全文获取类型
收费全文 | 29142篇 |
免费 | 1929篇 |
国内免费 | 342篇 |
专业分类
耳鼻咽喉 | 578篇 |
儿科学 | 449篇 |
妇产科学 | 473篇 |
基础医学 | 4843篇 |
口腔科学 | 563篇 |
临床医学 | 2333篇 |
内科学 | 5782篇 |
皮肤病学 | 878篇 |
神经病学 | 2227篇 |
特种医学 | 1784篇 |
外科学 | 4094篇 |
综合类 | 152篇 |
现状与发展 | 3篇 |
一般理论 | 13篇 |
预防医学 | 1205篇 |
眼科学 | 721篇 |
药学 | 2427篇 |
中国医学 | 321篇 |
肿瘤学 | 2567篇 |
出版年
2024年 | 23篇 |
2023年 | 177篇 |
2022年 | 681篇 |
2021年 | 1224篇 |
2020年 | 504篇 |
2019年 | 830篇 |
2018年 | 935篇 |
2017年 | 737篇 |
2016年 | 1094篇 |
2015年 | 1484篇 |
2014年 | 1694篇 |
2013年 | 1813篇 |
2012年 | 2745篇 |
2011年 | 2522篇 |
2010年 | 1454篇 |
2009年 | 1218篇 |
2008年 | 1699篇 |
2007年 | 1631篇 |
2006年 | 1458篇 |
2005年 | 1214篇 |
2004年 | 1063篇 |
2003年 | 891篇 |
2002年 | 760篇 |
2001年 | 634篇 |
2000年 | 544篇 |
1999年 | 406篇 |
1998年 | 180篇 |
1997年 | 135篇 |
1996年 | 97篇 |
1995年 | 106篇 |
1994年 | 82篇 |
1993年 | 79篇 |
1992年 | 148篇 |
1991年 | 133篇 |
1990年 | 120篇 |
1989年 | 122篇 |
1988年 | 83篇 |
1987年 | 94篇 |
1986年 | 74篇 |
1985年 | 69篇 |
1984年 | 42篇 |
1983年 | 38篇 |
1981年 | 26篇 |
1979年 | 41篇 |
1978年 | 23篇 |
1976年 | 28篇 |
1975年 | 22篇 |
1973年 | 23篇 |
1971年 | 24篇 |
1970年 | 22篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
Jae Yun Ahn Jung Bae Park Sungbae Moon Jae Wan Cho Dong Ho Park 《Ophthalmic epidemiology》2020,27(2):105-114
ABSTRACT
Purpose
Work-related eye injuries have been reported with a variety of epidemiologic and clinical characteristics. We aimed to identify epidemiologic characteristics of work-related eye injuries and risk factors associated with severe injury in a large metropolitan city. 相似文献4.
5.
6.
Cheong-Il Shin Sang Joon Park Ji-Hyun Kim Yeonyee Elizabeth Yoon Eun-Ah Park Bon-Kwon Koo Whal Lee 《Korean journal of radiology》2021,22(5):688
ObjectiveTo compare the lumen parameters measured by the location-adaptive threshold method (LATM), in which the inter- and intra-scan attenuation variabilities of coronary computed tomographic angiography (CCTA) were corrected, and the scan-adaptive threshold method (SATM), in which only the inter-scan variability was corrected, with the reference standard measurement by intravascular ultrasonography (IVUS).Materials and MethodsThe Hounsfield unit (HU) values of whole voxels and the centerline in each of the cross-sections of the 22 target coronary artery segments were obtained from 15 patients between March 2009 and June 2010, in addition to the corresponding voxel size. Lumen volume was calculated mathematically as the voxel volume multiplied by the number of voxels with HU within a given range, defined as the lumen for each method, and compared with the IVUS-derived reference standard. Subgroup analysis of the lumen area was performed to investigate the effect of lumen size on the studied methods. Bland-Altman plots were used to evaluate the agreement between the measurements.ResultsLumen volumes measured by SATM was significantly smaller than that measured by IVUS (mean difference, 14.6 mm3; 95% confidence interval [CI], 4.9–24.3 mm3); the lumen volumes measured by LATM and IVUS were not significantly different (mean difference, −0.7 mm3; 95% CI, −9.1–7.7 mm3). The lumen area measured by SATM was significantly smaller than that measured by LATM in the smaller lumen area group (mean of difference, 1.07 mm2; 95% CI, 0.89–1.25 mm2) but not in the larger lumen area group (mean of difference, −0.07 mm2; 95% CI, −0.22–0.08 mm2). In the smaller lumen group, the mean difference was lower in the Bland-Altman plot of IVUS and LATM (0.46 mm2; 95% CI, 0.27–0.65 mm2) than in that of IVUS and SATM (1.53 mm2; 95% CI, 1.27–1.79 mm2).ConclusionSATM underestimated the lumen parameters for computed lumen segmentation in CCTA, and this may be overcome by using LATM. 相似文献
7.
8.
Fabrice Barlesi Edward B. Garon Dong-Wan Kim Enriqueta Felip Ji-Youn Han Joo-Hang Kim Myung-Ju Ahn Mary Jo Fidler Matthew A. Gubens Gilberto de Castro Veerle Surmont Qiao Li Anne C. Deitz Gregory M. Lubiniecki Roy S. Herbst 《Journal of thoracic oncology》2019,14(5):793-801
Introduction
In the phase II/III KEYNOTE-010 study (ClinicalTrials.gov, NCT01905657), pembrolizumab significantly prolonged overall survival over docetaxel in patients with previously treated, programmed death ligand 1–expressing (tumor proportion score ≥ 1%), advanced NSCLC. Health-related quality of life (HRQoL) results are reported here.Methods
Patients were randomized 1:1:1 to pembrolizumab 2 or 10 mg/kg every 3 weeks or docetaxel 75 mg/m2 every 3 weeks. HRQoL was assessed using European Organisation for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire (QLC) Core 30 (C30), EORTC QLQ–Lung Cancer 13 (LC13), and EuroQoL-5D. Key analyses included mean baseline-to-week-12 change in global health status (GHS)/quality of life (QoL) score, functioning and symptom domains, and time to deterioration in a QLQ-LC13 composite endpoint of cough, dyspnea, and chest pain.Results
Patient reported outcomes compliance was high across all three instruments. Pembrolizumab was associated with better QLQ-C30 GHS/QoL scores from baseline to 12 weeks than docetaxel, regardless of pembrolizumab dose or tumor proportion score status (not significant). Compared with docetaxel, fewer pembrolizumab-treated patients had “deteriorated” status and more had “improved” status in GHS/QoL. Nominally significant improvement was reported in many EORTC symptom domains with pembrolizumab, and nominally significant worsening was reported with docetaxel. Significant prolongation in true time to deterioration for the QLQ-LC13 composite endpoint emerged for pembrolizumab 10 mg/kg compared to docetaxel (nominal two-sided p = 0.03), but not for the 2-mg/kg dose.Conclusions
These findings suggest that HRQoL and symptoms are maintained or improved to a greater degree with pembrolizumab than with docetaxel in this NSCLC patient population. 相似文献9.
10.
Clinical usefulness of intraductal ultrasonography for the management of acute biliary pancreatitis
下载免费PDF全文
![点击此处可从《Journal of gastroenterology and hepatology》网站下载免费的PDF全文](/ch/ext_images/free.gif)