全文获取类型
收费全文 | 3768篇 |
免费 | 193篇 |
国内免费 | 18篇 |
专业分类
耳鼻咽喉 | 41篇 |
儿科学 | 112篇 |
妇产科学 | 129篇 |
基础医学 | 565篇 |
口腔科学 | 90篇 |
临床医学 | 306篇 |
内科学 | 686篇 |
皮肤病学 | 92篇 |
神经病学 | 275篇 |
特种医学 | 75篇 |
外科学 | 407篇 |
综合类 | 26篇 |
一般理论 | 3篇 |
预防医学 | 602篇 |
眼科学 | 104篇 |
药学 | 212篇 |
中国医学 | 22篇 |
肿瘤学 | 232篇 |
出版年
2024年 | 3篇 |
2023年 | 46篇 |
2022年 | 110篇 |
2021年 | 183篇 |
2020年 | 99篇 |
2019年 | 165篇 |
2018年 | 172篇 |
2017年 | 122篇 |
2016年 | 113篇 |
2015年 | 120篇 |
2014年 | 181篇 |
2013年 | 221篇 |
2012年 | 311篇 |
2011年 | 354篇 |
2010年 | 203篇 |
2009年 | 175篇 |
2008年 | 258篇 |
2007年 | 222篇 |
2006年 | 187篇 |
2005年 | 170篇 |
2004年 | 143篇 |
2003年 | 104篇 |
2002年 | 91篇 |
2001年 | 31篇 |
2000年 | 15篇 |
1999年 | 17篇 |
1998年 | 15篇 |
1997年 | 18篇 |
1996年 | 9篇 |
1995年 | 7篇 |
1994年 | 9篇 |
1993年 | 7篇 |
1992年 | 13篇 |
1991年 | 4篇 |
1990年 | 4篇 |
1989年 | 8篇 |
1988年 | 4篇 |
1987年 | 8篇 |
1985年 | 3篇 |
1984年 | 7篇 |
1983年 | 4篇 |
1982年 | 4篇 |
1981年 | 4篇 |
1979年 | 4篇 |
1976年 | 3篇 |
1974年 | 4篇 |
1967年 | 2篇 |
1965年 | 3篇 |
1944年 | 2篇 |
1934年 | 2篇 |
排序方式: 共有3979条查询结果,搜索用时 15 毫秒
1.
2.
Eloise R. Galligan Leila H. Shayegan Christine T. Lauren Kimberly D. Morel 《Pediatric dermatology》2019,36(5):753-754
Shaving and other modes of epilation can cause undue anxiety, pain, or skin irritation in children. Here, we present hair trimming as a safe, painless, and cost‐effective alternative for patients with unwanted hair which may be performed indefinitely or until the child is old enough to direct management. In select cases, removing unwanted hair using this technique may facilitate dermatologic surveillance. 相似文献
3.
Shinichiro Uchiyama Takao Hoshino Leila Sissani Monteiro Tavares Linsay Kenji Kamiyama Taizen Nakase Kazuo Kitagawa Kazuo Minematsu Kenichi Todo Yasushi Okada Jyoji Nakagawara Ken Nagata Hiroshi Yamagami Takenori Yamaguchi Pierre Amarenco 《Journal of stroke and cerebrovascular diseases》2019,28(8):2232-2241
BackgroundTIAregistry.org is an international cohort of patients with transient ischemic attack (TIA) or minor stroke within 7 days before enrollment in the registry. Main analyses of 1-year follow-up data have been reported.5 We conducted subanalysis on the baseline and 1-year follow-up data of Japanese patients.MethodsThe patients were classified into 2 groups based on Japanese ethnicity, Japanese (345) and non-Japanese (3238), and their baseline data and 1-year event rates were compared. We also determined risk factors and predictors of 1-year stroke.ResultsCurrent smoking, regular alcohol drinking, intracranial arterial stenosis, and small vessel occlusion; and hypertension, dyslipidemia, coronary artery disease, and extracranial arterial stenosis were more and less common among Japanese patients, respectively. Stroke risk was higher and TIA risk was lower at 1-year follow-up among Japanese patients. The baseline risk factors for recurrent stroke were diabetes, alcohol drinking, and large artery atherosclerosis. Independent predictors of 1-year stroke risk were prior congestive heart failure and alcohol consumption.ConclusionsThe two populations of patients featured differences in risk factors, stroke subtypes, and outcome events. Predictors of recurrent stroke among Japanese patients included congestive heart failure and regular alcohol drinking. Strategies to attenuate residual risk of stroke aside from adherence to current guidelines should take our Japanese-patient specific findings into account. 相似文献
4.
