全文获取类型
收费全文 | 22741篇 |
免费 | 1771篇 |
国内免费 | 101篇 |
专业分类
耳鼻咽喉 | 265篇 |
儿科学 | 666篇 |
妇产科学 | 428篇 |
基础医学 | 2825篇 |
口腔科学 | 371篇 |
临床医学 | 2538篇 |
内科学 | 5376篇 |
皮肤病学 | 293篇 |
神经病学 | 1632篇 |
特种医学 | 742篇 |
外科学 | 3351篇 |
综合类 | 302篇 |
一般理论 | 14篇 |
预防医学 | 1792篇 |
眼科学 | 701篇 |
药学 | 1416篇 |
中国医学 | 57篇 |
肿瘤学 | 1844篇 |
出版年
2023年 | 106篇 |
2022年 | 171篇 |
2021年 | 380篇 |
2020年 | 272篇 |
2019年 | 453篇 |
2018年 | 485篇 |
2017年 | 405篇 |
2016年 | 397篇 |
2015年 | 459篇 |
2014年 | 681篇 |
2013年 | 1014篇 |
2012年 | 1374篇 |
2011年 | 1371篇 |
2010年 | 857篇 |
2009年 | 788篇 |
2008年 | 1384篇 |
2007年 | 1439篇 |
2006年 | 1477篇 |
2005年 | 1362篇 |
2004年 | 1326篇 |
2003年 | 1263篇 |
2002年 | 1182篇 |
2001年 | 355篇 |
2000年 | 319篇 |
1999年 | 294篇 |
1998年 | 263篇 |
1997年 | 242篇 |
1996年 | 192篇 |
1995年 | 236篇 |
1994年 | 182篇 |
1993年 | 155篇 |
1992年 | 238篇 |
1991年 | 203篇 |
1990年 | 198篇 |
1989年 | 178篇 |
1988年 | 185篇 |
1987年 | 181篇 |
1986年 | 153篇 |
1985年 | 138篇 |
1984年 | 154篇 |
1983年 | 155篇 |
1982年 | 153篇 |
1981年 | 133篇 |
1980年 | 133篇 |
1979年 | 104篇 |
1978年 | 106篇 |
1977年 | 114篇 |
1976年 | 88篇 |
1975年 | 66篇 |
1974年 | 70篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
Dongbing Lai Emma C. Johnson Sarah Colbert Gayathri Pandey Grace Chan Lance Bauer Meredith W. Francis Victor Hesselbrock Chella Kamarajan John Kramer Weipeng Kuang Sally Kuo Samuel Kuperman Yunlong Liu Vivia McCutcheon Zhiping Pang Martin H. Plawecki Marc Schuckit Jay Tischfield Leah Wetherill Yong Zang Howard J. Edenberg Bernice Porjesz Arpana Agrawal Tatiana Foroud 《Alcoholism, clinical and experimental research》2022,46(3):374-383
2.
Anela Stanic Denis Rybin Francis Cannata Carole Hohl Jennifer Brody Jessie Gaeta 《AIDS care》2021,33(1):1-9
ABSTRACT The lack of stable housing can impair access and continuity of care for patients living with human immunodeficiency virus (HIV). This study investigated the relationship between housing status assessed at multiple time points and several core HIV-related outcomes within the same group of HIV patients experiencing homelessness. Patients with consistently stable housing (CSH) during the year were compared to patients who lacked CSH (non-CSH group). The study outcomes included HIV viral load (VL), CD4 counts, and health care utilization. Multivariable and propensity weighted analyses were used to assess outcomes adjusting for potential group differences. Of 208 patients, 88 (42%) had CSH and 120 (58%) were non-CSH. Patients with CSH had significantly higher proportion of VL suppression and higher mean CD4 counts. The frequency of nurse visits in the CSH group was less than a half of that in the non-CSH group. Patients with CSH were less likely to be admitted to the medical respite facility, and if admitted, their length of stay was about a half of that for the non-CSH group. Our study findings show that patients with CSH had significantly better HIV virologic control and immune status as well as improved health care utilization. 相似文献
3.
