全文获取类型
收费全文 | 19583篇 |
免费 | 1133篇 |
国内免费 | 71篇 |
专业分类
耳鼻咽喉 | 220篇 |
儿科学 | 635篇 |
妇产科学 | 487篇 |
基础医学 | 2797篇 |
口腔科学 | 945篇 |
临床医学 | 2139篇 |
内科学 | 3869篇 |
皮肤病学 | 437篇 |
神经病学 | 1680篇 |
特种医学 | 391篇 |
外科学 | 1729篇 |
综合类 | 189篇 |
一般理论 | 10篇 |
预防医学 | 2162篇 |
眼科学 | 499篇 |
药学 | 1332篇 |
中国医学 | 89篇 |
肿瘤学 | 1177篇 |
出版年
2023年 | 197篇 |
2022年 | 377篇 |
2021年 | 726篇 |
2020年 | 441篇 |
2019年 | 643篇 |
2018年 | 712篇 |
2017年 | 515篇 |
2016年 | 509篇 |
2015年 | 622篇 |
2014年 | 808篇 |
2013年 | 1007篇 |
2012年 | 1589篇 |
2011年 | 1713篇 |
2010年 | 850篇 |
2009年 | 738篇 |
2008年 | 1285篇 |
2007年 | 1214篇 |
2006年 | 1148篇 |
2005年 | 1051篇 |
2004年 | 898篇 |
2003年 | 823篇 |
2002年 | 786篇 |
2001年 | 166篇 |
2000年 | 140篇 |
1999年 | 132篇 |
1998年 | 160篇 |
1997年 | 99篇 |
1996年 | 94篇 |
1995年 | 69篇 |
1994年 | 70篇 |
1993年 | 68篇 |
1992年 | 75篇 |
1991年 | 86篇 |
1990年 | 73篇 |
1989年 | 55篇 |
1988年 | 65篇 |
1987年 | 59篇 |
1986年 | 62篇 |
1985年 | 39篇 |
1984年 | 50篇 |
1983年 | 43篇 |
1982年 | 43篇 |
1981年 | 44篇 |
1980年 | 38篇 |
1979年 | 47篇 |
1977年 | 26篇 |
1975年 | 24篇 |
1973年 | 32篇 |
1972年 | 38篇 |
1970年 | 31篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
Paula Cristina Galati Paula Garcia Chiarello Belinda Pinto Simões 《Nutrition and cancer》2016,68(1):86-93
Changes in resting energy expenditure (REE) of cancer patients vary depending on type of tumor, treatment time point and kind of treatment. Little is known about REE of acute leukemia adult patients after treatment, especially with results related to body weight or fat free mass (FFM). This study aimed to assess changes in REE of acute leukemia adult patients before and after the first remission induction. Evaluation of REE was performed by indirect calorimetry and predicted REE was calculated by Harris-Benedict equation. Weight and height were measured and compared to a control group of healthy individuals. FFM was assessed by bioelectrical impedance for adjusting REE values. We evaluated 18 patients and 26 healthy individuals. At diagnosis, patients presented REE, REE/weight, and REE/FFM higher than the controls. Reductions of REE, REE/weight, and REE/FFM were also observed in patients after the first cycle of chemotherapy. The predicted REE for the patients group showed significant lower value compared with measured REE. Before the first cycle of chemotherapy REE was increased but undergoes a reduction after treatment, reaching values similar to the controls. For predictive Harris-Benedict equation, stress factors should be added to avoid underestimation of REE before and after chemotherapy. 相似文献
4.
Jerome Marley Julia Taylor Jane Brocksom Kath Schubach Andrea Nixon Paula Allchorne Susanne Vahr Lauridsen 《International Journal of Urological Nursing》2020,14(1):5-12
A series of three World Café events centred on the topic of developing an Educational Framework for Urological Nursing [EFUN] were held by the British Association of Urological Nurses [BAUN], the European Association of Urology Nurses [EAUN] and the Australian and New Zealand Urological Nursing Society [ANZUNS] between 2017 and 2019. About 376 urology nurses participated in these “conversations that matter” and generated 1047 individual response items that were grouped into themes to assist the three associations to take the creation of an EFUN to the next level. Areas explored centred on four aspects: what any agreed educational framework for urology nursing should contain; the academic level at which education should be provided; who should be recruited as collaborators on writing an educational framework and, lastly, just how any emergent framework should be used. Analysis of the conversational data indicate that there exists within the urological nursing community a collective wisdom regarding their educational needs and how these needs should be met. 相似文献
5.
6.
7.
8.
