全文获取类型
收费全文 | 710篇 |
免费 | 31篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 42篇 |
妇产科学 | 26篇 |
基础医学 | 72篇 |
口腔科学 | 11篇 |
临床医学 | 49篇 |
内科学 | 132篇 |
皮肤病学 | 6篇 |
神经病学 | 24篇 |
特种医学 | 105篇 |
外科学 | 64篇 |
综合类 | 62篇 |
预防医学 | 33篇 |
眼科学 | 17篇 |
药学 | 36篇 |
肿瘤学 | 61篇 |
出版年
2022年 | 9篇 |
2021年 | 7篇 |
2020年 | 9篇 |
2019年 | 6篇 |
2018年 | 15篇 |
2017年 | 7篇 |
2016年 | 11篇 |
2015年 | 24篇 |
2014年 | 12篇 |
2013年 | 20篇 |
2012年 | 28篇 |
2011年 | 32篇 |
2010年 | 26篇 |
2009年 | 19篇 |
2008年 | 21篇 |
2007年 | 25篇 |
2006年 | 28篇 |
2005年 | 24篇 |
2004年 | 10篇 |
2003年 | 26篇 |
2002年 | 30篇 |
2001年 | 17篇 |
2000年 | 16篇 |
1999年 | 20篇 |
1998年 | 34篇 |
1997年 | 29篇 |
1996年 | 23篇 |
1995年 | 20篇 |
1994年 | 14篇 |
1993年 | 10篇 |
1992年 | 7篇 |
1991年 | 3篇 |
1990年 | 10篇 |
1989年 | 19篇 |
1988年 | 17篇 |
1987年 | 19篇 |
1986年 | 15篇 |
1985年 | 9篇 |
1984年 | 9篇 |
1983年 | 10篇 |
1982年 | 6篇 |
1981年 | 7篇 |
1980年 | 7篇 |
1979年 | 3篇 |
1978年 | 3篇 |
1976年 | 3篇 |
1975年 | 8篇 |
1974年 | 2篇 |
1914年 | 2篇 |
1886年 | 2篇 |
排序方式: 共有745条查询结果,搜索用时 0 毫秒
1.
The purpose of this study is to show the spectrum of adjacent organ invasion and to make a brief review of hepatic alveolar hydatid disease (AHD), using CT and MR imaging. We retrospectively reviewed CT and MR images of three patients with various adjacent organ invasions surgically and histologically proven to be AHD. Local invasion to right kidney and adrenal, right hemidiaphragm and lung were detected in one patient, right adrenal in another patient and gall bladder, duodenum, gastric wall and pancreas invasion in the other. AHD may rarely extend to the gall bladder, stomach, duodenum, pancreas, right adrenal and kidney, diaphragm, pleura and lung. The extension of the disease outside the liver is usually encountered in patients with large, peripherally located masses in the advanced stage of the disease. 相似文献
2.
C McKenzie BAppSc P Megaw BAppSc I Morgan PhD MK Boelen PhD 《Clinical & experimental ophthalmology》1997,25(4):79-81
Deprivation of form vision by the fitting of translucent occluders suppressed the diurnal cycling of enkephalinergic amacrine cells (the ENSLI amacrine cells), in the chicken. Daily periods of normal vision or enforcing temporal contrast using strobe lighting appeared to restore normal functioning of the ENSLI cells. These results suggest that the ENSLI cells are involved in retinal circuits that assess the quality of the visual image and control eye growth. 相似文献
3.
Ovarian cancer is, in most cases, a lethal disease as it is virtually impossible to diagnose at an early stage and almost impossible to treat successfully when detected at an advanced stage. In postmenopausal women, there is no prevention for ovarian cancer but oophorectomy. Therefore, from the gynecological oncological perspective, where benign gynecological pathology requires surgery in postmenopausal women, oophorectomy should be the preferred option. 相似文献
4.
5.
6.
