全文获取类型
收费全文 | 44549篇 |
免费 | 2834篇 |
国内免费 | 506篇 |
专业分类
耳鼻咽喉 | 529篇 |
儿科学 | 1000篇 |
妇产科学 | 845篇 |
基础医学 | 5602篇 |
口腔科学 | 1515篇 |
临床医学 | 3635篇 |
内科学 | 10501篇 |
皮肤病学 | 839篇 |
神经病学 | 3535篇 |
特种医学 | 1088篇 |
外国民族医学 | 2篇 |
外科学 | 6888篇 |
综合类 | 1235篇 |
一般理论 | 14篇 |
预防医学 | 2957篇 |
眼科学 | 970篇 |
药学 | 2891篇 |
7篇 | |
中国医学 | 398篇 |
肿瘤学 | 3438篇 |
出版年
2023年 | 283篇 |
2022年 | 529篇 |
2021年 | 1352篇 |
2020年 | 799篇 |
2019年 | 1144篇 |
2018年 | 1383篇 |
2017年 | 919篇 |
2016年 | 1056篇 |
2015年 | 1334篇 |
2014年 | 1733篇 |
2013年 | 2104篇 |
2012年 | 3294篇 |
2011年 | 3484篇 |
2010年 | 1969篇 |
2009年 | 1809篇 |
2008年 | 2758篇 |
2007年 | 2904篇 |
2006年 | 2673篇 |
2005年 | 2562篇 |
2004年 | 2343篇 |
2003年 | 2174篇 |
2002年 | 2144篇 |
2001年 | 811篇 |
2000年 | 619篇 |
1999年 | 550篇 |
1998年 | 414篇 |
1997年 | 324篇 |
1996年 | 293篇 |
1995年 | 298篇 |
1994年 | 279篇 |
1993年 | 247篇 |
1992年 | 304篇 |
1991年 | 273篇 |
1990年 | 229篇 |
1989年 | 198篇 |
1988年 | 192篇 |
1987年 | 175篇 |
1986年 | 182篇 |
1985年 | 192篇 |
1984年 | 167篇 |
1983年 | 118篇 |
1982年 | 130篇 |
1981年 | 107篇 |
1980年 | 87篇 |
1979年 | 103篇 |
1978年 | 89篇 |
1977年 | 72篇 |
1975年 | 82篇 |
1974年 | 72篇 |
1973年 | 71篇 |
排序方式: 共有10000条查询结果,搜索用时 92 毫秒
1.
Exhaled nitric oxide in children with allergic rhinitis: A potential biomarker of asthma development
下载免费PDF全文
![点击此处可从《Pediatric allergy and immunology》网站下载免费的PDF全文](/ch/ext_images/free.gif)
2.
3.
4.
Lara Silveira Abdo Aguiar Rita de Cssia Rossini Lismary Aparecida de Forville Mesquita Gerson Dellatorre 《Journal of Cosmetic Dermatology》2019,18(6):1733-1736
Depigmented lesions may occur as postinflammatory sequelae of subacute cutaneous lupus erythematosus (SCLE), leading to great psychosocial impact. A 53‐year‐old male patient presented with post‐SCLE depigmented facial lesions after five years of disease stability. We proposed surgical treatment with melanocyte‐keratinocyte transplantation procedure (MKTP), and after five months the patient achieved 90% repigmentation, without Koebner phenomenon (KP). In theory, KP is a possible complication of MKTP procedure since the preparation of the receptor area involves the use of dermabrasion. In an attempt to avoid it, we suggest to maintain the treatment of the underlying disease and wait for a minimum period of disease stability before the procedure. 相似文献
5.
Jose M. Morales Jose Angel Martinez-Flores Manuel Serrano Maria José Castro Francisco Javier Alfaro Florencio García Miguel Angel Martínez Amado Andrés Esther González Manuel Praga Estela Paz-Artal Antonio Serrano 《Journal of the American Society of Nephrology : JASN》2015,26(3):735-745
In the current immunosuppressive therapy era, vessel thrombosis is the most common cause of early graft loss after renal transplantation. The prevalence of IgA anti–β2-glycoprotein I antibodies (IgA-aB2GPI-ab) in patients on dialysis is elevated (>30%), and these antibodies correlate with mortality and cardiovascular morbidity. To evaluate the effect of IgA-aB2GPI-ab in patients with transplants, we followed all patients transplanted from 2000 to 2002 in the Hospital 12 de Octubre prospectively for 10 years. Presence of IgA-aB2GPI-ab in pretransplant serum was examined retrospectively. Of 269 patients, 89 patients were positive for IgA-aB2GPI-ab (33%; group 1), and the remaining patients were negative (67%; group 2). Graft loss at 6 months post-transplant was significantly higher in group 1 (10 of 89 versus 3 of 180 patients in group 2; P=0.002). The most frequent cause of graft loss was thrombosis of the vessels, which was observed only in group 1 (8 of 10 versus 0 of 3 patients in group 2; P=0.04). Multivariate analysis showed that the presence of IgA-aB2GPI-ab was an independent risk factor for early graft loss (P=0.04) and delayed graft function (P=0.04). There were no significant differences regarding patient survival between the two groups. Graft survival was similar in both groups after 6 months. In conclusion, patients with pretransplant IgA-aB2GPI-ab have a high risk of early graft loss caused by thrombosis and a high risk of delayed graft function. Therefore, pretransplant IgA-aB2GPI-ab may have a detrimental effect on early clinical outcomes after renal transplantation. 相似文献
6.
