全文获取类型
收费全文 | 3039篇 |
免费 | 279篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 44篇 |
儿科学 | 88篇 |
妇产科学 | 93篇 |
基础医学 | 534篇 |
口腔科学 | 124篇 |
临床医学 | 242篇 |
内科学 | 582篇 |
皮肤病学 | 39篇 |
神经病学 | 244篇 |
特种医学 | 92篇 |
外科学 | 326篇 |
综合类 | 32篇 |
一般理论 | 2篇 |
预防医学 | 321篇 |
眼科学 | 84篇 |
药学 | 237篇 |
中国医学 | 50篇 |
肿瘤学 | 195篇 |
出版年
2023年 | 27篇 |
2022年 | 51篇 |
2021年 | 111篇 |
2020年 | 64篇 |
2019年 | 81篇 |
2018年 | 107篇 |
2017年 | 69篇 |
2016年 | 83篇 |
2015年 | 79篇 |
2014年 | 125篇 |
2013年 | 128篇 |
2012年 | 207篇 |
2011年 | 187篇 |
2010年 | 103篇 |
2009年 | 101篇 |
2008年 | 144篇 |
2007年 | 159篇 |
2006年 | 149篇 |
2005年 | 145篇 |
2004年 | 138篇 |
2003年 | 137篇 |
2002年 | 109篇 |
2001年 | 67篇 |
2000年 | 79篇 |
1999年 | 91篇 |
1998年 | 25篇 |
1997年 | 20篇 |
1996年 | 19篇 |
1995年 | 15篇 |
1994年 | 19篇 |
1993年 | 18篇 |
1992年 | 41篇 |
1991年 | 37篇 |
1990年 | 34篇 |
1989年 | 39篇 |
1988年 | 34篇 |
1987年 | 24篇 |
1986年 | 25篇 |
1985年 | 17篇 |
1984年 | 20篇 |
1983年 | 21篇 |
1982年 | 8篇 |
1981年 | 8篇 |
1974年 | 9篇 |
1973年 | 11篇 |
1971年 | 10篇 |
1970年 | 13篇 |
1969年 | 12篇 |
1966年 | 12篇 |
1965年 | 9篇 |
排序方式: 共有3329条查询结果,搜索用时 15 毫秒
1.
Predictors of clustering of tuberculosis in Greater Vancouver: a molecular epidemiologic study 总被引:3,自引:0,他引:3
下载免费PDF全文
![点击此处可从《Canadian Medical Association journal》网站下载免费的PDF全文](/ch/ext_images/free.gif)
2.
3.
F. M. González Valverde F. Mauri Barberá M. Molto Aguado N. Torregrosa A. Hernández Quiles F. Menárguez Pina M. J. Gómez Ramos M. García Real J. A. Barreras Mateos J. L. Vázquez Rojas 《European Surgery》2004,36(4):253-256
Summary BACKGROUND: Endometriosis is a relatively common pathology in women of childbearing age and of low parity but rarely shows
extraperitoneal involvement. The main aim of this paper is to raise the attention of specialists to the necessity of carrying
out penetrating diagnosis of nonspecific extraperitoneal masses occurring in women of reproductive age. METHODS: We performed
a retrospective review of six patients diagnosed with extraperitoneal endometriosis who were treated at the Vega Baja University
Hospital (Spain) during the last 5 years. RESULTS: Surgical treatment had positive results in five patients. The preoperative
diagnosis was correctly made in only two patients. The accurate aetiology of endometriosis remains unknown and diagnosis is
based on clinical and cytopathological findings. CONCLUSIONS: Surgical treatment of extraperitoneal endometriosis is recommended.
However, postoperative follow-up is obligatory and hormonal suppressive therapy may be necessary. Medical treatment with gestagens,
Danazol, or agonists of the gonadotropin-releasing hormone are ineffective in endometriomas which are bigger than 2 cm.
相似文献
4.
5.
6.
