全文获取类型
收费全文 | 52331篇 |
免费 | 3642篇 |
国内免费 | 625篇 |
专业分类
耳鼻咽喉 | 801篇 |
儿科学 | 2033篇 |
妇产科学 | 1127篇 |
基础医学 | 6601篇 |
口腔科学 | 2074篇 |
临床医学 | 4959篇 |
内科学 | 10278篇 |
皮肤病学 | 1460篇 |
神经病学 | 4087篇 |
特种医学 | 1816篇 |
外国民族医学 | 2篇 |
外科学 | 7624篇 |
综合类 | 1523篇 |
现状与发展 | 2篇 |
一般理论 | 17篇 |
预防医学 | 3403篇 |
眼科学 | 1278篇 |
药学 | 3898篇 |
2篇 | |
中国医学 | 671篇 |
肿瘤学 | 2942篇 |
出版年
2024年 | 58篇 |
2023年 | 472篇 |
2022年 | 547篇 |
2021年 | 1252篇 |
2020年 | 850篇 |
2019年 | 1196篇 |
2018年 | 1838篇 |
2017年 | 1370篇 |
2016年 | 1492篇 |
2015年 | 1521篇 |
2014年 | 1843篇 |
2013年 | 2521篇 |
2012年 | 3969篇 |
2011年 | 4571篇 |
2010年 | 2226篇 |
2009年 | 1505篇 |
2008年 | 3671篇 |
2007年 | 3819篇 |
2006年 | 3616篇 |
2005年 | 3496篇 |
2004年 | 3289篇 |
2003年 | 3114篇 |
2002年 | 2859篇 |
2001年 | 1074篇 |
2000年 | 1160篇 |
1999年 | 742篇 |
1998年 | 332篇 |
1997年 | 279篇 |
1996年 | 230篇 |
1995年 | 183篇 |
1994年 | 152篇 |
1993年 | 146篇 |
1992年 | 150篇 |
1991年 | 131篇 |
1990年 | 104篇 |
1989年 | 95篇 |
1988年 | 74篇 |
1987年 | 52篇 |
1986年 | 54篇 |
1985年 | 58篇 |
1984年 | 51篇 |
1983年 | 41篇 |
1982年 | 52篇 |
1981年 | 49篇 |
1980年 | 37篇 |
1979年 | 37篇 |
1978年 | 27篇 |
1977年 | 40篇 |
1976年 | 19篇 |
1973年 | 20篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
2.
Esin Benli Küçük Ercan Kaydok Kürsad Ramazan Zor Gamze Yıldırım Biçer 《Topics in stroke rehabilitation》2020,27(8):630-635
ABSTRACT Objective: Dry eye is reported to be associated with several neurological diseases. The aim of this study is to evaluate the patients with hemiplegia after stroke for dry eye and compare their results with a control group. Materials and methods: Forty-five patients with hemiplegia and 45 individuals as the control group were included in the study. Tear function tests (Schirmer and tear breakup time) and a dry eye questionnaire for dry eye symptoms (ocular surface disease index) were performed and the results of the two groups were compared. Results: Schirmer test results were significantly lower in the post-stroke hemiplegia group compared to the control group (11.3 ± 8.2 mm and 20.6 ± 11.6 mm, respectively, p < .001). Tear breakup time results were significantly lower in the post-stroke hemiplegia group compared to the control group (7.9 ± 3.1 s and 12.1 ± 4.3 s, respectively, p < .001). Ocular surface disease index scores were not significantly different between hemiplegia and control groups (21.6 ± 20.0 and 19.8 ± 13.9, respectively, p = .635). Schirmer scores lower than 10 mm (60% and 30%, p < .001) and tear breakup time results lower than 10 s (65.6% and 28.9%, p < .001) were also higher in the hemiplegia group compared to control group. Conclusion: We found lower Schirmer test and tear breakup time results and similar OSDI scores in hemiplegia patients compared to controls. Hemiplegia patients may have dry eye without typical symptoms. This should be taken into consideration in the follow-up and rehabilitation of post-stroke hemiplegia patients. 相似文献
3.
4.
5.
