全文获取类型
收费全文 | 616篇 |
免费 | 111篇 |
国内免费 | 11篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 14篇 |
妇产科学 | 12篇 |
基础医学 | 72篇 |
口腔科学 | 5篇 |
临床医学 | 59篇 |
内科学 | 115篇 |
皮肤病学 | 4篇 |
神经病学 | 25篇 |
特种医学 | 75篇 |
外科学 | 115篇 |
综合类 | 11篇 |
一般理论 | 2篇 |
预防医学 | 14篇 |
眼科学 | 5篇 |
药学 | 136篇 |
中国医学 | 1篇 |
肿瘤学 | 70篇 |
出版年
2023年 | 4篇 |
2022年 | 5篇 |
2021年 | 9篇 |
2020年 | 9篇 |
2019年 | 8篇 |
2018年 | 8篇 |
2017年 | 9篇 |
2016年 | 7篇 |
2015年 | 12篇 |
2014年 | 18篇 |
2013年 | 26篇 |
2012年 | 23篇 |
2011年 | 9篇 |
2010年 | 9篇 |
2009年 | 22篇 |
2008年 | 22篇 |
2007年 | 30篇 |
2006年 | 22篇 |
2005年 | 11篇 |
2004年 | 33篇 |
2003年 | 19篇 |
2002年 | 12篇 |
2001年 | 18篇 |
2000年 | 15篇 |
1999年 | 15篇 |
1998年 | 15篇 |
1997年 | 24篇 |
1996年 | 13篇 |
1995年 | 15篇 |
1994年 | 23篇 |
1993年 | 24篇 |
1992年 | 22篇 |
1991年 | 25篇 |
1990年 | 19篇 |
1989年 | 18篇 |
1988年 | 13篇 |
1987年 | 12篇 |
1986年 | 21篇 |
1985年 | 23篇 |
1984年 | 26篇 |
1983年 | 14篇 |
1982年 | 16篇 |
1981年 | 6篇 |
1980年 | 7篇 |
1979年 | 4篇 |
1978年 | 4篇 |
1976年 | 4篇 |
1975年 | 6篇 |
1974年 | 2篇 |
1971年 | 2篇 |
排序方式: 共有738条查询结果,搜索用时 15 毫秒
1.
2.
Primary squamous cell carcinoma is an extremely rare tumour of the thyroid gland. A case of an elderly lady who was diagnosed to have primary squamous cell carcinoma of the thyroid gland is presented and the role of radiotherapy is discussed. 相似文献
3.
Hilde Tobi Paul B. van den Berg Lolkje TW de Jong‐van den Berg 《Pharmacoepidemiology and drug safety》2006,15(3):211-211
The original article to which this Erratum refers was published in Pharmacoepidemiology and Drug Safety 2005; 14: 239–247. 相似文献
4.
5.
K R Clark J L Forsythe K M Rigg J Sharp L Rangecroft J Wagget N R Parrott T W Lennard M G Coulthard 《Journal of pediatric surgery》1992,27(6):780-783
Since 1982 eight patients under 1 year of age with end-stage renal failure have been treated by chronic peritoneal dialysis (CPD) following insertion of an abdominal Tenckhoff catheter. We routinely perform a partial omentectomy now, and in males undertake bilateral exploration of the groins at the time of catheter insertion, with herniotomy or ligation of the patent processus vaginalis as required. Up to January 1990, 19 straight double-cuff catheters had been inserted with a total follow-up of 244.5 patient months. The median age at the initial catheter insertion was 14.6 weeks (range, 2 days to 11 months) and the median weight was 3.89 kg (range, 2.2 to 5.5). Peritonitis was the most common complication, with 46 episodes, representing one episode of peritonitis per 5.3 patient months on dialysis. The frequency of peritonitis has decreased in the last 6 months since all patients have been dialysed by two caregivers. The present rate of peritonitis is 1 episode per 10 patient months on dialysis. One patient has died of septicemia secondary to associated congenital abnormalities, one patient has regained renal function, and two patients have been transplanted, one successfully. Five patients are currently dialysing via their abdominal Tenckhoff catheters and awaiting transplantation. We conclude that neonates and infants under 1 year of age can be treated satisfactorily by CPD to enable successful preparation for transplantation later in childhood. 相似文献
6.