Christophe Meyer Leila Serhir Philippe Boutemi 《Journal of cranio-maxillo-facial surgery》2006,34(3):173-181
INTRODUCTION: The purpose of the study is to evaluate experimentally the quality of the primary stability achieved in treating low subcondylar fractures by means of three different osteosynthesis devices. MATERIAL AND METHODS: The devices, a standard four-hole plate, an axial lag screw and a three-dimensional rectangular plate were tested on fresh isolated human mandibles. Testing was done on a test bench by reproducing static biting exercises between the first molars on the side of the fracture. The quality of the osteosynthesis was assessed by measuring the macroscopic amount of fragment displacement and on the device's ability to diffuse the mechanical strain within the fractured area by photoelastic stress analysis. RESULTS: The straight plates provided the worst restoration. This was explained by the unfavourable position of the plate along compression lines. The axial lag screws allowed average stability. This was due to the difficulty of intra-medullary positioning of the screw, and by the compression of the fracture line. Rectangular plates allowed good stability associated with rather good restitution of the strains. These good results were assigned to the shape of the plate, one of its arms approximating the tensile strain lines. CONCLUSION: Positioning and shape of the osteosynthesis device are of prime importance for condylar fracture stabilization. None of the three tested devices was optimal but the three-dimensional plate was the best. There is a need to develop the geometry of new plates. 相似文献
5.
6.
Milena Soares Santos Guilherme de Sousa Ribeiro Tainara Queiroz Oliveira Renan Cardoso Nery Santos Edilane Gouveia Kátia Salgado Daniele Takahashi Cleuber Fontes Leila Carvalho Campos Mitermayer Galvão Reis Albert Icksang Ko Joice Neves Reis 《International journal of infectious diseases》2009,13(4):456-461
7.
Gisela Gamboa Philip M. Carpenter M.D. Yale D. Podnos Guillermo Dorion M.D. Leila Iravani Denis Bolton James T. Mascarello Ph.D. Alberto Manetta M.D. 《Gynecologic oncology》1995,58(3)
We introduce a new epithelial ovarian carcinoma cell line (UCI 107) from a patient with papillary adenocarcinoma of the ovary who had not been previously treated. The growth characteristics, chemosensitivity, tumorgenicity, cytogenetics, antigen expression, and receptor status were examined. A standardized photometric assay was implemented to determine the response to single drug agents including doxorubicin (ADR), cisplatin (CDDP), and Taxol. Tumorgenicity was determined utilizing female athymic mice implanted either subcutaneously (sc) or intraperitoneally (ip) with 1 × 107 UCI 107 cells. UCI 107 cells grow rapidly in culture with lag phase of approximately 48 hr, population doubling time of 24-36 hr, and saturation density of 4.8 × 105 cells/cm2. The 50% inhibitory concentration values for the chemotherapeutic agents were 0.170, 0.029, and 0.330 μM for ADR, Taxol, and CDDP, respectively. Nude mice produced ip tumors within 15 days, resulting in death from carcinomatosis 40-45 days postimplantation. Subcutaneous tumor nodules (100 mm3 were observed in nude mice 12-13 days post-tumor implantation reaching a maximum tumor volume of approximately 10,000 mm3 by Day 30. The cytogenetic composite karyotype is as follows: 46, X, der (X) t (X;7) (p11;q22), inv dup (1) (q12;q32), t (6;6;11;22) (p21.3;q16;q23.3;q13.3), del (13) (q14.1). The cell line expresses progesterone receptor, increased levels of p53 protein, and cytokeratins. It does not appear to express Her-2/neu protein, estrogen receptor, nor the CA 125 tumor marker. In conclusion, UCI 107 displays unique cellular properties which make it an attractive model for the study of ovarian cancer. 相似文献
8.
Three-dimensional reconstruction in routine computerized tomography of the skull and spine. Experience based on 161 cases. 总被引:1,自引:0,他引:1
L Bonnier K Ayadi A Vasdev G Crouzet B Raphael 《Journal of neuroradiology. Journal de neuroradiologie》1991,18(3):250-266
Three-dimensional (3D) reconstruction in routine computerized tomography (CT) presupposes that the referring clinicians are motivated, software programs are of good quality, a second working console is available and manipulations are made by experienced persons. Maxillofacial surgery is the main, conventional indication, but the method is also used to plan the surgical treatment of craniofacial malformations and that of injuries and tumours. 3D reconstruction cannot replace a thorough analysis of the acquisition sections since its spatial definition is not as good as theirs. Without competing with pure research-work, a number of applications remain in the realm of speculative imaging, but it cannot be denied that 3D reconstruction has an interesting potential for teaching. 相似文献
9.
10.
H Skouri H Soua B Seket H Elomri K Mounastiri A Ayadi M N Gueddiche M T Sfar P Bierling 《Archives de pédiatrie》2003,10(10):887-890
Alloimmune thrombocytopenia is due to feto-maternal incompatibility in the HPA systems and is usually considered in the diagnosis of neonatal thrombocytopenia after other causes have been excluded. We report on two Tunisian observations of alloimmune neonatal thrombocytopenia due to anti-HPA-5b (Bra) antibodies. CASE REPORT: Two neonates presented at birth with a thrombocytopenic purpura unexplained by usual causes of neonatal thrombocytopenia. Alloimmune neonatal thrombocytopenia was diagnosed by the determination of parental and neonatal platelets antigens phenotypes and by the presence of HPA-5b (antiBra) antibodies in maternal sera. A favourable evolution was obtained after maternal platelet transfusions. CONCLUSION: Alloimmune neonatal thrombocytopenia is a serious affection, which exposes to intracranial haemorrhage. These observations of HPA-5 neonatal alloimmunisation in Tunisia provide additional information on the geographic distribution of the disease and its prognosis. 相似文献