目的探讨腹腔镜经腹腹膜前疝修补术(TAPP)放置腹膜前引流对术后血肿及血清肿的影响。
方法选取2016年6月至2018年5月,江苏省苏州市中西医结合医院收治的单侧腹股沟疝患者90例,随机分为试验组和对照组,2组患者均行TAPP手术。试验组放置腹膜前引流管,对照组不放置引流管。收集2组患者的一般资料、手术相关资料及随访资料进行统计学分析,对比2组患者术后血肿及血清肿发生率差异。
结果全部患者均完成手术及随访。2组患者的一般资料、疝位置、疝分型、手术时间、住院花费、术后住院时间差异无统计学意义(P>0.05)。2组患者的术后发热发生率、急性疼痛发生率差异无统计学意义(P>0.05)。试验组术后血肿发生率明显低于对照组(P<0.05),试验组患者术后1和3个月血清肿发生率明显低于对照组,差异有统计学意义(P<0.05)。2组患者1年随访均观察到1例复发的病例,差异无统计学意义(P>0.05);随访期内2组患者均未出现感染的病例。
结论TAPP中,放置腹膜前引流管能够有效降低患者术后血肿和血清肿的发生率,同时并不增加感染和复发风险。 相似文献
6.
7.
8.
9.
Claire Letournel François Babinet Bénédicte Allard Vincent Montecot 《Néphrologie & thérapeutique》2019,15(1):51-58
Objective
The “Centre Hospitalier Francois Dunan” is located on an isolated island and ensures patients care in hemodialysis thanks to telemedicine support. Many research studies have demonstrated the importance of hemodialysis fluids composition to reduce morbidity in patients on chronic hemodialysis. The aim of this study was to identify the risks inherent in the production of dialysis fluids in a particular context, in order to set up an improvement action plan to improve risk control on the production of dialysis fluids.Methods
The risk analysis was conducted with the FMECA methodology (Failure Mode, Effects and Criticality Analysis) by a multi professional work group. Three types of risk have been reviewed: technical risks that may impact the production of hemodialysis fluids, health risks linked with chemical composition and health risks due to microbiological contamination of hemodialysis fluids.Results
The work group, in close cooperation with the expert staff of the dialysis center providing telemedicine assistance, has developed an action plan in order to improve the control of the main risks brought to light by the risk analysis.Conclusion
The exhaustive analysis of the risks and their prioritisation have permitted to establish a relevant action plan in this improving quality of dialysis fluids approach. The risk control of dialysis fluids is necessary for the security of dialysis sessions for patients, even more when these sessions are realized by telemedicine in Saint-Pierre-et-Miquelon. 相似文献10.
Anatoly E Martynyuk Ling-Sha Ju Timothy E Morey Jia-Qiang Zhang 《World Journal of Psychiatry》2020,10(5):81-94
The progress of modern medicine would be impossible without the use of general anesthetics (GAs). Despite advancements in refining anesthesia approaches, the effects of GAs are not fully reversible upon GA withdrawal. Neurocognitive deficiencies attributed to GA exposure may persist in neonates or endure for weeks to years in the elderly. Human studies on the mechanisms of the long-term adverse effects of GAs are needed to improve the safety of general anesthesia but they are hampered not only by ethical limitations specific to human research, but also by a lack of specific biological markers that can be used in human studies to safely and objectively study such effects. The latter can primarily be attributed to an insufficient understanding of the full range of the biological effects induced by GAs and the molecular mechanisms mediating such effects even in rodents, which are far more extensively studied than any other species. Our most recent experimental findings in rodents suggest that GAs may adversely affect many more people than is currently anticipated. Specifically, we have shown that anesthesia with the commonly used GA sevoflurane induces in exposed animals not only neuroendocrine abnormalities (somatic effects), but also epigenetic reprogramming of germ cells (germ cell effects). The latter may pass the neurobehavioral effects of parental sevoflurane exposure to the offspring, who may be affected even at levels of anesthesia that are not harmful to the exposed parents. The large number of patients who require general anesthesia, the even larger number of their future unexposed offspring whose health may be affected, and a growing number of neurodevelopmental disorders of unknown etiology underscore the translational importance of investigating the intergenerational effects of GAs. In this mini review, we discuss emerging experimental findings on neuroendocrine, epigenetic, and intergenerational effects of GAs. 相似文献