全文获取类型
收费全文 | 72200篇 |
免费 | 5032篇 |
国内免费 | 287篇 |
专业分类
耳鼻咽喉 | 879篇 |
儿科学 | 1717篇 |
妇产科学 | 1267篇 |
基础医学 | 9403篇 |
口腔科学 | 1105篇 |
临床医学 | 7077篇 |
内科学 | 15351篇 |
皮肤病学 | 1096篇 |
神经病学 | 6945篇 |
特种医学 | 2573篇 |
外国民族医学 | 14篇 |
外科学 | 12018篇 |
综合类 | 852篇 |
现状与发展 | 1篇 |
一般理论 | 74篇 |
预防医学 | 5764篇 |
眼科学 | 1378篇 |
药学 | 4480篇 |
中国医学 | 76篇 |
肿瘤学 | 5449篇 |
出版年
2023年 | 373篇 |
2022年 | 695篇 |
2021年 | 1621篇 |
2020年 | 896篇 |
2019年 | 1468篇 |
2018年 | 1785篇 |
2017年 | 1204篇 |
2016年 | 1358篇 |
2015年 | 1527篇 |
2014年 | 2352篇 |
2013年 | 3280篇 |
2012年 | 4842篇 |
2011年 | 5135篇 |
2010年 | 2869篇 |
2009年 | 2630篇 |
2008年 | 4449篇 |
2007年 | 4603篇 |
2006年 | 4441篇 |
2005年 | 4469篇 |
2004年 | 4296篇 |
2003年 | 3889篇 |
2002年 | 3748篇 |
2001年 | 576篇 |
2000年 | 458篇 |
1999年 | 655篇 |
1998年 | 833篇 |
1997年 | 694篇 |
1996年 | 629篇 |
1995年 | 594篇 |
1994年 | 527篇 |
1993年 | 478篇 |
1992年 | 414篇 |
1991年 | 427篇 |
1990年 | 351篇 |
1989年 | 350篇 |
1988年 | 320篇 |
1987年 | 308篇 |
1986年 | 286篇 |
1985年 | 322篇 |
1984年 | 494篇 |
1983年 | 429篇 |
1982年 | 555篇 |
1981年 | 522篇 |
1980年 | 510篇 |
1979年 | 268篇 |
1978年 | 307篇 |
1977年 | 297篇 |
1976年 | 229篇 |
1975年 | 224篇 |
1974年 | 249篇 |
排序方式: 共有10000条查询结果,搜索用时 0 毫秒
1.
2.
3.
Hanna Lee Mary K. Tan Andrew T. Yan Paul Angaran Paul Dorian Claudia Bucci Jean C. Gregoire Alan D. Bell Martin S. Green Peter L. Gross Allan Skanes Charles R. Kerr L. Brent Mitchell Jafna L. Cox Vidal Essebag Brett Heilbron Krishnan Ramanathan Carl Fournier Shaun G. Goodman 《The Canadian journal of cardiology》2019,35(2):160-168
Background
Physicians treating nonvalvular atrial fibrillation (AF) assess stroke and bleeding risks when deciding on anticoagulation. The agreement between empirical and physician-estimated risks is unclear. Furthermore, the association between patient and physician sex and anticoagulation decision-making is uncertain.Methods
We pooled data from 2 national primary care physician chart audit databases of patients with AF (Facilitating Review and Education to Optimize Stroke Prevention in Atrial Fibrillation and Coordinated National Network to Engage Physicians in the Care and Treatment of Patients with Atrial Fibrillation Chart Audit) with a combined 1035 physicians (133 female, 902 male) and 10,927 patients (4567 female and 6360 male).Results
Male physicians underestimated stroke risk in female patients and overestimated risk in male patients. Female physicians estimated stroke risk well in female patients but underestimated the risk in male patients. Risk of bleeding was underestimated in all. Despite differences in risk assessment by physician and patient sex, > 90% of patients received anticoagulation across all subgroups. There was modest agreement between physician estimated and calculated (ie, CHADS2 score) stroke risk: Kappa scores were 0.41 (0.35-0.47) for female physicians and 0.34 (0.32-0.36) for male physicians.Conclusions
Our study is the first to examine the association between patient and physician sex influences and stroke and bleeding risk estimation in AF. Although there were differences in agreement between physician estimated stroke risk and calculated CHADS2 scores, these differences were small and unlikely to affect clinical practice; further, despite any perceived differences in the accuracy of risk assessment by sex, most patients received anticoagulation. 相似文献4.
5.
6.
7.
Setting goals to maintain hope. 总被引:3,自引:0,他引:3
8.
Philippe Nickers Luc Coppens Jean de Leval Nicolas Jansen Jean-Marie Deneufbourg 《Radiotherapy and oncology》2006,79(3):329-334
BACKGROUND AND PURPOSE: To evaluate on 201 locally advanced prostatic cancers prospectively treated in a phase II trial, the efficacy of a combination of external beam radiotherapy (39.6 Gy) and (192)Ir low dose rate brachytherapy (Bt) (40-45 Gy). PATIENTS AND METHODS: Sixty-four patients were included in the intermediate prognosis group with only one of the following adverse factors (PSA > 10 ng/ml, Gleason score > or = 7 or clinical stage > or =T2b) and 137 in the unfavourable group when at least two of these factors were present. RESULTS: The actuarial 4 years biochemical no evidence of disease is 82.8% for the entire population. It is, respectively, 97 and 76% in the intermediate and unfavourable prognosis groups (P < 0.0001). Grade > or =3 late urinary complications occurred in 13 patients (6.5%). Eight patients (4%) presented late grade 2 rectal complications but no grades 3-5 was observed. CONCLUSIONS: Even if an alpha/beta of 1.5-3 Gy theoretically favours the use of a high dose rate mode of irradiation, the early results presented here are as good as those reported for similar groups of patients with high dose rate treatments. Late toxicity is identical but our urinary toxicity is within the less favourable and rectal toxicity within the most favourable results. We can postulate that while inducing very high hyperdosage regions (V150) mainly focused on the peripheral zone, most of the Bt techniques consist of a more ablative treatment. Many of the radiobiological studies on Bt did not in fact take into account the heterogeneity of irradiation inside the CTV. This study highlights the need to explore pulsed dose rate therapies, permanent implant and new available radioisotopes such as (169)Ytterbium that will offer the safety of low and lower dose rates. The actual late toxicity of the different Bt techniques is not yet inexistent indeed. 相似文献
9.
10.