全文获取类型
收费全文 | 458572篇 |
免费 | 74172篇 |
国内免费 | 26098篇 |
专业分类
耳鼻咽喉 | 4411篇 |
儿科学 | 9215篇 |
妇产科学 | 5103篇 |
基础医学 | 57453篇 |
口腔科学 | 11261篇 |
临床医学 | 66007篇 |
内科学 | 74538篇 |
皮肤病学 | 11394篇 |
神经病学 | 31527篇 |
特种医学 | 16151篇 |
外国民族医学 | 225篇 |
外科学 | 47523篇 |
综合类 | 70280篇 |
现状与发展 | 86篇 |
一般理论 | 64篇 |
预防医学 | 32705篇 |
眼科学 | 12175篇 |
药学 | 46345篇 |
432篇 | |
中国医学 | 25315篇 |
肿瘤学 | 36632篇 |
出版年
2024年 | 1283篇 |
2023年 | 5581篇 |
2022年 | 14566篇 |
2021年 | 19667篇 |
2020年 | 19204篇 |
2019年 | 21901篇 |
2018年 | 21851篇 |
2017年 | 22649篇 |
2016年 | 22388篇 |
2015年 | 28243篇 |
2014年 | 32398篇 |
2013年 | 31057篇 |
2012年 | 32903篇 |
2011年 | 36397篇 |
2010年 | 30360篇 |
2009年 | 22813篇 |
2008年 | 23929篇 |
2007年 | 22611篇 |
2006年 | 21709篇 |
2005年 | 20479篇 |
2004年 | 13989篇 |
2003年 | 13493篇 |
2002年 | 11289篇 |
2001年 | 9516篇 |
2000年 | 9236篇 |
1999年 | 8863篇 |
1998年 | 5478篇 |
1997年 | 5227篇 |
1996年 | 4092篇 |
1995年 | 3809篇 |
1994年 | 3232篇 |
1993年 | 2113篇 |
1992年 | 2607篇 |
1991年 | 2318篇 |
1990年 | 1978篇 |
1989年 | 1718篇 |
1988年 | 1453篇 |
1987年 | 1317篇 |
1986年 | 1116篇 |
1985年 | 824篇 |
1984年 | 479篇 |
1983年 | 387篇 |
1982年 | 212篇 |
1981年 | 237篇 |
1980年 | 166篇 |
1979年 | 256篇 |
1978年 | 148篇 |
1977年 | 125篇 |
1974年 | 119篇 |
1973年 | 114篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Mette Nissen Tiina‐Mari Ikheimo Jukka Huttunen Ville Leinonen Henna‐Kaisa Jyrkknen Mikael von und zu Fraunberg 《Neuromodulation》2021,24(1):102-111
ObjectiveSpinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). We studied the effect of preimplantation opioid use on SCS outcome and the effect of SCS on opioid use during a two-year follow-up period.Materials and methodsThe study cohort included 211 consecutive FBSS patients who underwent an SCS trial from January 1997 to March 2014. Participants were divided into groups, which were as follows: 1) SCS trial only (n = 47), 2) successful SCS (implanted and in use throughout the two-year follow-up period, n = 131), and 3) unsuccessful SCS (implanted but later explanted or revised due to inadequate pain relief, n = 29). Patients who underwent explantation for other reasons (n = 4) were excluded. Opioid purchase data from January 1995 to March 2016 were retrieved from national registries.ResultsHigher preimplantation opioid doses associated with unsuccessful SCS (ROC: AUC = 0.66, p = 0.009), with 35 morphine milligram equivalents (MME)/day as the optimal cutoff value. All opioids were discontinued in 23% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.004). Strong opioids were discontinued in 39% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.04). Mean opioid dose escalated from 18 ± 4 MME/day to 36 ± 6 MME/day with successful SCS and from 22 ± 8 MME/day to 82 ± 21 MME/day with unsuccessful SCS (p < 0.001).ConclusionsHigher preimplantation opioid doses were associated with SCS failure, suggesting the need for opioid tapering before implantation. With continuous SCS therapy and no explantation or revision due to inadequate pain relief, 39% of FBSS patients discontinued strong opioids, and 23% discontinued all opioids. This indicates that SCS should be considered before detrimental dose escalation. 相似文献
2.
Depeng Meng Yichen Meng Bingyang Li Guigang Zeng Bin Zhang Chunlin Hou Haodong Lin Yueping Ouyang 《Journal of orthopaedic science》2021,26(3):409-414
BackgroundComminuted patellar fractures are not rare, and the ideal treatment method remains controversial. The present study was conducted to evaluate effects and compare complications of two different methods used to treat comminuted patellar fractures.MethodsFrom March 2010 to August 2016, 102 cases of 34-C2 or 34-C3 comminuted patellar fractures were treated at our hospital, wherein patients received two different treatments: titanium cable tension band with cerclage method (group A) and intrafragmentary screws with X-shaped plating technique (group B). At follow-ups, articular step-off, range of motion (ROM), Lysholm scores, time of union, and complications were recorded and analyzed. Radiographic and clinical data as well as rate of complications were statistically analyzed.ResultsIn total, 87 patients were included in the final analysis (n = 47 in group A and n = 40 in group B). No significant differences were noted in terms of cost of implant, age, gender, rate of 34-C3 fractures, rate of layered inferior pole fractures, postoperative articular step-off and union time. At 2-year follow-up, average Lysholm scores, ROM and rate of complications were (89.0 ± 4.5), (122°±12°) and (27.7%) in group A and (90.2 ± 3.9), (124°±11°) and (17.5%) in group B, respectively, with no significant differences (p > 0.05). The mean time of surgery in group B was shorter than that in group A with significant difference (p < 0.05).ConclusionsTreatment using the intrafragmentary screws and plate method for amenable comminuted patellar fractures achieved similar complication rate and favorable functional outcomes at the 2-year follow-up, which was comparable to the titanium cable tension band with cerclage method. Thus, the intrafragmentary screws and plate method is effective, safe and convenient for 34-C2/C3 comminuted patellar fractures, especially appropriate for patients with layered fragments. 相似文献
3.
“三全育人”视角下思政教育机制实践与探索——“杏林成长导师”计划的构建 《医学教育管理》2021,7(6):656-660
“三全育人”是高校思政教育工作的关键一环,也是中医药高校推动思政教育的重要内容。以“三全育人”为视角对北京中医药大学思想政治教育举措“杏林成长导师”计划路径、内容深入分析,运用统计分析和文献研究方法,剖析该计划对中医学专业大学生的学业、思想和实践等多个层面的现实成效,从而为“三全育人”理念在中医药院校制度建构中的应用提供新的视角与方法。 相似文献
4.
5.
6.
7.
良性前列腺增生(BPH)是老年男性常见的泌尿系统疾病,其发病与前列腺慢性炎症之间存在显著相关。感染因子、尿液返流、代谢综合征、衰老过程和自身免疫应答在内的几种刺激,通过相应分子途径引起前列腺免疫细胞的组织定位和组成成分发生广泛改变,从而导致免疫系统失调,之后引发的组织损伤和缓慢愈合,导致了BPH发生和进展。本文通过总结良性前列腺增生与前列腺慢性炎症的相关性的临床研究结果,前列腺免疫细胞在病理生理机制层面与前两者之间的内在联系,以及抗炎药物对BPH-LUTS的干预作用,以其为BPH-LUTS的药物研发提供参考。 相似文献
8.
9.