7.
N R Parrott T W Lennard R M Taylor G Proud B K Shenton I D Johnston 《The British journal of surgery》1986,73(12):970-973
The aim of the present study was to examine the outcome of 517 patients undergoing curative surgery for colonic and rectal cancer, and to compare the recurrence and mortality rates in transfused and non-transfused groups of patients. The two groups were evenly matched for age, sex, Dukes' stage and histological differentiation. There were significantly more rectal tumours in the transfused group (P less than 0.01), but the distribution of colonic lesions did not differ. Life table analysis revealed that the transfused patients had a 20 per cent greater probability of recurrence at 5 years (P less than 0.005) and there were 16 per cent more cancer related deaths (P less than 0.01). Even when all rectal cancers were excluded, a similar trend was seen for the colonic lesions: a 24 per cent greater probability of recurrence at 5 years (P less than 0.025) and 15 per cent more cancer related deaths (P less than 0.02). We conclude that blood transfusion may be associated with increased mortality and recurrence in patients undergoing curative surgery for colorectal cancer. 相似文献
8.
Periosteal Ewing sarcoma 总被引:3,自引:0,他引:3
9.
Mehrotra P Okpokam A Bouhaidar R Johnson SJ Wilson JA Davies BR Lennard TW 《Histopathology》2004,45(5):493-500
AIMS: To determine whether galectin-3 is a sensitive indicator of thyroid malignancy. It has been suggested as a potential marker for differentiating thyroid carcinoma from benign or non-neoplastic lesions in preoperative fine-needle aspirates (FNAs). METHODS: Galectin-3 protein expression was assessed by immunohistochemistry in formalin-fixed thyroid tissues from 124 patients with histological diagnoses of papillary carcinoma (n = 38), follicular carcinoma (n = 19), follicular adenoma (n = 32) and dominant nodules of multinodular goitre (n = 35). Expression of galectin-3 was also assessed by Western blotting in 24 fresh thyroid tissues. RESULTS: Galectin-3 expression was observed in the majority of carcinomas (papillary 92%; follicular 74%). However, a large proportion of follicular adenomas (72%) and multinodular goitres (57%) also expressed galectin-3. In addition, galectin-3 expression was observed in epithelial cells of normal thyroid tissue and Hashimoto's thyroiditis. Galectin-3 immunopositivity was significantly greater in papillary carcinomas than in dominant nodules or follicular adenomas (P < 0.0001, P = 0.0005, respectively). However, galectin-3 expression was no greater in follicular carcinomas than in follicular adenomas (P = 0.8735). Western blotting analysis confirmed both the specificity of the antiserum and expression of galectin-3 in multinodular goitres, follicular adenomas/carcinomas and papillary carcinomas. CONCLUSION: The data demonstrate that galectin-3 is not a reliable immunohistochemical marker to distinguish benign from malignant thyroid follicular lesions. 相似文献
10.
An indirect immunoperoxidase (IP) slide test was evaluated for the laboratory identification of Bacteroides fragilis. Antigen-antibody complexes were detected with goat anti-rabbit immunoglobulin G-peroxidase conjugate with 3-amino-9-ethyl-carbazole as the peroxidase substrate. Ninety-one percent of 44 B. fragilis strains tested were IP positive (3+ to 4+ reactions) with greater than or equal to 1:160 dilutions of rabbit antiserum produced against whole cells of B. fragilis ATCC 23745. The antiserum was species specific. No cross-reactions were observed with 35 Bacteroides strains of other species or with a variety of facultative or aerobic gram-negative bacilli. Four B. fragilis strains were IP negative. One of these (VPI 2393) was the deoxyribonucleic acid (DNA) homology group II reference strain. The other three were clinical isolates. IP-negative and representative IP-positive strains were tested for DNA homology with the type strains for DNA homology groups I and II (VPI 2553 and VPI 2393). Two of the three clinical isolates were classified as DNA homology group II, and the remaining strain was classified as a group I. Capsular material known to be unique to B. fragilis was common to both DNA homology groups as indicated by reactions with purified anticapsular antiserum. The IP technique provides a suitable alternative to fluorescent microscopy for the rapid immunological identification of B. fragilis. 相似文献