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排序方式: 共有196条查询结果,搜索用时 15 毫秒
1.
D St-Vil F I Luks B J Hancock L Garel P Brochu H Blanchard A L Bensoussan 《Journal of pediatric surgery》1992,27(10):1301-1303
Gallbladder anomalies are rare and normally affect its shape, size, and position. We report on a 3-year-old boy with a gallbladder divided transversally by a windsock-type diaphragm, isolating the fundus from the rest of the biliary tree. Bilobed and multiseptated gallbladder have been described before, but this is the first isolated case of a congenital hourglass gallbladder. 相似文献
2.
Complications of lymphangiomas in children. 总被引:8,自引:0,他引:8
B J Hancock D St-Vil F I Luks M Di Lorenzo H Blanchard 《Journal of pediatric surgery》1992,27(2):220-4; discussion 224-6
One hundred ninety-three cases of lymphangioma presenting in children were reviewed over a 10-year period. The diagnosis was established before 5 years of age in 87.0%. The distribution of lymphangiomas was: cervical (31.4%), craniofacial (18.9%), extremity (18.9%), trunk (9.2%), intraabdominal (9.2%), cervicoaxillothoracic (4.9%), multiple (3.8%), cervicomediastinal (2.2%), and intrathoracic (1.6%). Of 164 patients undergoing primary therapy, total excision was performed in 77.4% and partial excision in 20.7% with recurrence rates of 11.8% and 52.9%, respectively. Thirty-eight percent of all operations for lymphangiomas were performed for resection of recurrent or residual disease. The incidence of postoperative complications was 31.3%. Forty-four additional procedures were required to manage these complications. Sclerotherapy with 50% dextrose was used as an adjunct in 9.5%. Recurrences were seen after total resection in 17.6% of operations in which 50% dextrose was used and 11.8% in which it was not used. Seroma formation was noted in 3.5% of total resections and 40.0% of resections for recurrent disease in which adjunctive sclerotherapy with 50% dextrose was used. Seromas occurred in 9.8% of wounds in which local drains were used and 3.6% of wounds in which drains were not used. Infectious complications occurred after 6.6% of operations using perioperative antibiotics and 3.5% not using antibiotics. The management of lymphangiomas in children remains a difficult problem. Despite being benign lesions, lymphangiomas are attended by a high rate of morbidity from complications of the disease and its management. Complete excision still offers the best chance for complete cure. Sclerotherapy with 50% dextrose is not beneficial in the management of recurrent disease or postoperative seromas. Local drains and perioperative antibiotics do not appear to diminish the incidence of seromas and infectious complications, respectively. 相似文献
3.
M. E. De Paepe Konstantinos Papadakis Brian D. Johnson Francois I. Luks 《Virchows Archiv : an international journal of pathology》1998,432(1):7-16
Tracheal occlusion in utero has been shown to cause accelerated fetal lung growth and is now being considered as a therapeutic
modality for pulmonary hypoplasia. We report the effects of tracheal ligation on the surfactant-producing type II pneumocyte
population. Three groups of fetal lambs underwent tracheal ligation of 2 weeks’, 4 weeks’ and 6 weeks’ duration, respectively,
and all were sacrificed at 136 days’ gestation (9 days pre-term). Nonoperated twins served as controls. The type II pneumocyte
population was studied morphometrically using a combination of anti-surfactant protein B immunohistochemistry and computer-assisted
stereologic morphometry at light and electron microscopic levels. Single-factor ANOVA was used for statistical analysis. Two
weeks of tracheal ligation resulted in doubling of the total lung volume as a result of airspace distension and, to lesser
extent, growth of the tissue compartment. With increasing duration of tracheal ligation, there was no additional lung growth.
