全文获取类型
收费全文 | 1168篇 |
免费 | 78篇 |
专业分类
儿科学 | 13篇 |
妇产科学 | 75篇 |
基础医学 | 209篇 |
口腔科学 | 1篇 |
临床医学 | 66篇 |
内科学 | 207篇 |
皮肤病学 | 189篇 |
神经病学 | 59篇 |
特种医学 | 53篇 |
外科学 | 95篇 |
综合类 | 4篇 |
一般理论 | 3篇 |
预防医学 | 80篇 |
眼科学 | 11篇 |
药学 | 35篇 |
肿瘤学 | 146篇 |
出版年
2021年 | 9篇 |
2020年 | 6篇 |
2019年 | 6篇 |
2018年 | 16篇 |
2017年 | 11篇 |
2016年 | 18篇 |
2015年 | 9篇 |
2014年 | 22篇 |
2013年 | 48篇 |
2012年 | 41篇 |
2011年 | 44篇 |
2010年 | 29篇 |
2009年 | 33篇 |
2008年 | 49篇 |
2007年 | 63篇 |
2006年 | 57篇 |
2005年 | 38篇 |
2004年 | 39篇 |
2003年 | 59篇 |
2002年 | 54篇 |
2001年 | 54篇 |
2000年 | 42篇 |
1999年 | 34篇 |
1998年 | 15篇 |
1997年 | 21篇 |
1996年 | 12篇 |
1995年 | 12篇 |
1994年 | 8篇 |
1993年 | 14篇 |
1992年 | 22篇 |
1991年 | 26篇 |
1990年 | 24篇 |
1989年 | 29篇 |
1988年 | 27篇 |
1987年 | 21篇 |
1986年 | 24篇 |
1985年 | 26篇 |
1984年 | 13篇 |
1983年 | 22篇 |
1982年 | 21篇 |
1981年 | 12篇 |
1980年 | 7篇 |
1979年 | 10篇 |
1978年 | 8篇 |
1977年 | 6篇 |
1974年 | 13篇 |
1973年 | 5篇 |
1972年 | 9篇 |
1971年 | 6篇 |
1970年 | 6篇 |
排序方式: 共有1246条查询结果,搜索用时 46 毫秒
1.
Prof. Dr. Alexander Kapp Prof. Dr. Bettina Wedi 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》2006,57(10):854-854
Ohne Zusammenfassung 相似文献
2.
3.
Dr. K. Breuer A. Kapp 《Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete》2006,57(7):592-602
Atopic dermatitis is a chronic inflammatory skin disease which often persists until adulthood. In severe cases, eczematous lesions and pruritus are resistant to therapy and result in depression, impairment of professional activities and social withdrawal. The goal of inpatient rehabilitation measures is to keep the patient involved and active in professional and social activities. Rehabilitative measures include diagnostics and medical therapy according to current guidelines, instruction in basic medical information, psychological intervention (relaxation techniques, improvement of self-confidence), dietetic measures, exercise, and social advice. Patients with atopic dermatitis often have work-related problems which should be identified as early as possible during rehabilitation. 相似文献
4.
Persistent and/or late complications were analysed in 64 patients (183 fields) that were treated with combined hyperthermia and radiation therapy for advanced, recurrent or metastatic cancer. The incidence and type of complications were evaluated over a minimum follow-up period of 2 years from the onset of treatment (mean 38.7 months; range 24-82.5 months). The primary malignancies included: breast (39), melanomas (6), adenoid cystic carcinomas of salivary glands (4), prostate (4), soft tissue sarcomas (3), squamous cell carcinoma of head and neck (3), lymphomas (3), transitional cell carcinoma of bladder (1) and basal cell carcinoma of the skin (1). The persistent complications noted included induration and fibrosis (39 hyperthermia fields, 22 patients), ulceration at the site of prior tumour (three patients, three fields), and ulceration in normal tissue (one patient, one field). Brachial plexopathy developed in one patient treated for recurrent breast cancer, but she had active disease at that time. A squamous cell carcinoma of the skin developed within the treatment field in a breast cancer patient. Radionecrosis of the mandible was seen in one patient treated for a floor of the mouth cancer, and osteomyelitis with septic arthritis developed in one patient treated for a soft tissue sarcoma of the thigh. Univariate logistic regression analyses of pretreatment and radiation-hyperthermia treatment parameters revealed that maximal tumour temperature had a borderline significant correlation with the development of complications (p = 0.07). Multivariate analyses of the pretreatment and treatment parameters revealed the best-two-covariate model to predict complications included mean maximal tumour temperature and tumour type (macroscopic tumours had greater incidence of complications than for microscopic residual disease). The rate and type of persistent and/or late complications seen following combined radiation and hyperthermia did not appear to dramatically differ from those that would be anticipated from irradiation alone in this patient population, with the exception of an increased incidence of areas of induration and tumour necrosis. 相似文献
5.
