全文获取类型
收费全文 | 5601篇 |
免费 | 449篇 |
国内免费 | 78篇 |
专业分类
耳鼻咽喉 | 54篇 |
儿科学 | 232篇 |
妇产科学 | 84篇 |
基础医学 | 750篇 |
口腔科学 | 166篇 |
临床医学 | 627篇 |
内科学 | 1126篇 |
皮肤病学 | 127篇 |
神经病学 | 482篇 |
特种医学 | 542篇 |
外科学 | 673篇 |
综合类 | 170篇 |
一般理论 | 1篇 |
预防医学 | 473篇 |
眼科学 | 91篇 |
药学 | 254篇 |
2篇 | |
中国医学 | 1篇 |
肿瘤学 | 273篇 |
出版年
2022年 | 37篇 |
2021年 | 90篇 |
2020年 | 48篇 |
2019年 | 81篇 |
2018年 | 94篇 |
2017年 | 83篇 |
2016年 | 84篇 |
2015年 | 102篇 |
2014年 | 136篇 |
2013年 | 194篇 |
2012年 | 222篇 |
2011年 | 220篇 |
2010年 | 179篇 |
2009年 | 178篇 |
2008年 | 192篇 |
2007年 | 257篇 |
2006年 | 229篇 |
2005年 | 217篇 |
2004年 | 175篇 |
2003年 | 150篇 |
2002年 | 151篇 |
2001年 | 147篇 |
2000年 | 157篇 |
1999年 | 149篇 |
1998年 | 175篇 |
1997年 | 197篇 |
1996年 | 162篇 |
1995年 | 144篇 |
1994年 | 139篇 |
1993年 | 124篇 |
1992年 | 96篇 |
1991年 | 108篇 |
1990年 | 107篇 |
1989年 | 129篇 |
1988年 | 123篇 |
1987年 | 106篇 |
1986年 | 112篇 |
1985年 | 95篇 |
1984年 | 63篇 |
1983年 | 45篇 |
1982年 | 51篇 |
1981年 | 46篇 |
1980年 | 46篇 |
1979年 | 32篇 |
1978年 | 41篇 |
1977年 | 41篇 |
1976年 | 45篇 |
1975年 | 27篇 |
1974年 | 27篇 |
1972年 | 24篇 |
排序方式: 共有6128条查询结果,搜索用时 15 毫秒
1.
Chronic pain in the UK affects up to 43% of the population. The consequences include physical and psychological distress, loss of function, employment, family and social strain and increased utilization of healthcare services. Modern pain management services operate across primary, secondary and tertiary care and incorporate general practitioners, psychologists, physiotherapists, pharmacists, specialist nurses, pain physicians and surgeons. This allows for a coordinated approach to chronic pain, engaging the patient in a structured pathway from conservative measures, through to surgery if necessary. Surgical interventions have been utilized effectively throughout the 20th century for the treatment of a variety of conditions, some of which are now effectively managed with improved pharmacological approaches or novel neuromodulation techniques. Ablative procedures that aim to permanently interrupt the pain pathway still represent the final solution for some conditions, particularly those with cancer associated pain; however, the search for less invasive, less risky measures continues. This is stimulated by an increased understanding of the neurobiology of pain transmission and the physiological changes which occur in persistent pain. 相似文献
2.
JM Martín† L Calduch† C Monteagudo‡ I Molina† D Ramón† V Alonso† E Jordᆠ《Journal of the European Academy of Dermatology and Venereology》2006,20(4):428-431
Cutaneous plasmacytosis is a rare disorder characterized by a benign proliferation of mature plasma cells that appears as multiple dark-brown to purplish skin lesions, often associated with polyclonal hypergammaglobulinaemia. We present the case of a 55-year-old Caucasian man who suffered from a cutaneous plasmacytosis associated with two different carcinomas. Cutaneous plasmacytosis seems to be a reactive process because most cases reported are not associated with any apparent underlying disease. Nevertheless, because few reported cases were associated with malignancies, screening of additional neoplasms would be justified. 相似文献
3.
D. Chattar-Cora R. Perez-Nieves A. McKinlay M. Kunasz R. C. Lyons 《European journal of plastic surgery》2007,29(5):221-226
Free tissue transfer has been demonstrated to be an effective modality of treating a variety of wounds and conditions in the
civilian population. The use of these procedures has been underreported by American military surgeons. Military surgeons face
unique hurdles that make the effective performance of these procedures difficult. We report our experience with free flap
reconstruction at an American Army medical center. We performed 44 free flaps in 38 patients; although operative times and
hospital length of stay were comparatively long, our success rates were excellent with only one partial flap loss.