Rubens Souza de OLIVEIRA Lanna Jamile Corrêa da COSTA Fernanda Atanaena Gon?alves de ANDRADE Wilson UIEDA Luzia Fátima Alves MARTORELLI Ana Paula de Arruda Geraldes KATAOKA Elizabeth Salbé Travassos da ROSA Pedro Fernando da Costa VASCONCELOS Armando de Souza PEREIRA Ant?nio Ismael Barros do CARMO Marcus Emanuel Barroncas FERNANDES 《Revista do Instituto de Medicina Tropical de S?o Paulo》2015,57(6):497-503
The outbreaks of rabies in humans transmitted by Desmodus rotundus in 2004 and 2005,
in the northeast of the Brazilian State of Para, eastern Amazon basin, made this a
priority area for studies on this zoonosis. Given this, the present study provides
data on this phenomenon in an urban context, in order to assess the possible
circulation of the classic rabies virus (RABV) among bat species in Capanema, a town
in the Amazon basin. Bats were collected, in 2011, with mist nets during the wet and
dry seasons. Samples of brain tissue and blood were collected for virological and
serological survey, respectively. None of the 153 brain tissue samples analyzed
tested positive for RABV infection, but 50.34% (95% CI: 45.67-55.01%) of the serum
samples analyzed were seropositive. Artibeus planirostris was the most common
species, with a high percentage of seropositive individuals (52.46%, 95% CI: 52.31
52.60%). Statistically, equal proportions of seropositive results were obtained in
the rainy and dry seasons (c2 = 0.057, d.f. = 1, p = 0.88). Significantly
higher proportions of males (55.96%, 95% CI: 48.96-62.96%) and adults (52.37%, 95%
CI: 47.35-57.39%) were seropositive. While none of the brain tissue samples tested
positive for infection, the high proportion of seropositive specimens indicates that
RABV may be widespread in this urban area. 相似文献
9.
Benedita Sampaio-Maia Mónica Moreira-Rodrigues Paula Serr?o Manuel Pestana 《Nephrology, dialysis, transplantation》2006,21(2):314-323
BACKGROUND: A primary tubular sodium handling abnormality has been implicated in the edema formation of nephrotic syndrome. Dopamine synthesized by renal proximal tubules behaves as an endogenous natriuretic hormone by activating D(1)-like receptors as a paracrine/autocrine substance. METHODS: We examined the time courses of the urinary excretion of sodium, protein and dopamine in puromycin aminonucleoside (PAN)-treated and control rats. The rats were sacrificed during greatest sodium retention (day 7) as well as during negative sodium balance (day 14) for the evaluation of renal aromatic l-amino acid decarboxylase (AADC) activity, the enzyme responsible for the synthesis of renal dopamine. Also, the influence of volume expansion (VE) and the effects of the D(1)-like agonist fenoldopam (10 microg/kg bw/min) on natriuresis and on proximal tubular Na(+),K(+)-ATPase activity were examined on day 7. RESULTS: The daily urinary excretion of dopamine was decreased in PAN-treated rats, from day 5 and beyond. This was accompanied by a marked decrease in the renal AADC activity, on days 7 and 14. During VE, the fenoldopam-induced decrease in proximal tubular Na(+),K(+)-ATPase activity was more pronounced in PAN-treated rats than in controls. However, the urinary sodium excretion during fenoldopam infusion was markedly increased in control rats but was not altered in PAN-treated animals. CONCLUSION: PAN nephrosis is associated with a blunted renal dopaminergic system activity which may contribute to enhance the proximal tubular Na(+),K(+)-ATPase activity. However, the lack of renal dopamine appears not to be related with the overall renal sodium retention in a state of proteinuria. 相似文献
10.
Maren T Scheuner William C Whitworth Henraya McGruder Paula W Yoon Muin J Khoury 《Genetics in medicine》2006,8(8):525-531
PURPOSE: We examined the performance of a familial risk assessment method that stratifies risk for early-onset coronary heart disease by considering the number of relatives with coronary disease, degree of relationship, lineage, and age at diagnosis. METHODS: By using data from the HealthStyles 2003 survey, we assessed the associations between familial risk and early-onset coronary heart disease, diabetes, hypercholesterolemia, hypertension, and obesity. By using area under the curve statistics, we evaluated the discriminatory ability of various risk assessment models. RESULTS: Of 4,035 respondents, 60% were female and 72% were white, with a mean age of 48.8 years. After adjustment for demographics, strong and moderate risk were significantly associated with approximately a five- and twofold risk of early-onset coronary disease, respectively. After adjustment for demographics and personal history of cardiovascular disease, strong familial risk was also significantly associated with diabetes, hypercholesterolemia, hypertension, and obesity. A risk assessment model that included familial risk, demographics, and personal history of diabetes, hypercholesterolemia, hypertension, and obesity was most optimal with an area under the curve statistic of 87.2% CONCLUSIONS: Familial risk assessment can stratify risk for early-onset coronary heart disease. Several conditions associated with increased familial risk can be prevented. These results have important implications for risk assessment and risk-reducing interventions. 相似文献