全文获取类型
收费全文 | 220篇 |
免费 | 3篇 |
国内免费 | 1篇 |
专业分类
耳鼻咽喉 | 2篇 |
妇产科学 | 2篇 |
基础医学 | 87篇 |
临床医学 | 19篇 |
内科学 | 39篇 |
神经病学 | 5篇 |
外科学 | 4篇 |
预防医学 | 11篇 |
眼科学 | 6篇 |
药学 | 30篇 |
肿瘤学 | 19篇 |
出版年
2022年 | 3篇 |
2021年 | 3篇 |
2019年 | 3篇 |
2018年 | 3篇 |
2017年 | 2篇 |
2016年 | 2篇 |
2015年 | 5篇 |
2014年 | 3篇 |
2013年 | 2篇 |
2012年 | 2篇 |
2011年 | 5篇 |
2010年 | 5篇 |
2009年 | 3篇 |
2008年 | 5篇 |
2007年 | 4篇 |
2006年 | 3篇 |
2005年 | 7篇 |
2004年 | 4篇 |
2003年 | 9篇 |
2002年 | 5篇 |
2001年 | 6篇 |
2000年 | 11篇 |
1999年 | 6篇 |
1993年 | 3篇 |
1992年 | 6篇 |
1991年 | 8篇 |
1990年 | 2篇 |
1989年 | 7篇 |
1988年 | 8篇 |
1987年 | 4篇 |
1986年 | 6篇 |
1985年 | 4篇 |
1984年 | 4篇 |
1983年 | 3篇 |
1982年 | 2篇 |
1981年 | 2篇 |
1980年 | 2篇 |
1979年 | 7篇 |
1978年 | 6篇 |
1976年 | 6篇 |
1975年 | 3篇 |
1974年 | 7篇 |
1973年 | 4篇 |
1972年 | 2篇 |
1971年 | 5篇 |
1969年 | 7篇 |
1968年 | 2篇 |
1967年 | 3篇 |
1966年 | 3篇 |
1965年 | 3篇 |
排序方式: 共有224条查询结果,搜索用时 359 毫秒
1.
2.
3.
4.
Lankin VZ Sherenesheva NI Konovalova GG Tikhaze AK 《Bulletin of experimental biology and medicine》2000,130(7):694-696
The effects of pretreatment with β-carotene-containing preparation carinat on the development of renal tumors in rats receiving
single intravenous injection of chemical carcinogen 3-(1-α-L-arabinopyranosyl)-1-methyl-1-nitrosourea were studied. Fourteen
months after carcinogen administration, the degree of lipid oxidation in rat kidneys 2.5-fold surpassed that in animals receiving
carinat in a dose producingin vivo antioxidant effect. Carinat decreased the total number of induced tumors and the incidence of mesenchymal renal tumors and
suppressed the development of multiple tumors. The accumulation of lipoperoxides in the kidneys during carcinogenesis is associated
with activation of free radical processes and carcinogen-induced inhibition of lipoperoxide enzymatic degradation and probably
promotes renal malignancies due to co-carcinogenic action of these compounds. The data suggest that carinat-induced suppression
of tumor development attests to antioxidant effects of β-carotene.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 130, No. 7, pp. 95–97, July, 2000 相似文献
5.
V. P. Tverdokhlib G. G. Konovalova V. Z. Lankin F. Z. Meerson 《Bulletin of experimental biology and medicine》1988,106(5):1526-1528
All-Union Cardiologic Scientific Center, Academy of Medical Sciences of the USSR. Research Institute of General Pathology and Pathological Physiology, Academy of Medical Sciences of the USSR, Moscow. Grenburg Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR I. K. Shkhvatsabaya.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 106, No. 11, pp. 528–529, November, 1988. 相似文献
6.
Sedankin M. K. Gudkov A. G. Vesnin S. G. Konovalova A. A. Leushin V. Yu. Solov’ev Yu. V. Sidorov I. A. Agasieva S. V. Chizhikov S. V. Gorlacheva E. N. 《Biomedical engineering》2021,55(3):224-228
Biomedical Engineering - We present here an analytical review of technical means used for intracavity thermometry of biological objects. Radiometers can be effective both in medicine and veterinary... 相似文献
7.