H Sasano Y Saito H Nagura R Kudo M Rojas S G Silverberg 《International journal of gynecological pathology》1991,10(3):252-259
The lectin-binding properties of 44 cases of serous and mucinous ovarian cystadenoma, tumor of low malignant potential (LMP), and invasive carcinoma were examined histochemically. Wheat germ agglutinin (WGA), concanavalin A (con A), Ulex europaeus agglutinin I (UEA-I), peanut agglutinin (PNA), Ricinus communis agglutinin I (RCA-I), soybean agglutinin (SBA), and Robina pseudoaccacia (RPA) were employed. All the lectins examined were bound to neoplastic epithelial cells of benign and malignant tumors, but none bound exclusively to ovarian tumor cells. Different lectin-binding patterns between serous and mucinous neoplasms were observed, with the exception of RPA. UEA-I, con A, RPA, and PNA in serous neoplasms and UEA-I, RPA, and WGA in mucinous neoplasms demonstrated lectin-binding properties of LMP tumors intermediate between those of cystadenoma and invasive carcinoma. These findings indicate that serous and mucinous ovarian neoplasms contain different glycoconjugates, that malignant transformation of the neoplasms is associated with alteration of these glycoconjugates, and especially that LMP tumors have a different composition of cellular glycoconjugates from that of invasive ovarian carcinoma. 相似文献
7.
G Falero I Rodríguez J Sarracent A J Otero B L Rodríguez A Rojas E Ochoa 《Hybridoma》1992,11(6):815-823
We report the generation of murine triomas by fusing splenocytes from mice previously immunized with HBsAg ay-subtype and a hybridoma, secreting anti-HBsAg ad-subtype monoclonal antibody, which was rendered HGPRT- by induced mutagenesis with N-methyl-N'nitro-N-nitrosoguanidine. The fusion yielded a 83.8% of hybrids showing the antigen specificity of the parental hybridoma and a 16.1% of bi-specific monoclonal antibodies. One of them, coded as 1C8A5, showing a heavy chain isotype (IgG1/IgG2b) was used as capture reagent in an ultramicro-ELISA. As little as 0.78 I.U. of both HBsAg ad- and ay-subtypes could be realiably detected. 相似文献
8.
A. Rojas R. J. Hodgkiss M. R. Stratford M. F. Dennis H. Johns 《British journal of cancer》1993,68(6):1115-1121
Plasma concentrations, after administration of varying doses of nicotinamide, were measured in CBA male mice using a newly-developed high performance liquid chromatography assay. In all dose groups, peak levels were observed within the first 15 min after an i.p. administration of 0.1, 0.2, 0.3 or 0.5 mg g-1 of nicotinamide. There was a clear dose-dependent increase in plasma concentration with increasing dose, with almost a five-fold lower concentration (1.0 vs 4.9 mumol ml-1) achieved with a dose of 0.1 mg g-1 compared with 0.5 mg g-1, respectively. The half-life of nicotinamide increased from 1.4 h to 2.2 h over the dose range (P < 0.01). Comparisons with previous pharmacokinetic data in humans show that clinically-relevant oral doses of 6 and 9 g in humans give plasma levels slightly higher than those achieved at 1 h with doses of 0.1 to 0.2 mg g-1 in mice. Tumour radiosensitisation with carbogen alone, and with carbogen combined with varying doses of nicotinamide (0.05 to 0.5 mg g-1), was investigated using a 10-fraction in 5 days X-ray schedule. Relative to air-breathing mice, a statistically significant increase in sensitisation was observed with both a local tumour control and with an in vivo/in vitro excision assay (P < or = 0.007). With the local control assay, a trend was observed towards lower enhancement ratios (ERs) with decreasing nicotinamide dose (from 1.85 to 1.55); carbogen alone was almost as effective as when combined with 0.1 mg g-1 of nicotinamide. With the excision assay, ERs for carbogen combined with nicotinamide increased with decreased levels of cell survival. At a surviving fraction of 0.02, enhancement ratios of 1.39-1.48 were obtained for carbogen plus 0.1 to 0.3 mg g-1 of nicotinamide. These were lower than those seen with the two higher doses of 0.4 to 0.5 mg g-1 (ERs = 1.63-1.69). 相似文献
9.
C Rojas 《Zeitschrift für Gerontologie》1986,19(2):122-124
Two selected homes for the elderly in Lima, Perú, are described with particular consideration of infrastructure, conceptions, inhabitants, equipment and regulations. Some results of a preliminary study concerning life and behavior of the inhabitants are given. 相似文献
10.