全文获取类型
收费全文 | 695篇 |
免费 | 53篇 |
国内免费 | 6篇 |
专业分类
儿科学 | 19篇 |
妇产科学 | 11篇 |
基础医学 | 127篇 |
口腔科学 | 3篇 |
临床医学 | 34篇 |
内科学 | 120篇 |
皮肤病学 | 8篇 |
神经病学 | 18篇 |
特种医学 | 168篇 |
外科学 | 79篇 |
综合类 | 7篇 |
预防医学 | 126篇 |
眼科学 | 4篇 |
药学 | 20篇 |
肿瘤学 | 10篇 |
出版年
2022年 | 5篇 |
2021年 | 8篇 |
2020年 | 9篇 |
2019年 | 5篇 |
2018年 | 10篇 |
2017年 | 7篇 |
2016年 | 7篇 |
2015年 | 7篇 |
2014年 | 16篇 |
2013年 | 26篇 |
2012年 | 22篇 |
2011年 | 29篇 |
2010年 | 30篇 |
2009年 | 14篇 |
2008年 | 50篇 |
2007年 | 37篇 |
2006年 | 41篇 |
2005年 | 38篇 |
2004年 | 47篇 |
2003年 | 23篇 |
2002年 | 16篇 |
2001年 | 23篇 |
2000年 | 22篇 |
1999年 | 29篇 |
1998年 | 12篇 |
1997年 | 8篇 |
1996年 | 19篇 |
1995年 | 10篇 |
1994年 | 7篇 |
1993年 | 12篇 |
1992年 | 19篇 |
1991年 | 9篇 |
1990年 | 13篇 |
1989年 | 12篇 |
1988年 | 12篇 |
1987年 | 11篇 |
1986年 | 8篇 |
1985年 | 11篇 |
1984年 | 8篇 |
1983年 | 12篇 |
1982年 | 5篇 |
1981年 | 4篇 |
1980年 | 4篇 |
1979年 | 7篇 |
1974年 | 2篇 |
1973年 | 2篇 |
1972年 | 3篇 |
1970年 | 6篇 |
1969年 | 3篇 |
1956年 | 3篇 |
排序方式: 共有754条查询结果,搜索用时 31 毫秒
1.
2.
3.
The rate of heat storage mediates an anticipatory reduction in exercise intensity during cycling at a fixed rating of perceived exertion 总被引:8,自引:2,他引:6
Ross Tucker Trevor Marle Estelle V. Lambert Timothy D. Noakes 《The Journal of physiology》2006,574(3):905-915
The aim of the present study was to examine the regulation of exercise intensity in hot environments when exercise is performed at a predetermined, fixed subjective rating of perceived exertion (RPE). Eight cyclists performed cycling trials at 15°C (COOL), 25°C (NORM) and 35°C (HOT) (65% humidity throughout), during which they were instructed to cycle at a Borg rating of perceived exertion (RPE) of 16, increasing or decreasing their power output in order to maintain this RPE. Power output declined linearly in all three trials and the rate of decline was significantly higher in HOT than in NORM and COOL (2.35 ± 0.73 W min−1 , 1.63 ± 0.70 and 1.61 ± 0.80 W min−1 , respectively, P < 0.05). The rate of heat storage was significantly higher in HOT for the first 4 min of the trials only, as a result of increasing skin temperatures. Thereafter, no differences in heat storage were found between conditions. We conclude that the regulation of exercise intensity is controlled by an initial afferent feedback regarding the rate of heat storage, which is used to regulate exercise intensity and hence the rate of heat storage for the remainder of the anticipated exercise bout. This regulation maintains thermal homeostasis by reducing the exercise work rate and utilizing the subjective RPE specifically to ensure that excessive heat accumulation does not occur and cellular catastrophe is avoided. 相似文献
4.
BACKGROUND: While the bicycle frame and other parts of the bicycle have undergone many improvements, the bicycle saddle has remained relatively unchanged since it was first designed more than 100 years ago. Given the number and range of cycling injuries believed to result from the saddle, this is surprising. This study investigated the effects of a novel bicycle saddle on saddle-related comfort and symptoms during cycling. METHOD: Eleven competitive or recreational cyclists, 6 females and 5 males, performed three 2-hour stationary cycle rides in the laboratory, using their personal bicycles. Ride 1 was performed using the standard bicycle saddle and rides 2 and 3 using the novel bicycle saddle. Subjects reported saddle comfort rating scores (SC) while using the different saddles. Subjects also completed a questionnaire evaluating saddle symptoms (SS) when using either the conventional or the novel bicycle saddle during daily cycling. RESULTS: The most common saddle-related medical complaint with chronic use of the conventional saddle was painful pubic bones, with or without chaffing. Others were severe chaffing, saddle sores, chaffing and back pain, and painful pubic bones associated with a loss of feeling in the pelvic area. The mean SS rating score during the 2-hour laboratory ride was significantly less for the novel saddle (11.6 +/- 1.2 versus 19.1 +/- 3.2 arbitrary units, P < 0.01). Similarly the mean SC score was significantly lower for the novel saddle (36.2 +/- 10.5 v. 54.7 +/- 11.2 arbitrary units). Values for both SC scores were similar for rides 2 and 3. On completion of the trial all subjects indicated that they would continue to use the novel saddle in preference to the conventional saddle. Three months later 9 subjects (82%) reported continued use of this saddle in preference to the conventional saddle. CONCLUSION: These results show conclusively that this novel bicycle saddle: (i) significantly reduced reported symptoms during daily cycling compared with the conventionally designed cycling saddle; (ii) significantly improved saddle comfort during 2-hour cycles in the laboratory, such that (iii) when given the option the majority (82%) of the subjects chose to use this saddle 3 months later. Furthermore, the beneficial effects of the novel saddle were apparent during its first use, suggesting that the novel saddle is effective because the design is anatomically correct. 相似文献
5.