Lankin VZ Ivanova MV Konovalova GG Tikhaze AK Kaminnyi AI Kukharchuk VV 《Bulletin of experimental biology and medicine》2007,143(4):414-417
We studied the effects of two inhibitors of β-hydroxy-β-methylglutaryl coenzyme A reductase, simvastatin and lovastatin, on
the lag phase of ascorbate-dependent lipid oxidation in rat liver. Oxidizability of liver biological membranes significantly
increased in intact animals and rats with induced hypercholesterolemia after peroral administration of these statins. The
lag phase of ascorbate-dependent lipid oxidation in liver biomembranes decreased by 2.1 times in hypercholesterolemic rats.
In animals of the lovastatin group this parameter decreased by 4.4 times compared to the control. In intact rats receiving
simvastatin, the lag phase of oxidation in biomembranes from the liver decreased practically by 2 times. At the same time,
in animals receiving simvastatin in combination with antioxidant vitamins (vitamins E and C, provitamin A) and selenium, the
period of induction of oxidation increased by 3.3 times. Our results indicate that β-hydroxy-β-methylglutaryl coenzyme A reductase
inhibitors produce a prooxidant effect on the liver, which can be prevented by administration of antioxidant agents.
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 4, pp. 390–393, April, 2007 相似文献
8.
Lakomkin VL Kapel'ko VI Lankin VZ Konovalova GG Kaminnyi AI 《Bulletin of experimental biology and medicine》2007,143(4):408-410
Long-term administration of β-hydroxy-β-methylglutaryl coenzyme A reductase inhibitor atorvastatin to rats was accompanied
by an increase in the relative weight of the heart and decrease in the rate of pressure development in the isovolumic heart.
During oxidative stress induced by addition of 100 μM H2O2 to the perfusate, the decrease in contractile function was more pronounced that in the control. Our results indicate that
administration of atorvastatin is accompanied by a decrease in myocardial contractility, which becomes more pronounced under
conditions of oxidative stress.
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 143, No. 4, pp. 383–385, April, 2007 相似文献
9.
Kaminnyi AI Lankin VZ Perepelitsa EI Konovalova GG Samko AN Tikhaze AK Kukharchuk VV Belenkov YN 《Bulletin of experimental biology and medicine》2007,144(5):664-666
Low-dose (250 mg daily) oral probucol produces a significant antioxidant effect in coronary patients: increases activity of
glutathione peroxidase (enzyme utilizing lipoperoxides) and reduces the content of free-radical oxidation products in the
blood. Probucol therapy for 7 days before and for 6 months after coronary angioplasty significantly reduces the severity of
coronary artery stenosis.
__________
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 11, pp. 503–506, November, 2007 相似文献
10.
Balzhima Shagdarova Mariya Konovalova Yuliya Zhuikova Alexey Lunkov Vsevolod Zhuikov Dolgor Khaydapova Alla Ilina Elena Svirshchevskaya Valery Varlamov 《Materials》2022,15(1)
Diabetes mellitus continues to be one of the most common diseases often associated with diabetic ulcers. Chitosan is an attractive biopolymer for wound healing due to its biodegradability, biocompatibility, mucoadhesiveness, low toxicity, and hemostatic effect. A panel of hydrogels based on chitosan, collagen, and silver nanoparticels were produced to treat diabetic wounds. The antibacterial activity, cytotoxicity, swelling, rheological properties, and longitudinal sections of hydrogels were studied. The ability of the gels for wound healing was studied in CD1 mice with alloxan-induced diabetes. Application of the gels resulted in an increase in VEGF, TGF-b1, IL-1b, and TIMP1 gene expression and earlier wound closure in a comparison with control untreated wounds. All gels increased collagen deposition, hair follicle repair, and sebaceous glands formation. The results of these tests show that the obtained hydrogels have good mechanical properties and biological activity and have potential applications in the field of wound healing. However, clinical studies are required to compare the efficacy of the gels as animal models do not reproduce full diabetes pathology. 相似文献