全文获取类型
收费全文 | 6583篇 |
免费 | 386篇 |
国内免费 | 26篇 |
专业分类
耳鼻咽喉 | 74篇 |
儿科学 | 167篇 |
妇产科学 | 148篇 |
基础医学 | 940篇 |
口腔科学 | 271篇 |
临床医学 | 464篇 |
内科学 | 1587篇 |
皮肤病学 | 135篇 |
神经病学 | 461篇 |
特种医学 | 220篇 |
外科学 | 1044篇 |
综合类 | 61篇 |
预防医学 | 297篇 |
眼科学 | 62篇 |
药学 | 484篇 |
中国医学 | 14篇 |
肿瘤学 | 566篇 |
出版年
2023年 | 42篇 |
2022年 | 83篇 |
2021年 | 139篇 |
2020年 | 66篇 |
2019年 | 116篇 |
2018年 | 120篇 |
2017年 | 97篇 |
2016年 | 118篇 |
2015年 | 120篇 |
2014年 | 175篇 |
2013年 | 229篇 |
2012年 | 362篇 |
2011年 | 338篇 |
2010年 | 172篇 |
2009年 | 161篇 |
2008年 | 321篇 |
2007年 | 345篇 |
2006年 | 331篇 |
2005年 | 371篇 |
2004年 | 330篇 |
2003年 | 310篇 |
2002年 | 316篇 |
2001年 | 189篇 |
2000年 | 188篇 |
1999年 | 182篇 |
1998年 | 67篇 |
1997年 | 31篇 |
1996年 | 44篇 |
1994年 | 29篇 |
1993年 | 28篇 |
1992年 | 112篇 |
1991年 | 115篇 |
1990年 | 97篇 |
1989年 | 141篇 |
1988年 | 124篇 |
1987年 | 102篇 |
1986年 | 95篇 |
1985年 | 95篇 |
1984年 | 57篇 |
1983年 | 58篇 |
1981年 | 29篇 |
1980年 | 29篇 |
1979年 | 67篇 |
1978年 | 33篇 |
1977年 | 29篇 |
1975年 | 32篇 |
1973年 | 32篇 |
1969年 | 39篇 |
1968年 | 36篇 |
1966年 | 36篇 |
排序方式: 共有6995条查询结果,搜索用时 15 毫秒
1.
2.
Keiji Iwai 《Seishin shinkeigaku zasshi》2006,108(5):470-474
3.
Spinal antinociceptive effects of adenosine compounds in mice 总被引:1,自引:0,他引:1
The effects of injecting ATP, ADP, AMP, adenosine and adenine intrathecally on the pain response induced by the injection of substance P (10 ng/mouse) intrathecally were studied. All the compounds except adenine inhibited the pain response in a dose-related manner. The ED50 values of ATP, ADP, AMP and adenosine were 2.10, 0.93, 0.88 and 0.48 micrograms/mouse, respectively. Pretreatment with theophylline at a dose of 100 mg/kg p.o. markedly diminished all the antinociceptive effects. The effect of adenosine was not affected by s.c. injection of naloxone. These results suggest the existence of adenosine receptors which modulate spinal nociceptive sensory processing, independently of the endogenous opiate system. 相似文献
4.
5.
Tetsushi Tsujimoto Kazushi Daimon Kazuhide Izumi Maki Sawai Tatsuya Iwashige 《Seishin shinkeigaku zasshi》2007,109(4):313-320
Fifty two outpatients, who showed signs of school-refusal-withdrawal at the Shiga Prefectural Psychiatric Institution have been analyzed according to their age, gender, ICD-10 diagnosis, medical evolution, and total number of consultations. A total of 61.5% of the population were male, and they showed a higher average and a wider range of age than female patients. According to the ICD-10 diagnosis, 67.3% were in the group of F40-48 neurotic, stress-related and somatoform disorders, and 11.5% were in the group of F30-39 mood [affective] disorders. Twenty five % of the patients were assumed to have show medical improvement, and 42.3% of the patients continued to have further consultations. This article discusses the possible role of psychiatric medical institutions in supporting cases of school-refusal and social-withdrawal. 相似文献
6.
7.