6.
7.
Daniel le Grange Jason Tibbs Timothy D. Noakes 《The International journal of eating disorders》1994,15(4):369-376
Competitive pressures to achieve a slim body shape may be of importance in the etiology of eating disorders in ballet dancers. This study examines the presence of anorexia nervosa-like symptoms in a group of 49 female ballet students (mean age = 18.9 years, SD ± 1.9). All students were assessed for certain physical (weight and height) and psychological (Eating Attitude Test [EAT]) indices at the start of their academic training year. Thereafter, all subjects who presented with anorexia nervosa-like symptoms (EAT ≥ 30, and/or with current secondary amenorrhea or primary amenorrhea if aged 16 years or over) at the initial assessment, were invited for a semistructured interview (Morgan-Russel scales) to determine their diagnostic status. Another aim of the study was to assess the prognostic implications of a diagnosis of anorexia nervosa in this sample. All subjects previously interviewed were invited for a follow-up assessment at 10 months. Anorexia nervosa could be diagnosed in 2 students (4.1%), whilst another 4 students (8.2%) presented with “partial syndrome” anorexia nervosa. All diagnosed students managed to complete their academic training year. The development and implications of a diagnosis of anorexia nervosa in the ballet students are discussed. 相似文献
8.
Genotype-phenotype correlation for nucleotide substitutions in the IgII- IgIII linker of FGFR2 总被引:6,自引:3,他引:3
9.
Kevin D. Derman John A. Hawley Timothy D. Noakes Steven C. Dennis 《European journal of applied physiology》1996,74(1-2):36-43
On two occasions, six well-trained, male competitive triathletes performed, in random order, two experimental trials consisting of either a timed ride to exhaustion on a cycle ergometer or a run to exhaustion on a motor-driven treadmill at 80% of their respective peak cycling and peak running oxygen (VO2max) uptakes. At the start of exercise, subjects drank 250 ml of a 15 g·100 ml–1 w/v [U-14C]glucose solution and, thereafter, 150 ml of the same solution every 15 min. Despite identical metabolic rates [VO2 3.51 (0.06) vs 3.51 (0.10) 1·min–1; values are mean (SEM) for the cycling and running trials, respectively], exercise times to exhaustion were significantly longer during cycling than running [96 (14) vs 63 (11) min; P < 0.05]. The superior cycling than running endurance was not associated with any differences in either the rate of blood glucose oxidation [3.8 (0.1) vs 3.9 (0.4) mmol· min–1], or the rate of ingested glucose oxidation [2.0 (0.1) vs 1.7 (0.2) mmol· min–1] at the last common time point (40 min) before exhaustion, despite higher blood glucose concentrations at exhaustion during running than cycling [7.0 (0.9) vs 5.8 (0.5) mmol·1–1; P < 0.05]. However, the final rate of total carbohydrate (CHO) oxidation was significantly greater during cycling than running [24.0 (0.8) vs 21.7 (1.4) mmol C6·min–1; P < 0.01]. At exhaustion, the estimated contribution to energy production from muscle glycogen had declined to similar extents in both cycling and running [68 (3) vs 65 (5)%]. These differences between the rates of total CHO oxidation and blood glucose oxidation suggest that the direct and/or indirect (via lactate) oxidation of muscle glycogen was greater in cycling than running. 相似文献
10.
John A. Hawley Steven C. Dennis Andrea Nowitz Fred Brouns Timothy D. Noakes 《European journal of applied physiology》1992,64(6):523-527
Summary Intestinal perfusion studies have shown that glucose absorption from maltose occurs faster than from isocaloric glucose. To determine whether ingested maltose might be a superior source of carbohydrate (CHO) for endurance athletes, we compared the rates of gastric emptying, absorption and oxidation of 15 g · 100 ml–1 solutions of maltose and glucose. Six endurance-trained cyclists drank 1200 ml of either U-14C maltose or U-14C glucose as a 400-ml loading bolus immediately before exercise, and as 8 × 100-ml drinks at 10-min intervals during a 90-min ride at 700% of maximal oxygen consumption. The rates of gastric emptying [maltose 690 (SD 119) ml · 90 min–1; glucose 655 (SD 93) ml · 90 min–1], the appearance of U-14C label in the plasma, and the peak rates of exogenous CHO oxidation [maltose 1.0 (SD 0.09) g · min–1; glucose 0.9 (SD 0.09) g · min–1] were not significantly different. Further, the 51 (SD 8) g of maltose and the 49 (SD 9) g of glucose oxidised during exercise were similar. Each accounted for approximately 2001o of the total CHO oxidised during the 90 min of exercise. Since only half of the CHO delivered to the intestine was oxidised in the 90-min ride (maltose 49%; glucose 50%), we conclude that neither the rate of gastric emptying, nor digestion limited the rate of ingested CHO utilisation during the early stages of exercise. Rather, we hypothesise that, initially, it could be the rate at which the CHO diffuses across the unstirred water layer of the brush-border of the intestinal villi that limits the utilisation of soluble CHO ingested during prolonged exercise. 相似文献