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Chlorhexidine susceptibility and Eagle effect in planktonic cells and biofilm of nosocomial isolates
Marchi Ana Paula Farrel Côrtes Marina Vásconez Noguera Saidy Rossi Flavia Levin Anna Sara Figueiredo Costa Silvia Perdigão Neto Lauro Vieira 《European journal of clinical microbiology & infectious diseases》2023,42(6):787-792
European Journal of Clinical Microbiology & Infectious Diseases - The aim of this study is to evaluate the chlorhexidine gluconate (CHG) susceptibility in both planktonic cells and biofilm of... 相似文献
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Saidy Vásconez Noguera Evelyn Patrícia Sánchez Espinoza Marina Farrel Côrtes Izabel Cristina Vilela Oshiro Fernanda de Sousa Spadão Laura Maria Brasileiro Brandão Ana Natiele da Silva Barros Sibeli Costa Bianca Leal de Almeida Paula Gemignani Soriano Alessandra Grassi Salles Mirian Elizabete Marques Escorcio Cristina Madeira Barretti Fernanda Spadotto Baptista Glaura Souza Alvarenga Igor Marinho Leila Suemi Harima Letaif Ho Ye Li Silvia Figueiredo Costa 《American journal of infection control》2021,49(4):512-515
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Ramin Raul Ossami Saidy Irina Sud Franziska Eurich Mustafa Aydin Maximilian Paul Postel Eva Maria Dobrindt Johann Pratschke Dennis Eurich 《Viruses》2021,13(5)
Patients after LT due to combined HBV/HDV infection are considered to be high-risk patients for recurrence of hepatitis B and D. To date, life-long prophylaxis with hepatitis B immunoglobulin (HBIG) and replication control with nucleos(t)ide analogs (NA) remains standard. We examined the course of 36 patients that underwent liver transplantation from 1989 to 2020 for combined HBV/HDV-associated end-stage liver disease in this retrospective study. Seventeen patients eventually discontinued HBIG therapy for various reasons. Their graft function, histopathological findings from routine liver biopsies and overall survival were compared with those that received an unaltered NA-based standard regimen combined with HBIG. The median follow-up was 204 and 227 months, respectively. The recurrence of HBV was 25% and did not differ between the groups of standard reinfection prophylaxis NA/HBIG (21.1%) and HBIG discontinuation (29.4%); (p = 0.56). No significant differences were found regarding the clinical course or histopathological aspects of liver tissue damage (inflammation, fibrosis, steatosis) between these two groups. Overall, and adjusted survival did not differ between the groups. Discontinuation of HBIG in stable patients after LT for combined HBV/HDV did not lead to impaired overall survival or higher recurrence rate of HBV/HDV infection in this long-term follow-up. Therefore, the recommendation of the duration of HBG administration must be questioned. The earliest time of discontinuation remains unclear. 相似文献
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A full-term, female neonate developed acute hypoxemic respiratory failure complicated by persistent pulmonary hypertension
of the newborn (PPHN), and responded to high-frequency oscillatory ventilation (HFOV) and inhaled nitric oxide (iNO). Discontinuation
of iNO was attempted three times and was followed by severe desaturation due to right-to-left shunt through the patent ductus
arteriosus and patent foramen ovale. As a result of iNO dependency state and rebound pulmonary hypertension, the neonate was
maintained on iNO therapy for dipyridamole alone was unsuccessful. However, successful discontinuation of iNO therapy was
achieved by combination of L-Arginine and dipyridamole. Exogeous NO may lead to down regulation of endogenous NO production,
and further lead to rapid hydrolization of cyclic guanosine 3′, 5′ monophosphate (cGMP), the smooth muscle relaxant, by the
enzyme phosphodiesterase. Moreover L-Arginine, the precursor for the formation of endogenous NO, has been found to be deficient
in neonates with PPHN,1,2 so we speculated that by inhibiting phosphodiesterase and administrating L-Arginine smooth muscle relaxation occurred, and
consequent weaning from iNO was achieved. 相似文献
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Posterior mediastinal enteric cysts are infrequently reported. They are mostly asymptomatic 1. The incidence of gastroenteric cysts presenting during immediate neonatal period is rare. Alimentary tract duplications are other rare congenital anomalies and are commonly seen in relation to the ileum. However, the high incidence of associated thoracic or cervical vertebral anomalies with foregut cysts provide an early clue to the diagnosis 2. A detailed timely antenatal scan can increase the awareness regarding such rare condition and help in diagnosis and better outcome. The purpose of this case report is to highlight the clinical diagnosis and management of a neonate with posterior mediastinal gastroenteric cyst. 相似文献
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