Nursery Neurobiologic Risk Score: important factor in predicting outcome in very low birth weight infants 总被引:2,自引:0,他引:2
J E Brazy C O Eckerman J M Oehler R F Goldstein A M O'Rand 《The Journal of pediatrics》1991,118(5):783-792
We developed a nursery Neurobiologic Risk Score (NBRS) based on potential mechanisms of brain cell injury in preterm infants and correlated it with developmental outcome at the corrected ages of 6, 15, and 24 months. The NBRS was determined at 2 weeks of age and at the time of discharge from intensive care in 58 preterm infants with birth weights less than or equal to 1500 gm. The NBRS correlated significantly with the Bayley Scales of Infant Development, Mental Development Index (MDI) (r = -0.61 to -0.40) and Psychomotor Development Index (PDI) (r = -0.59 to -0.46), and with abnormal neurologic examination findings (r = 0.59 to 0.73) at the three testing periods. Although 12 of the 13 items composing the NBRS individually correlated with one or more outcome variables, seven items (infection, blood pH, seizures, intraventricular hemorrhage, assisted ventilation, periventricular leukomalacia, and hypoglycemia) accounted for almost all of the explained variance. Logistic regression of individual items demonstrated intraventricular hemorrhage to be the most important item for predicting the MDI at 24 months; pH was the most influential item for predicting the PDI at every testing period. A shorter, revised NBRS that included only the seven significant items demonstrated as strong a correlation with developmental outcome as the original NBRS. A revised 2-week score of greater than or equal to 5 or a discharge score of greater than or equal to 6 demonstrated 100% specificity and had a 100% positive predictive value for an abnormal outcome at 24 months of age in this group of infants. We conclude that the NBRS identifies during the intensive care nursery stay those infants at highest risk for an abnormal outcome related to nursery events. In addition, analysis of NBRS items provides insight into the relative importance of individual factors for influencing mental, motor, and neurologic outcome. 相似文献
7.
This study is based on the hypothesis of a paraventricular cerebral noradrenaline deficit in alcoholic Korsakoff's syndrome. In a randomized open study the effects of a 4-week treatment with the selective noradrenaline reuptake inhibitor reboxetine on (1) the salivary concentration of the noradrenaline metabolite MHPG and (2) changes in cognitive performance measured by the Mini Mental Status Test were examined. The study group consisted of 105 patients diagnosed with alcohol-related Korsakoff's syndrome (ICD-10: F10.6). Korsakoff's patients showed a reduced concentration of salivary MHPG compared to healthy controls; this reduction did not correlate with the results of the Mini Mental Status Test. An increase in salivary MHPG was found together with an improvement in the Mini Mental Status Test both in the verum group treated with reboxetine and in the control group upon completion of the 4-week study. However, a subgroup with a shorter duration of disease (<1 year) was found to profit significantly from reboxetine treatment, as shown by improvements in cognitive performance. 相似文献
8.
9.
Neuronal transmitter sensitivity after social isolation in rats 总被引:2,自引:0,他引:2
After 3 and 12 months of isolation rearing of rats, sensitivity of single neurons to microiontophoretically applied transmitters as well as neuronal spontaneous activity are analysed in striatum, cortex, hippocampus, locus coeruleus and nucleus raphis medialis. It is demonstrated that regulation of transmitter sensitivity, as well as spontaneous activity, depend on isolation duration, therefore showing time dynamics. Sensitivity changes of single neurons to distinct transmitters are not uniform and simultaneous in all areas but are structure specific. After 3 months of isolation an enhanced dopamine sensitivity is observed only in the striatum, whereas in the cortex the dopamine sensitivity is increased after 12 months isolation. A diminished response of single neuron activity to serotonin is demonstrable after 3 months of isolation in striatum and nucleus raphis. The observed changes are discussed in connection with biochemically and pharmacologically demonstrated changes in isolation. The complex patterns of neurobiological changes characterizing the isolation syndrome are emphasized. 相似文献
10.