The identification of atypical testicular germ cells is often difficult by by routine histologic examination. By immunohistochemical detection of placental alkaline phosphatase (PLAP) and by periodic acid Schiff staining of glycogen, atypical germ cells were easily identified in testicular samples. Forty-one fetal and adult testes were used for a preliminary study, and 121 testes from infants and adults with either cryptorchidism or germ cell tumors were studied for the presence of atypical germ cells. Two types of clear germ cells were differentiated histochemically, and one with PLAP-positive cell surfaces and glycogen-rich cytoplasm was considered to be atypical. The alkaline phosphatase of atypical germ cells appeared to be similar to that found in a few germ cells of early fetal testes. The atypical germ cells seemed to be multi-potential malignant cells capable of developing not only into seminoma but also into other germ cell tumors. Only in yolk sac tumor of infants were the atypical germ cells absent from tumor-adjacent seminiferous tubules. 相似文献
8.
Kohjirou Okahashi Kazuya Sugimoto Makoto Iwai Manabu Oshima Masayuki Samma Yoshiyuki Fujisawa Yoshinori Takakura 《Knee surgery, sports traumatology, arthroscopy》2006,14(6):542-545
The purpose of our study is to evaluate whether the hamstring tendons can regrow after harvesting for anterior cruciate ligament (ACL) reconstruction and whether the regenerate tissue can be histologically characterized as tendinous. Eleven of the patients (eight female and three male; mean age, 23 years; range 17–37 years) consented to participate in this study. One year after the ACL reconstruction, surgical biopsy was done. Regeneration of the tendon was detected macroscopically in 9 of the 11 patients. Histologically and immunohistochemically, the regenerated tendons closely resembled normal ones. The results of this study show the hamstring tendons can regenerate after harvesting for the ACL reconstruction. 相似文献
9.
Mitsuru Koizumi Yasuhiko Yamada Etsuji Nomura Maki Amano Yuji Okajima Hiromi Okizuka Keiko Yamada Seishi Sawano Takashi Kitahara Takashi Yamashita Minoru Nakane Toshio Ishikawa 《Annals of nuclear medicine》1995,9(2):101-104
A case of recurrent medullary thyroid cancer (MTC) was evaluated with123I-MIBG,99mTc(V)-dimercaptosuccinic acid (DMSA), and201Tl scintigraphy. This patient had been operated on for MTC in the right thyroid. Recently a left neck mass was noticed, and was suspected of being a. recurrence of MTC based on increased plasma calcitonin (CT) and carcinoembryonic antigen (CEA). He was operated on for the neck mass which revealed MTC, and papillary thyroid cancer was incidentally found in the left thyroid, but the CT and CEA levels remained high, and remaining MTC tumor was suspected. But the location of the tumor was unknown. Although99mTc(V)-DMSA scintigraphy is generally believed to be superior in sensitivity to123I-MIBG scintigraphy, it did not demonstrate the tumor site but201Tl and123I-MIBG did. Furthermore,123I-MEBG scintigraphy has greater specificity for tumors which arise in the neural crest. Judging from the results of this case and cases reported in the literatures, both123I-MIBG and99mTc(V)-DMSA should be performed in the detection of recurrent MTC. 相似文献
10.
B F Trump T W Jones K A Elliget M W Smith P C Phelps A Maki I K Berezesky 《Renal failure》1990,12(3):183-191
Cellular toxicity and cellular carcinogenesis are closely linked. In the kidney, this relationship has been emphasized by the recent discovery of a number of putatively non-mutagenic chemicals that result in acute and chronic toxicity and ultimately in carcinogenesis, especially in the male rat. Many, but not all such compounds, result in renal PTE phagolysosomal overload. At the same time, known metabolites of other carcinogens, e.g., HCBD and FBPA, result in acute renal injury and/or necrosis, followed by chronic tubular disease, interstitial nephritis, and ultimately carcinogenesis. A series of cell mechanisms have been suggested that lead from acute cell injury to altered control of cell division. These mechanisms appear to involve ion deregulation, (especially [Ca2+]i) resulting from a variety of continued injuries, (e.g., oxidative stress from inflammatory cells) and ultimately leading to altered gene expression. 相似文献