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Killmann R. Jaros G. G. Wach P. Graumann R. Moshage W. Renhardt M. Fleischmann R. H. 《Medical & biological engineering & computing》1995,33(5):643-651
A computer simulation study is performed to investigate the method of current density reconstruction to localise myocardial
ischaemia. A computer model of the entire human heart is used to simulate the excitation and repolarisation process in eight
topographically different cases of myocardial ischaemia. The associated magnetocardiogram is calculated at 37 positions of
the KRENIKON* biomagnetic measurement equipment. The method of current density reconstruction is applied at the S-point (the last discemible
deviation from the ST-segment at the end of the QRS-complex) of the MCG to find characteristics of the myocardial ischaemia
simulated by the model. The results show that it is possible to determine the location of the ischaemia. The current density
distribution may be interpreted physiologically in terms of the so-called ‘injury current’. This indicates that magnetocardiography
might be a suitable method for noninvasive ischaemia diagnosis, and further investigations of the current density reconstruction
method for the injury current should be performed on patients with ischaemic heart disease. 相似文献
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