全文获取类型
收费全文 | 3189篇 |
免费 | 171篇 |
国内免费 | 16篇 |
专业分类
耳鼻咽喉 | 16篇 |
儿科学 | 78篇 |
妇产科学 | 26篇 |
基础医学 | 392篇 |
口腔科学 | 51篇 |
临床医学 | 401篇 |
内科学 | 583篇 |
皮肤病学 | 49篇 |
神经病学 | 388篇 |
特种医学 | 230篇 |
外科学 | 514篇 |
综合类 | 11篇 |
预防医学 | 215篇 |
眼科学 | 44篇 |
药学 | 170篇 |
中国医学 | 1篇 |
肿瘤学 | 207篇 |
出版年
2023年 | 18篇 |
2022年 | 40篇 |
2021年 | 80篇 |
2020年 | 51篇 |
2019年 | 55篇 |
2018年 | 67篇 |
2017年 | 55篇 |
2016年 | 57篇 |
2015年 | 73篇 |
2014年 | 93篇 |
2013年 | 140篇 |
2012年 | 185篇 |
2011年 | 194篇 |
2010年 | 112篇 |
2009年 | 103篇 |
2008年 | 157篇 |
2007年 | 164篇 |
2006年 | 161篇 |
2005年 | 168篇 |
2004年 | 179篇 |
2003年 | 119篇 |
2002年 | 113篇 |
2001年 | 91篇 |
2000年 | 107篇 |
1999年 | 60篇 |
1998年 | 34篇 |
1997年 | 23篇 |
1996年 | 28篇 |
1995年 | 23篇 |
1994年 | 21篇 |
1993年 | 19篇 |
1992年 | 44篇 |
1991年 | 53篇 |
1990年 | 45篇 |
1989年 | 36篇 |
1988年 | 33篇 |
1987年 | 30篇 |
1986年 | 27篇 |
1985年 | 17篇 |
1984年 | 28篇 |
1983年 | 19篇 |
1982年 | 12篇 |
1980年 | 14篇 |
1979年 | 18篇 |
1978年 | 15篇 |
1975年 | 14篇 |
1972年 | 16篇 |
1971年 | 12篇 |
1969年 | 13篇 |
1967年 | 20篇 |
排序方式: 共有3376条查询结果,搜索用时 15 毫秒
1.
2.
Ramona A. Cole Anita Bansal Debra M. Moriarity William A. Haber William N. Setzer 《Journal of natural medicines》2007,61(4):414-417
The leaf essential oil of Eugenia zuchowskiae from Monteverde, Costa Rica, has been obtained by hydrodistillation and analyzed by GC–MS. The principal constituents of
E. zuchowskiae leaf oil were α-pinene (28.3%), β-caryophyllene (13.2%), α-humulene (13.1%), and α-copaene (8.1%). The leaf essential oil
of E. zuchowskiae showed pronounced in-vitro cytotoxic activity against MCF-7, MDA-MB-468, and UACC-257 human tumor cell lines. The major components
showed cytotoxic activities comparable to doxorubicin (LC50 14–70 μg/ml). 相似文献
3.
4.
5.
P. K. Lommatzsch I. H. Kirsch 《Documenta ophthalmologica. Advances in ophthalmology》1988,68(3-4):225-238
Therapeutic results are presented with follow-up examinations of at least 5 years (min. 5 years, max. 22 years) after 106Ru/106Rh plaque radiotherapy of posterior uveal melanomas. Out of 227 patients 146 (= 64.3%) could be treated successfully, 37 (= 16.3%) had to be enucleated and are alive, 44 (= 19.4%) died from metastases and 40 (17.6%) from other causes. 75.0% of all small melanomas (T1a) showed an excellent regression pattern to flat scars. Five years after treatment the survival rate was 83.7% (deaths from any causes) respectively 88.2% (deaths from metastases only) and 64.8% (deaths from any causes) respectively 79.7% (deaths from metastases only) ten years after irradiation. 106Ru/106Rh plaque radiotherapy can be recommended for small (Tla, b) and medium sized (T2) choroidal melanomas. 相似文献
6.