Dynamic LVOT Obstruction and Aortic Stenosis in the Same Patient: A Case of Challenging Doppler Hemodynamics
下载免费PDF全文
![点击此处可从《Echocardiography (Mount Kisco, N.Y.)》网站下载免费的PDF全文](/ch/ext_images/free.gif)
Matthew W. Parker M.D. Francis J. Kiernan M.D. 《Echocardiography (Mount Kisco, N.Y.)》2015,32(6):1030-1032
We present a patient with both dynamic left ventricular outflow tract obstruction and valvular aortic stenosis. The aortic valve was calcified, and velocities and gradients measured by continuous‐wave Doppler met standard criteria for severe aortic stenosis. The increased subvalvular velocities invalidated assumptions of the simplified Bernoulli equation; correction using the longer form of the Bernoulli equation suggested a lower but still significant gradient. The complex shape of the subvalvular spectral Doppler envelope indicated supranormal systolic function and dynamic left ventricular outflow obstruction. Left heart catheterization with an end‐hole catheter was required to determine the subvalvular and valvular components of the obstruction. 相似文献
4.
5.
Bernard Natukunda Grace Ndeezi Lay See Er Francis Bajunirwe Gayle Teramura Meghan Delaney 《ISBT科学丛刊》2019,14(4):366-373
6.
7.
8.
9.
Transcapillary fluid balance consequences of missing initial lymphatics studied in a mouse model of primary lymphoedema 总被引:1,自引:0,他引:1
Tine V. Karlsen Marika J. Karkkainen Kari Alitalo Helge Wiig 《The Journal of physiology》2006,574(2):583-596
To investigate the phenotypic consequences of a deranged lymphangiogenesis in relation to tissue fluid accumulation and the possible role of inflammation in the pathogenesis of lymphoedema, we measured determinants of transcapillary fluid filtration and inflammatory mediators in the interstitial fluid in genetically engineered Chy mice, a model for primary congenital lymphoedema (Milroy's disease). Although initial lymphatics were not present in dermis in any of the areas studied (fore paw, hind paw, thigh and back skin) interstitial fluid pressure ( P if ), measured with micropipettes, and tissue fluid volumes were significantly increased only in the areas with visible swelling – the fore and hind paw, whereas interstitial colloid osmotic pressure (COPif ) was increased in all the skin areas examined. A volume load of 15% of body weight resulted in a more pronounced increase in P if as well as a four-fold increase in interstitial fluid volume in Chy relative to wild-type (wt) mice, showing the quantitative importance of lymphatics for fluid homeostasis during acute perturbations. A similar level of proinflammatory markers in interstitial fluid in early established lymphoedema (3–4 months) in Chy and wt suggests that inflammation does not have a major pathogenetic role for the development of lymphoedema, whereas a reduced level of the immunomodulatory cytokine interleukin (IL)-4 may result in a reduced immunological defence ability and thus lead to the increase in inflammatory cytokines IL-2 and IL-6 observed at a later stage (11–13 months). Our data suggest that primary lymphoedema results in a high interstitial fluid protein concentration that does not induce an interstitial inflammatory reaction per se , and furthermore shows the paramount importance of the initial lymphatics in tissue fluid homeostasis, especially during perturbations of transcapillary fluid balance. 相似文献
10.
Kari Hemminki Xinjun Li 《Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine》2003,45(4):456-461
Epidemiologic data on pleural mesothelioma are scarce on regional and occupational time trends, which would monitor the effects of changes in exposure to asbestos. We aim to characterize time trends, regional, socioeconomic, and occupational risk factors for pleural mesothelioma in Sweden in the years from 1961 to 1998. The Swedish Family-Cancer Database was used to identify patients with pleural mesothelioma. Age-standardized incidence rates and standardized incidence ratio (SIR) were calculated for the population in the Database. A total of 1298 male and 233 female pleural mesotheliomas were retrieved. Age-standardized incidence of the disease was highest, and the trend increased in residents of large industrial and shipbuilding cities. In the last follow-up period, the male rate exceeded the female rate about 10-fold. Among male socioeconomic groups, manual workers showed the highest and ever-increasing SIR. No female socioeconomic group was at risk. For men, plumbers and seamen had the highest risk of 4.56 and 2.83, respectively, but the risks appeared to be decreasing for plumbers, whereas no clear trend was noted for seamen, probably because of indirect expose in ships. Farmers showed an SIR of 0.28, indicating that the population at large was at four times higher risk than farmers. The SIRs of many academic/college-educated groups were two to six times higher than those of farmers, suggesting indirect exposure to asbestos in these groups. 相似文献