全文获取类型
收费全文 | 1989篇 |
免费 | 99篇 |
国内免费 | 13篇 |
专业分类
耳鼻咽喉 | 5篇 |
儿科学 | 144篇 |
妇产科学 | 19篇 |
基础医学 | 192篇 |
口腔科学 | 55篇 |
临床医学 | 262篇 |
内科学 | 481篇 |
皮肤病学 | 24篇 |
神经病学 | 116篇 |
特种医学 | 227篇 |
外科学 | 241篇 |
综合类 | 38篇 |
预防医学 | 67篇 |
眼科学 | 17篇 |
药学 | 104篇 |
1篇 | |
中国医学 | 1篇 |
肿瘤学 | 107篇 |
出版年
2021年 | 22篇 |
2019年 | 30篇 |
2018年 | 36篇 |
2017年 | 19篇 |
2016年 | 19篇 |
2015年 | 27篇 |
2014年 | 40篇 |
2013年 | 53篇 |
2012年 | 66篇 |
2011年 | 69篇 |
2010年 | 67篇 |
2009年 | 64篇 |
2008年 | 63篇 |
2007年 | 32篇 |
2006年 | 45篇 |
2005年 | 45篇 |
2004年 | 32篇 |
2003年 | 46篇 |
2002年 | 50篇 |
2001年 | 37篇 |
2000年 | 39篇 |
1999年 | 47篇 |
1998年 | 97篇 |
1997年 | 93篇 |
1996年 | 97篇 |
1995年 | 62篇 |
1994年 | 62篇 |
1993年 | 52篇 |
1992年 | 36篇 |
1991年 | 43篇 |
1990年 | 29篇 |
1989年 | 53篇 |
1988年 | 50篇 |
1987年 | 50篇 |
1986年 | 33篇 |
1985年 | 55篇 |
1984年 | 33篇 |
1983年 | 23篇 |
1982年 | 23篇 |
1981年 | 24篇 |
1980年 | 15篇 |
1978年 | 18篇 |
1977年 | 14篇 |
1976年 | 21篇 |
1975年 | 15篇 |
1973年 | 16篇 |
1971年 | 19篇 |
1969年 | 14篇 |
1967年 | 12篇 |
1966年 | 12篇 |
排序方式: 共有2101条查询结果,搜索用时 125 毫秒
1.
PJ Commerford 《Cardiovascular journal of Africa》2015,26(4):151-Aug;26(4):151
2.
Hans Bosma Martin PJ van Boxtel Gertrudis IJM Kempen Jacques ThM van Eijk Jelle Jolles 《BMC public health》2007,7(1):179
Background
The aims of this study were to examine the extent to which higher intellectual abilities protect higher socio-economic groups from functional decline and to examine whether the contribution of intellectual abilities is independent of childhood deprivation and low birth weight and other socio-economic and developmental factors in early life. 相似文献3.
4.
5.
Previous reports in the literature have described correlation of increasing repeat length with severity of the phenotype, in Kennedy syndrome. We describe male siblings with different repeat lengths, with lack of expression of the phenotype in the sibling with the longer repeat length. The phenotype was identical to motor neurone disease. There is variability of expression in Kennedy syndrome and repeat length even in siblings cannot be taken as a conclusive indicator of severity. CAG repeat length cannot be used to predict the natural history of Kennedy disease. The diagnosis of Kennedy syndrome should be considered in male patients presenting with atypical motor neurone disease. 相似文献
6.
PJ Woll PhD MRCP R Pettengell PhD FRACP 《International journal of clinical practice》1997,51(2):111-115
SUMMARY The interferons are natural glycoproteins secreted in response to various stimuli, including viral infection. They have antiviral, antiproliferative and immunomodulatory effects on different target cell populations. Since recombinant human interferons have become available, they have been tested in a wide range of malignancies. They are well established in the treatment of hairy cell leukaemia, chronic myelogenous leukaemia and multiple myeloma. Although they have documented activity against lymphoma, melanoma, renal cell cancer and carcinoid tumours, their role in the treatment of these tumours is less clear. In the common solid tumours, such as lung cancer and colorectal cancer, the use of interferons remains experimental. Here we will summarise their practice applications in oncology, using randomised studies where available to establish their place in multi-modality treatment. We will not discuss their use as antiviral or immunomodulating agents in viral and autoimmune diseases, multiple sclerosis or after organ transplantation. 相似文献
7.
P Damas A Adam J Buret C Renard M Lamy J B Foidart P Mahieu 《European journal of clinical investigation》1987,17(2):166-173
An enzyme-linked immunoassay has been recently set up for direct measurement of the binding capacity of plasma fibronectin to gelatin. This binding capacity could be completely inhibited in vitro by an eight-fold excess of gelatin, of Haemaccel, but not of Geloplasma. On the contrary, the levels of immunoreactive fibronectin measured by laser nephelometry did not change, in presence of 10 to 1000 micrograms ml-1 of gelatin, of Haemaccel or of Geloplasma. When infused into normal volunteers, Haemaccel provoked a strong and immediate inhibition of the plasma fibronectin binding capacity to gelatin. This inhibition was dose-dependent and maximal after infusion of 500 ml of Haemaccel. Twenty-four hours after this infusion, there was a progressive recovery of the gelatin-binding capacity, which was almost completely achieved 96 h later. The formation of complexes between Haemaccel and fibronectin was demonstrated by gel filtration chromatography and by affinity chromatography. Immunoreactive plasma fibronectin levels remained unchanged up to 24 h after infusion of 500 ml of Haemaccel. A transient decline to 50% of its initial value then occurred the second day after the infusion. Therefore, a delay existed between the formation of fibronectin-Haemaccel complexes and their elimination from the bloodstream. This delay decreased when smaller volumes of Haemaccel were infused, which strongly suggests that plasma fibronectin is cleared by means of Haemaccel and does not seem to play a role of opsonin in these conditions.(ABSTRACT TRUNCATED AT 250 WORDS) 相似文献
8.
9.
Percutaneous balloon dilatation of calcific aortic valve stenosis: anatomical and haemodynamic evaluation. 总被引:2,自引:2,他引:0
下载免费PDF全文
![点击此处可从《Heart (British Cardiac Society)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
P Commeau G Grollier E Lamy J P Foucault C Durand G Maffei D Maiza A Khayat J C Potier 《Heart (British Cardiac Society)》1988,59(2):227-238
Two groups of elderly patients with calcified aortic stenosis were treated by balloon dilatation. In group 1, the valve was dilated just before surgical replacement of the valve. The valvar and annular changes occurring during dilatation were examined visually. In 20 of the 26 patients in this group there was no change. In the six remaining patients mobilisation of friable calcific deposits (1 case), slight tearing of the commissure (4 cases), or tearing of the aortic ring (1 case) were seen. Dilatation did not appear to alter valvar rigidity. In 14 patients (group 2) the haemodynamic gradient across the aortic valve was measured before and immediately after dilatation and one week after the procedure. Dilatation produced an immediate significant decrease of the aortic mean gradient and a significant increase of the aortic valve area. Eight days later the mean gradient had increased and the aortic valve area had decreased. Nevertheless there was a significant difference between the initial gradient and the gradient eight days after dilatation. The initial aortic valve area was also significantly larger than the area eight days after dilatation. The aortic valve gradient rose significantly in the eight days after dilatation and at follow up the gradients were those of severe aortic stenosis. 相似文献
10.