全文获取类型
收费全文 | 3696篇 |
免费 | 254篇 |
国内免费 | 88篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 181篇 |
妇产科学 | 109篇 |
基础医学 | 588篇 |
口腔科学 | 70篇 |
临床医学 | 454篇 |
内科学 | 846篇 |
皮肤病学 | 152篇 |
神经病学 | 196篇 |
特种医学 | 337篇 |
外国民族医学 | 2篇 |
外科学 | 405篇 |
综合类 | 40篇 |
预防医学 | 213篇 |
眼科学 | 68篇 |
药学 | 187篇 |
中国医学 | 1篇 |
肿瘤学 | 169篇 |
出版年
2021年 | 31篇 |
2020年 | 18篇 |
2019年 | 51篇 |
2018年 | 49篇 |
2017年 | 42篇 |
2016年 | 42篇 |
2015年 | 52篇 |
2014年 | 78篇 |
2013年 | 127篇 |
2012年 | 120篇 |
2011年 | 159篇 |
2010年 | 133篇 |
2009年 | 110篇 |
2008年 | 134篇 |
2007年 | 179篇 |
2006年 | 129篇 |
2005年 | 142篇 |
2004年 | 127篇 |
2003年 | 150篇 |
2002年 | 128篇 |
2001年 | 99篇 |
2000年 | 97篇 |
1999年 | 97篇 |
1998年 | 109篇 |
1997年 | 113篇 |
1996年 | 132篇 |
1995年 | 102篇 |
1994年 | 94篇 |
1993年 | 94篇 |
1992年 | 81篇 |
1991年 | 81篇 |
1990年 | 62篇 |
1989年 | 75篇 |
1988年 | 80篇 |
1987年 | 70篇 |
1986年 | 72篇 |
1985年 | 61篇 |
1984年 | 39篇 |
1983年 | 40篇 |
1982年 | 45篇 |
1981年 | 45篇 |
1980年 | 42篇 |
1979年 | 24篇 |
1978年 | 20篇 |
1977年 | 22篇 |
1976年 | 30篇 |
1975年 | 20篇 |
1973年 | 13篇 |
1972年 | 14篇 |
1971年 | 16篇 |
排序方式: 共有4038条查询结果,搜索用时 15 毫秒
1.
Catecholaminergic polymorphic ventricular tachycardia is important to be diagnosed as an underlying disease in children with syncope and normal heart, because of its poor prognosis. CASE REPORT: A 3-year-old boy was referred for stress and emotion induced syncope. Primary ventricular arrhythmia, consisting of salvos of bidirectional ventricular tachycardia, was reproducibly induced by physical exertion. The syncopal events and severe arrhythmia disappeared with beta-blocking therapy. CONCLUSION: Despite its rare occurrence, catecholaminergic polymorphic ventricular tachycardia is an important cause of stress and emotion induced syncope and sudden death in children. 相似文献
2.
3.
4.
5.
In a limited group of open angle glaucoma patients treated twice daily with timoptol 0.5% and having by this treatment a mean intra-ocular pressure of 21-22 mmHg, the association of timoptol 0.5% with pilocarpine 2% respectively, lowered the intra-ocular pressure to an average of 17.8 mmHg and 16.6 mmHg after one and three weeks of continuous treatment. For this study, the patients have been divided into 3 groups: A group treated with timoptol 0.5% alone throughout the 49 days of the study. A group treated with timoptol 0.5%-pilocarpine 2% (timpilo 2) from day 21 to day 49. A final group treated with timoptol 0.5% until day 21 and then with timoptol 0.5%-pilocarpine 4% (timpilo 4) through out day 49. These patients stopped the treatment before the end of the study. Intra-ocular pressures were measured on days 0, 21 and 49. We found a higher drop of pressure (-4.8 mmHg) in the timpilo 2 group than in the timoptol 0.5% group (-1 mmHg) before instillation as well as 2 hours afterwards (-5.25 mmHg and -2 mmHg respectively). The secondary local effects were due to miotics agents. The secondary systemic effects were those inherent to beta-blockers. These results are comparable with a multicentric study of 220 patients, therefore statistically significant. 相似文献
6.
Differential anti-influenza activity among allelic variants at the Sus scrofa Mx1 locus. 总被引:1,自引:0,他引:1
M Palm M Leroy A Thomas A Linden D Desmecht 《Journal of interferon & cytokine research》2007,27(2):147-155
A promising way to oppose infectious challenges would be to improve the resistance of the target species through genetic selection. Theoretically, a candidate gene is available against influenza viruses since a resistance trait was fortuitously discovered in the A2G mouse strain. This trait was demonstrated to be correlated with the expression of a specific isoform of the type I interferon (IFN)-dependent protein MX, an isoform coded by a specific allele at the mouse Mx1 locus. Two allelic polymorphisms were described recently in the Sus scrofa homologous gene. In this study, the frequencies and distribution of both alleles were evaluated among European domestic pig and wild boar populations by PCR-RFLP, and the anti-influenza activity conferred by both MX1 isoforms was evaluated in vitro using transfection of Vero cells followed by flow cytometric determination of the fraction of influenza virus-infected cells among MX-producing and MX-nonproducing cell populations. A significant difference in the anti-influenza activity brought by the two MX1 isoforms was demonstrated, which suggests that a significant improvement of innate resistance of pigs by genetic selection might be feasible provided the differences found here in vitro are epidemiologically relevant in vivo. 相似文献
7.
8.
9.
10.
F. Picard E. Montbarbon Y. Tourne J. M. Leroy D. Saragaglia 《International orthopaedics》1997,21(5):352-354
Summary. A pseudo-tumour due to metallosis is described in association with an iso-elastic hip replacement. This is a relatively rare
lesion which may be difficult to diagnose. Scintigraphy and radiography may be helpful in distinguishing the lesion from a
primary or secondary neoplasm, but the presence of osteolysis adjacent to the prosthesis will suggest the true nature of the
lesion.
Accepted: 29 February 1996 相似文献
Résumé. Les auteurs rapportent un cas de manifestation pseudo-tumorale d’une métallose sur prothèse de hanche de type iso-élastique. Il s’agit d’une lésion relativement rare qui peut parfois avoir un aspect inquiétant. Elle nécessite un bilan radiologique et scintigraphique pour éliminer une tumeur primitive ou secondaire, mais le diagnostic est facilement évoqué devant une ostéolyse au contact de la prothèse. Nous décrirons notre démarche diagnostique et thérapeutique dans ce cas.
Accepted: 29 February 1996 相似文献