High-dose gadoteridol in MR imaging of intracranial neoplasms. 总被引:6,自引:0,他引:6
V M Runge J E Kirsch V J Burke A C Price K L Nelson G S Thomas B L Dean C Lee 《Journal of magnetic resonance imaging : JMRI》1992,2(1):9-18
Twelve patients with a high suspicion of brain metastases by previous clinical or radiologic examinations were studied in a phase III investigation with magnetic resonance (MR) imaging at 1.5 T after a bolus intravenous injection of 0.1 mmol/kg gadoteridol followed at 30 minutes by a second bolus injection of 0.2 mmol/kg gadoteridol. All lesions were best demonstrated (showed greatest enhancement) at the 0.3-mmol/kg (cumulative) dose, with image analysis confirming signal intensity enhancement in the majority of cases after the second gadoteridol injection. More lesions were detected with the 0.3-mmol/kg dose than with the 0.1-mmol/kg dose, and more lesions were detected with the 0.1-mmol/kg dose than on precontrast images. In this limited clinical trial, high-dose gadoteridol injection (0.3-mmol/kg cumulative dose) provided improved lesion detection on MR images specifically in intracranial metastatic disease. 相似文献
7.
8.
S C Robson E Brice C van Rensburg J Kannemeyer R J Hift R E Kirsch 《Suid-Afrikaanse tydskrif vir geneeskunde》1992,82(5):317-320
The therapeutic effects of interferon alpha-2b (Intron A; Scherag) in patients with chronic active hepatitis caused by hepatitis B virus (HBV) were assessed in a randomised, case-controlled clinical trial conducted between January 1988 and June 1990. Treatment involved a short course of prednisone followed by interferon alpha-2b, initially 10 million U by subcutaneous injection, 3 times a week for 16 weeks. All patients were symptomatic, were known to have had hepatitis B surface antigen and hepatitis B e antigen (HBeAg) in their blood for at least 6 months, and had elevated serum aminotransferase activities with histological evidence of chronic active hepatitis. Patients with carcinoma, renal or haematological abnormalities or decompensated cirrhosis were excluded. In 6 of 10 patients randomised to receive interferon and 1 of 10 controls, HBeAg and HBV DNA were cleared from the blood during the 12-month study period (P < 0.05). An indeterminate response with clearance of HBV DNA but persistence of HBeAg was noted in 1 patient receiving interferon. Serum aminotransferase levels decreased only in those patients who had responded to treatment, but this did not reach statistical significance for the group as a whole. Histological studies, where available, showed decreased hepatic periportal necrosis in patients who underwent treatment. Two patients relapsed to HBeAg-positive status 2 months after their initial seroconversion; 1 became clear again during a repeat course of interferon. Side-effects of treatment were common and included fever, malaise, myalgias and myelosuppression. One patient developed hypothyroidism.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
9.
S C Robson C W Spearman M F James P Gordon L Michell K Jaskiewicz P Jacobs M D Voigt R Hickman R E Kirsch 《Suid-Afrikaanse tydskrif vir geneeskunde》1992,82(2):79-82
We present data on 10 patients (5 men and 5 women, aged 21-56 yrs) with end-stage liver disease or tumour who underwent orthotopic liver transplantation at Groote Schuur Hospital between October 1988 and June 1991. Standard surgical techniques were used for procuring the donor liver, the recipient hepatectomy and the implantation of the liver. The venovenous bypass method was used in all but 2 patients. Postoperative immunosuppression was usually achieved with cyclosporin, azathioprine and low-dose steroids. Six patients were treated with prophylactic OKT3. Rejection episodes were treated with bolus doses of intravenous steroids. The indications for liver transplantation included chronic active hepatitis progressing to cirrhosis (5), biliary cirrhosis in association with inflammatory bowel disease (1), sclerosing cholangitis (2), alpha 1-antitrypsin deficiency (1), and tumour (1). All patients with chronic liver disease had experienced at least one complication, examples of which included encephalopathy, bacterial peritonitis, ascites, variceal bleeding and septicaemia. Serious postoperative complications included acute rejection of the transplanted liver, renal and liver failure that responded to intensive care support and medical management. One patient died on the 11th postoperative day with complications of bleeding oesophageal ulcer, shock and fungaemia. The remaining patients are alive and well 1-31 months after transplantation. 相似文献
10.