦剂6.7,31.3和71.4 mg/kg,血药浓度在给药后0.5~4 h达高峰,峰浓度分别为0.82,2.05和7.11μg/ml,体内药物平均驻留时间为3.39,2.79及3.54 h,清除半衰期为2.35,1.93及2.45 h。可见,给兔及小鼠皮肤擦剂后,青蒿琥酯吸收良好,血药浓度维持时间较长。 相似文献
5.
6.
7.
8.
Dale W Stovall Andrea S Fernandez Stephen A Cohen 《JSLS, Journal of the Society of Laparoendoscopic Surgeons》2006,10(1):11-15
OBJECTIVES: To assess laparoscopic training curriculums in US Obstetrics and Gynecology residency programs. METHODS: A list of E-mail addresses was obtained for the accredited Obstetrics and Gynecology residency programs in the US from the CREOG Directory of Obstetric-Gynecologic Residency Programs and Directors. An E-mail survey containing 8 questions regarding laparoscopy training was sent to all residency directors with current E-mail addresses. RESULTS: Seventy-four residency directors responded to the survey for a response rate of 41%. Residency programs from all sections of the US were included in the study. Results of the survey indicate that 69% of residency programs had implemented a formal laparoscopy training program. At least half of the program directors surveyed stated that lack of faculty time and funds were the main barriers to laparoscopic surgery training. Seventy-two percent of those surveyed thought that in the future the health-care industry would demand proof of competency in laparoscopy as standard of care. CONCLUSIONS: Most US Obstetrics and Gynecology residency programs have implemented a formal laparoscopy training curriculum, use more than one method to train their residents, and involve almost half of their faculty on average in training residents to perform laparoscopic surgery. 相似文献
9.
10.
Long-term neurologic and neurosensory sequelae in adult survivors of a childhood brain tumor: childhood cancer survivor study. 总被引:4,自引:0,他引:4
Roger J Packer James G Gurney Judy A Punyko Sarah S Donaldson Peter D Inskip Marilyn Stovall Yutaka Yasui Ann C Mertens Charles A Sklar H Stacy Nicholson Lonnie K Zeltzer Joseph P Neglia Leslie L Robison 《Journal of clinical oncology》2003,21(17):3255-3261
PURPOSE: To describe the neurologic and neurosensory deficits in children with brain tumors (BTs), compare incidence of these deficits with that of a sibling control group, and evaluate the factors associated with the development of these deficits. PATIENTS AND METHODS: Detailed questionnaires were completed on 1,607 patients diagnosed between 1970 and 1986 with a primary CNS tumor. Neurosensory and neurologic dysfunctions were assessed and results compared with those of a sibling control group. Medical records on all patients were abstracted, including radiotherapy dose and volume. RESULTS: Seventeen percent of patients developed neurosensory impairment. Relative to the sibling comparison group, patients surviving BTs were at elevated risk for hearing impairments (relative risk [RR], 17.3; P = <.0001), legal blindness in one or both eyes (RR, 14.8; P = <.0001), cataracts (RR, 11.9; P = <.0001), and double vision (RR, 8.8; P = <.0001). Radiation exposure greater than 50 Gy to the posterior fossa was associated with a higher likelihood of developing any hearing impairment. Coordination and motor control problems were reported in 49% and 26%, respectively, of survivors. Children receiving at least 50 Gy to the frontal brain regions had a moderately elevated risk for motor problems (RR, 2.0; P <.05). Seizure disorders were reported in 25% of patients, including 6.5% who had a late first occurrence. Radiation dose of 30 Gy or more to any cortical segment of the brain was associated with a two-fold elevated risk for a late seizure disorder. CONCLUSION: Children surviving BTs are at significant risk for both early and late neurologic or neurosensory sequelae. These sequelae need to be prospectively monitored. 相似文献