However, more prolonged tracheal occlusion was found to result in significant reduction of the surfactant system, as reflected
in the marked decrease of total pneumocyte type II volume (3.14 cm3, 0.95 cm3, and 0.46 cm3, after 2, 4, and 6 weeks of ligation, compared with 5.96 cm3 for controls) and total pneumocyte type II number (13.9 × 109, 3.8 × 109, and 2.4 × 109, compared with 53.2 × 109 for controls). Ultrastructural analysis of the type II cells in obstructed lungs showed vacuolar degenerative changes that,
after 6 weeks of ligation, were apparently irreversible. In utero tracheal ligation causes fetal lung hyperplasia, but results
in reduction of and injury to the surfactant-producing cell population. Before tracheal occlusion can find widespread clinical
application, its pathophysiology needs to be further elucidated.
Received: 30 April 1997 / Accepted: 10 July 1997 相似文献
4.
The impact of hydrosalpinx (HSPX) on in-vitro fertilization (IVF) outcome
has recently been the subject of intense debate. Most, but not all, studies
have reported decreased implantation and pregnancy rates and increased
early pregnancy loss in HSPX patients. This has led to prophylactic
salpingectomies prior to IVF in HSPX patients despite the lack of any
prospective studies to suggest that any improvement will occur. Women with
HSPX constitute a heterogeneous population because some conceive easily
with IVF while others do not until after surgical correction. HSPX also
increases in size with ovarian stimulation, and can cause implantation
failure by fluid reflux into the uterine cavity. Careful assessment of the
endometrial lining is mandatory in HSPX to rule out fluid reflux from the
HSPX. We present two case reports of patients whose HSPX enlarged with
ovarian stimulation, causing fluid reflux into the uterine cavity which was
only noted after human chorionic gonadotrophin (HCG) administration.
相似文献
5.
S. Levchuck G. Luks E. Eshaghpour P. Anisman L. Marks B. Robinson 《Pediatric cardiology》1995,16(2):85-86
Percutaneous balloon dilatation angioplasty is a common therapeutic modality in patients with congenital heart disease. We report three cases of the catheter sheath telescoping into the hub of the sheath after removal of the balloon catheter. Although initially it appeared as though the sheath was torn, in actuality it was intact. We report this problem so others can avoid needless searching and concern for the missing catheter tip. 相似文献
6.
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9.
T E Borton B L Nolen S B Luks N C Meline 《Audiology : official organ of the International Society of Audiology》1989,28(2):61-70
Insert transducers for audiometry are available which may offer significant advantages over older 'standard' headphones. Clinicians have remained cautious in using such devices due to the paucity of experimental data demonstrating their comparability with more widely used devices. The purpose of this investigation was to compare and contrast pure-tone audiometric thresholds obtained using insert earphones with those measured utilizing conventional supra-aural transducers in normal and hearing-impaired subjects. A second purpose was to examine the differential effects on the hearing threshold level of two coupling systems for the insert device. There were no clinically significant differences among pure-tone thresholds measured with the three earphone/coupler arrangements for subjects with normal and impaired hearing. Advantages and limitations of insert earphones are discussed. 相似文献
10.
The glyoxylate cycle, which is well characterized in higher plants and some microorganisms but not in vertebrates, is able
to bypass the citric acid cycle to achieve fat-to-carbohydrate interconversion. In this context, the hydrodynamic transfer
of two glyoxylate cycle enzymes, such as isocytrate lyase (ICL) and malate synthase (MS), could accomplish the shift of using
fat for the synthesis of glucose. Therefore, 20 mice weighing 23.37 ± 0.96 g were hydrodinamically gene transferred by administering
into the tail vein a bolus with ICL and MS. After 36 hours, body weight, plasma glucose, respiratory quotient and energy expenditure
were measured. The respiratory quotient was increased by gene transfer, which suggests that a higher carbohydrate/lipid ratio
is oxidized in such animals. This application could help, if adequate protocols are designed, to induce fat utilization for
glucose synthesis, which might be eventually useful to reduce body fat depots in situations of obesity and diabetes. 相似文献