全文获取类型
收费全文 | 8639篇 |
免费 | 653篇 |
国内免费 | 21篇 |
专业分类
耳鼻咽喉 | 65篇 |
儿科学 | 293篇 |
妇产科学 | 274篇 |
基础医学 | 1033篇 |
口腔科学 | 127篇 |
临床医学 | 1149篇 |
内科学 | 1485篇 |
皮肤病学 | 128篇 |
神经病学 | 771篇 |
特种医学 | 193篇 |
外科学 | 836篇 |
综合类 | 69篇 |
一般理论 | 16篇 |
预防医学 | 1201篇 |
眼科学 | 131篇 |
药学 | 623篇 |
中国医学 | 13篇 |
肿瘤学 | 906篇 |
出版年
2024年 | 23篇 |
2023年 | 113篇 |
2022年 | 125篇 |
2021年 | 230篇 |
2020年 | 202篇 |
2019年 | 248篇 |
2018年 | 264篇 |
2017年 | 219篇 |
2016年 | 269篇 |
2015年 | 261篇 |
2014年 | 321篇 |
2013年 | 481篇 |
2012年 | 687篇 |
2011年 | 766篇 |
2010年 | 375篇 |
2009年 | 311篇 |
2008年 | 589篇 |
2007年 | 581篇 |
2006年 | 573篇 |
2005年 | 525篇 |
2004年 | 416篇 |
2003年 | 431篇 |
2002年 | 381篇 |
2001年 | 88篇 |
2000年 | 57篇 |
1999年 | 78篇 |
1998年 | 65篇 |
1997年 | 50篇 |
1996年 | 49篇 |
1995年 | 40篇 |
1994年 | 42篇 |
1993年 | 33篇 |
1992年 | 40篇 |
1991年 | 20篇 |
1990年 | 32篇 |
1989年 | 24篇 |
1988年 | 20篇 |
1987年 | 17篇 |
1986年 | 26篇 |
1984年 | 16篇 |
1983年 | 20篇 |
1982年 | 15篇 |
1981年 | 16篇 |
1980年 | 10篇 |
1979年 | 21篇 |
1978年 | 10篇 |
1977年 | 11篇 |
1975年 | 20篇 |
1974年 | 17篇 |
1973年 | 10篇 |
排序方式: 共有9313条查询结果,搜索用时 15 毫秒
1.
Charlotte J. Harden Bernard M. Corfe J. Craig Richardson Peter W. Dettmar Jenny R. Paxman 《Nutrition Research》2009
This cross-sectional analysis evaluated the effect of age and body mass index (BMI) on Three-Factor Eating Questionnaire scores in males. Subjects (n = 60) were recruited according to BMI status. Each completed the 51-item Three-Factor Eating Questionnaire. The group was split at the median age to produce a “younger” and “older” group for statistical analysis. A 2-way between-groups analysis of variance revealed a significant main effect of BMI on disinhibition (P = .003) and hunger (P = .041) with higher levels found in overweight males compared to healthy-weight counterparts. A significant main effect of age on hunger (P = .046) demonstrated older males were less susceptible to hunger than younger males. These insights provide a better understanding of eating behavior across the male life cycle and may assist health professionals to better guide men in weight management in the light of rising overweight/obesity. 相似文献
2.
Jenny Andersson Barbro Linderholm Jonas Bergh Goran Elmberger 《Applied immunohistochemistry & molecular morphology》2004,12(1):14-20
We have studied the intratumor HER-2/neu heterogeneity in 78 consecutive and population-based primary invasive breast carcinomas. Within the invasive component, heterogeneity was detected in only 1 of 78 tumors. In 48 tumors (62%), we found both in situ and invasive components in analyzed tissue sections. Twelve of these 48 tumors had a difference of at least 2 arbitrary units in the in situ compared with the invasive part of the tumor with regard to the HER-2/neu status analyzed by HercepTest (immunohistochemistry). Eight of these 12 tumors were reanalyzed with fluorescent in situ hybridization and immunohistochemistry with and without a new Automated Cellular Imaging System. In this limited material, immunohistochemistry in combination with the Automated Cellular Imaging System seemed to have a better correlation with fluorescent in situ hybridization than immunostaining analyzed manually. In conclusion, HER-2/neu expression is not seldom heterogeneous in invasive compared with in situ components within a tumor. This finding should be considered in the choice of evaluation method. To avoid heterogeneity as a confounding factor in HER-2/neu analyses, detection methods such as immunohistochemistry and fluorescent in situ hybridization, which can provide evaluation in a preserved tissue architecture, should be used. Perhaps the intratumor HER-2/neu heterogeneity can explain some of the unexpected failures of trastuzumab therapy. 相似文献
3.