The opinions or assertions contained herein are the private views of the authors and are not to be construed as official or
reflecting the views of the Department of the Army or the Department of Defense. 相似文献
4.
5.
Management of dislocations of both ends of the clavicle 总被引:2,自引:0,他引:2
J O Sanders F A Lyons C A Rockwood 《The Journal of bone and joint surgery. American volume》1990,72(3):399-402
We treated six patients who had a dislocation of both ends of the clavicle (an anterior dislocation of the sternoclavicular joint and a posterior dislocation of the acromioclavicular joint). Two patients who had fewer demands on the shoulder--an elderly woman and a woman who had had an ipsilateral amputation of the hand--did well; they had only minor symptoms after non-operative management. The other four patients (all men) had continuing pain at the acromioclavicular joint; each had a reconstruction of the joint, which resulted in a painless, full range of motion and return to normal activity. No patient had continuing pain in the sternoclavicular joint. 相似文献
6.
JM Vilanova J Figueras-Aloy J Roselló G Gómez E Gelpí R Jiménez 《Acta paediatrica (Oslo, Norway : 1992)》1998,87(5):588-592
The aim of this study was to evaluate the cerebral synthesis of eicosanoids in the asphyctic newborn and to investigate the relation between the prostanoid profiles in cerebrospinal fluid (CSF) and the appearance and severity of hypoxic-ischaemic encephalopathy (HIE). Levels of 6-keto-PGF 1-α, TXB2 , PGE2 and PGF2-α in CSF were measured in 40 full term newborns during the first day of life. Thirty of these newborns had birth asphyxia and were divided into three groups: 10 without HIE, 12 with mild HIE and 8 with moderate-severe HIE. They were compared to a control group of 10 non-hypoxic newborns. Determinations of the metabolites in CSF were performed by RIA and expressed as pg/ml (mean ± SD). The CSF TXB2 (thromboxane A2 metabolite) in asphyxiated newborns was always higher than in the control group (28.12 ± 10.6), and related to the severity of HIE ( p = 0:005): without HIE (50.84 ± 16.4; p = 0:02), mild HIE (80.65 ± 12.64; p ± 0:01) and moderate-severe HIE (178.14 ± 20.5; p < 0:01). The CSF 6-keto-PGF 1-α (prostacyclin metabolite) in asphyxiated newborns was always higher than in the control group (80.55 ± 12.56), but indirectly related to the severity of HIE: without HIE (240.95 ± 28.12; p < 0:01), mild HIE (183.65 ± 30.1; p < 0:01) and moderate-severe HIE (140.55 ± 25.12; p < 0:01). In the moderate-severe HIE group, the increase in TXB2 was higher than the rise in 6-keto-PGF 1-α . 相似文献
7.
Wendy E. Marshman MD FRACO Christopher J. Lyons FRCS 《Clinical & experimental ophthalmology》1998,26(2):161-163
Purpose: To highlight an unusual organism causing a unilateral endophthalmitis by transplacental spread.
Method: We report a case of Plesiomonas shigelloides endophthalmitis, presenting in a newborn, with co-existing septicaemia and meningitis. There was a significant maternal history of diarrhoea associated with the ingestion of oysters 2 weeks prior to delivery.
Result: The endophthalmitis was treated with parenteral antibiotics and topical mydriatics with complete resolution, although subsequent assessment of the affected eye suggests a poor visual outcome.
Conclusion: Endophthalmitis in the newborn is an unusual clinical finding and usually presents with other manifestations of bacteraemia. Plesiomonas shigelloides is fortunately an infrequent cause of neonatal infection, but is associated with a high degree of morbidity and mortality. We postulate that this neonate acquired P. shigelloides via the transplacental route, and suggest that this organism be included in the list of 'other' causes of transplacental infection that has been abbreviated to 'O' in the acronym TORCH. 相似文献
Method: We report a case of Plesiomonas shigelloides endophthalmitis, presenting in a newborn, with co-existing septicaemia and meningitis. There was a significant maternal history of diarrhoea associated with the ingestion of oysters 2 weeks prior to delivery.
Result: The endophthalmitis was treated with parenteral antibiotics and topical mydriatics with complete resolution, although subsequent assessment of the affected eye suggests a poor visual outcome.
Conclusion: Endophthalmitis in the newborn is an unusual clinical finding and usually presents with other manifestations of bacteraemia. Plesiomonas shigelloides is fortunately an infrequent cause of neonatal infection, but is associated with a high degree of morbidity and mortality. We postulate that this neonate acquired P. shigelloides via the transplacental route, and suggest that this organism be included in the list of 'other' causes of transplacental infection that has been abbreviated to 'O' in the acronym TORCH. 相似文献
8.
9.
10.