二甲亚砜对人表皮的核酸和蛋白质合成的影响

用体外培养的人的伪表皮作为模型，进行药物毒理学作用的研究，观察了二甲亚砜（ＤＭＳＯ）在不同浓度和不同接触时间条件下，对人的伪表皮细胞脱氧核糖核酸（ＤＮＡ）、核糖核酸（ＲＮＡ）和蛋白质合成的影响：随着接触时间的延长，ＤＮＡ、ＲＮＡ和蛋白质合成均受抑制。低浓度条件下（１％），ＤＮＡ、ＲＮＡ和蛋白质合成增加；在１５～５０％浓度下，ＤＮＡ和蛋白质合成抑制，而ＲＮＡ合成仍增加；在高浓度条件下（７０％～１００％），ＤＮＡ、ＲＮＡ和蛋白质合成均明显抑制。     

Effectiveness of the treatment of chronic non-healing stomach ulcers using copper vapor laser

A group of patients with chronic gastric ulcers received a course of laser treatment with the use of laser on copper vapours. Gastric ulcer was exposed to radiation once in the course of 5 days, the single dose being equal to 10-15 J. Complete healing of the ulcerous defect was attained in 100 out of 110 patients examined. The results of laser therapy were found to be influenced by certain clinical characteristics, namely by age, ulcer size, duration of the last disease exacerbation, and acid-secreting function of the stomach.     

Nephroblastoma with intestinal differentiation

Available are two cases of Wilms's tumor with focal intestinal differentiation. Goblet- and endocrine-like cells as well as those similar to enterocytes were identified in one of the tumors upon electron microscopy. Squamous epithelial, cartilaginous cells, rabdomyoblasts presented in both cases. Problems of histogenesis and prognosis are under discussion.     

Aspects of the morphogenesis of cancer of the endometrium

The paper covers a number of morphogenetic problems of endometrial cancer with reference to multidirectional differentiation of the uterine epithelium affected by tumor. Metaplastic changes of the endometrium observable in three basic variants (tubal, endocervical, squamous cell) can entail dysplasia with resultant malignant transformation. Endometrial cancer shows complex structure of the tumor with sings of multidirectional epithelial differentiation: endometrial, tubal, endocervical, squamous). Morphological features of the tumor and adjacent mucosa, assessed comparatively, suggest a close relationship between the direction of endometrial epithelium differentiation and the new growth histological structure.     

Involvement of fingernails in scabies in an infant

An infant of 10 months, suffering from scabies, has developed multiple involvements of the nail plates on the hands and feet, with detachment of some of them. A diagnostic error has promoted the dissemination of the process. The patient has been etiologically cured by a 10% water/soap suspension of benzyl-benzoate.     

Angiomyolipoma of the kidneys

59 angiomyolipomas were studied: immunohistochemistry (IHC) was used in 24 cases, electron microscopy (EM) in 6 cases. 57 tumors had a typical structure, 2 did not contain fat component. Premelanosomes were found by EM in one tumor. Smooth muscle actin was found in all tumor cells. Involvement of lymph nodes was observed in 2 patients. Histogenesis of this tumor is discussed.