During the past 10 years, numerous phase I-II studies were conducted and provided clinical experience with combined radiation therapy and hyperthermia treatments. Among the rare complications reported in these combined radiation therapy-hyperthermia trials were myonecrosis and peripheral neuropathy which were felt, mainly on a clinical basis, to be caused by local heat damage. Recently, such complications were noted in two patients with recurrent prostatic cancer treated in our department with radiation therapy combined with deep regional hyperthermia delivered by the Sigma-60 applicator of the BSD 2000 hyperthermia system (Salt Lake City, UT, USA). Analysis of the results of three-dimensional modelling of the SAR (specific absorption rate, W/kg) pattern in these patients indicated high SAR at the sites of the complications. Pretreatment three-dimensional modelling or other methods of predicting potential areas of high power deposition may have a role for future hyperthermia treatment planning aiding in the prevention of possible local heat damage and providing improved delivery of heat to the target volume. 相似文献
6.
M B Kapp 《Social work in health care》1988,13(4):1-13
This essay examines the interplay between the ethical principles of autonomy and beneficence in the context of deciding whether to intervene in the life of an at-risk older adult by providing health and human services over the older person's objection. The need to distinguish between the rights and welfare of the older client, on one hand, and the interests and drives of the professional caregiver, on the other hand, is emphasized. 相似文献
7.
M B Kapp 《Clinics in Geriatric Medicine》1988,4(3):667-679
The law is concerned with a panoply of issues affecting the care and lives of nursing home residents. This article has outlined one area, that of decision making, which in many respects is the embodiment of and key to all other fundamental resident rights. The doctrine of informed consent applies with full force in the nursing home, both for mentally competent residents and for cognitively impaired residents for whom decision making rights must be exercised through a proxy. Long-term care institutions and professionals are obligated to insure that decisions made by or for residents are made voluntarily, competently, and knowingly. 相似文献
8.
C von Kalle J Wolf A Becker A Sckaer M Munck A Engert U Kapp C Fonatsch D Komitowski W Feaux de Lacroix 《International journal of cancer. Journal international du cancer》1992,52(6):887-891
No animal model exists for the in vivo growth of Hodgkin's-lymphoma-derived cells. Neither unmanipulated Hodgkin's-disease(HD)-derived cell lines nor primary biopsy tissue could be grown in nude mice. Since the severe combined immunodeficient (SCID) mouse has been reported to be a better recipient for transplanted human lymphatic tissue than the nude mouse, we tested whether SCID mice provide suitable conditions for the in vivo growth of HD cell lines. Tumorigenicity of HD cells was tested in untreated and pre-treated SCID mice and in another combined immunodeficient mouse strain, beige/nude/X-linked immunodeficient (BNX) mouse. SCID mice supported in vivo growth of the 6 HD cell lines tested (L428, L540, L591, DEV, HD-LM2, KM-H2). Only one of the 6 lines (DEV) was tumorigenic in BNX mice. No HD cell line proliferated in T-cell-deficient nude mice. Thus, in vivo growth of HD cell lines appeared to be related to the degree of host immunodeficiency. Additional growth supportive treatments such as fibrosarcoma co-transplantation, intraperitoneal mineral oil injection or immunosuppressive pre-treatment (anti-asialo-GMI-antibody injection) permitted growth of 3 additional HD cell lines in BNX mice. The immunophenotype and karyotype of explanted graft cells were identical to the original cell lines. Our experiments describe an effective and reproducible xenograft model for growth of Hodgkin's-disease-derived cell lines. This may be of value for elucidating the growth characteristics of Hodgkin's-lymphoma-derived cells as well as for testing new therapeutic regimens. 相似文献
9.
10.