7.
利用空间频域成像技术搭建的成像系统检测多种皮肤病组织的光学参数和生理参数信息,并对比分析讨论不同类型的皮肤病与光学参数、生理参数之间的关系。实验结果表明,病变皮肤组织与正常皮肤组织之间在光学参数、生理参数上存在较大差异,这将为临床医生对皮肤病诊治提供一种新颖、可靠、科学的评估方法。 相似文献
8.
9.
Peng‐fei Lei Shi‐long Su Ling‐yu Kong Cheng‐gong Wang Da Zhong Yi‐he Hu 《Orthopaedic Surgery》2019,11(5):914-920
Three‐dimensional (3D) printing technology, virtual reality, and augmented reality technology have been used to help surgeons to complete complex total hip arthroplasty, while their respective shortcomings limit their further application. With the development of technology, mixed reality (MR) technology has been applied to improve the success rate of complicated hip arthroplasty because of its unique advantages. We presented a case of a 59‐year‐old man with an intertrochanteric fracture in the left femur, who had received a prior left hip fusion. After admission to our hospital, a left total hip arthroplasty was performed on the patient using a combination of MR technology and 3D printing technology. Before surgery, 3D reconstruction of a certain bony landmark exposed in the surgical area was first performed. Then a veneer part was designed according to the bony landmark and connected to a reference registration landmark outside the body through a connecting rod. After that, the series of parts were made into a holistic reference registration instrument using 3D printing technology, and the patient's data for bone and surrounding tissue, along with digital 3D information of the reference registration instrument, were imported into the head‐mounted display (HMD). During the operation, the disinfected reference registration instrument was installed on the selected bony landmark, and then the automatic real‐time registration was realized by HMD through recognizing the registration landmark on the reference registration instrument, whereby the patient's virtual bone and other anatomical structures were quickly and accurately superimposed on the real body of the patient. To the best of our knowledge, this is the first report to use MR combined with 3D printing technology in total hip arthroplasty. 相似文献
10.
Dana Franzen-Klein Mark Jankowski Charlotte L. Roy Hoa Nguyen-Phuc Da Chen Lorin Neuman-Lee 《Journal of toxicology and environmental health. Part A》2020,83(2):45-65
ABSTRACTDomestic chickens (Gallus gallus domesticus) were exposed to imidacloprid by gavage once daily for 7 consecutive days at 0, 0.03, 0.34, 3.42, 10.25, and 15.5 mg/kg/day (n = 20 per group; 5 6-week-old males, 5 6-week-old females, 5 9-week-old males, and 5 9-week-old females). The severity and duration of neurobehavioral abnormalities were recorded. Components of the innate and adaptive immune system were assessed with 7 standard functional assays. Temporary neurobehavioral abnormalities were observed in a dose-dependent manner, including muscle tremors, ataxia, and depressed mentation. Based upon mean clinical severity scores, the no observed adverse effect level (NOAEL) was 3.42 mg/kg/day, and the lowest observed adverse effect level (LOAEL) was 10.25 mg/kg/day. The effective dose value for the presence of any neurobehavioral abnormalities in 50% of the test group (ED50) was 4.62 ± 0.98 mg/kg/day. The ED50 for an adjusted score that included both severity and duration of neurobehavioral abnormalities was 11.24 ± 9.33 mg/kg/day. These ED50 values are equivalent to a 1 kg bird ingesting 29 or 70 imidacloprid treated soybean seeds respectively. Immunotoxicity was not documented, possible causes include the assays were insensitive, relevant immune functions were not examined, or imidacloprid is not immunotoxic at this dosing schedule in this species. Neurobehavioral abnormalities were a more sensitive indicator of the sublethal effects of imidacloprid than immunotoxicity. 相似文献