This report looks at outpatient treatment of nasopharyngeal inlet stenosis, a more commonly seen postoperative complication of uvulopalatopharyngoplasty (UPPP). It does not study the effectiveness of the UPPP for treatment of obstructive sleep apnea syndrome (OSAS). The authors evaluated six patients who had a UPPP for OSAS, all of whom developed stenosis in the nasopharyngeal inlet ranging from 14 mm to complete closure. Two patients had failed rotation flap repairs. The carbon dioxide laser was used to treat these patients in the office under a local anesthesia in a staged manner. We now have patients from 3 months to 12 months follow-up who have had stenosis treated successfully. We believe that the postoperative complication of nasopharyngeal inlet stenosis after UPPP can be treated in a safe and cost-effective manner in the office setting. 相似文献
4.
The involvement of children in research studies is historically fraught with difficulties. Experiments on children without their consent or knowledge have been carried out in the past and thus the need for stringent ethical control is undoubtedly necessary. However this paper argues that the need to protect children from unethical research has somehow become entwined in the web of secrecy that surrounds the very nature of child abuse. In the name of 'protection' are children in danger of not having their voice heard?
In the foreword to 'Listening to Children' (Alderson, 1995) Roger Singleton writes, 'much research is carried out on and about children, but seldom with children. Children themselves are often strangely silent'. This paper draws on recent literature on the institutional abuse of young people in residential care and the lack of voice that those abused in residential care have traditionally had, suggesting that their silence is not 'strange' but perhaps contrived.
This paper does not repeat the work of Alderson (1995) and make suggestions as to how research with children may best be carried out, but seeks to address the issues in relation to research with children who are in institutions. 相似文献
In the foreword to 'Listening to Children' (Alderson, 1995) Roger Singleton writes, 'much research is carried out on and about children, but seldom with children. Children themselves are often strangely silent'. This paper draws on recent literature on the institutional abuse of young people in residential care and the lack of voice that those abused in residential care have traditionally had, suggesting that their silence is not 'strange' but perhaps contrived.
This paper does not repeat the work of Alderson (1995) and make suggestions as to how research with children may best be carried out, but seeks to address the issues in relation to research with children who are in institutions. 相似文献
5.
Gregor McWalter MA MSc Hugh Toner MA DipCouns MSc CPsychol Alison Corser BSc MPhil CPsychol Jenny Eastwood MBChB DipSocMed FRCPsych Mary Marshall MA DSA DASS Tony Turvey BSc MAppSci CPsychol 《Health & social care in the community》1994,2(4):213-219
The concept of need and the practice of needs assessment are both subject to a wide range of interpretations, to the likely detriment of individual assessments and to multidisciplinary working. Clear definition is important for individual assessment, for the development of multidisciplinary tools and in gathering planning information. The concept of need is clarified, firstly by distinguishing between need and the difficulties that engender it, and secondly through a taxonomy of need. These assist clear definitions of both need and needs assessment when linked with a consideration of the current help a person receives and a specification of the type of help required by a person to meet their needs. Such definitions have implications for the role of needs assessment in individual assessment, service evaluation, service management and planning and in the development of multidisciplinary needs assessment tools. 相似文献
6.
Guoping Lian Mark E Malone Jenny E Homan Ian T Norton 《Journal of controlled release》2004,98(1):139-155
This paper presents a mathematical model of in-mouth volatile release from gelled emulsion particles dispersed in a continuous aqueous phase. Data based on APCI MS-Breath analysis is presented to demonstrate the effect of particle size, oil content and oil-water partition coefficients. It is shown that in-mouth release of aroma from the dispersion of gelled emulsion particles follows a two-component kinetic equation with fast and slow components. Both the fast and slow rate constants depend on the particle size, oil content and oil water partition coefficient of the aroma. The relative amount of aroma contributing to the fast and slow components also depends on the size of the particles. In order to understand this unexpected behaviour, an analytical model was developed that considers the interplay between the mass transfer of flavour across the interface of the particles and that across the air-liquid interface. Analytical expressions for the two rate constants and the relative ratio of aroma contributing to the fast component have been derived. From this model, three regimes of in-mouth release of aroma from the dispersion of gelled emulsion particles were identified including, the emulsion regime, the transition regime and the gel particle regime. In the emulsion regime, changes in the size of gelled emulsion particles had negligible impact on the overall release. In the transition regime, the release was controlled by the interaction of flavour transfer from the particles with that across the air-water interface. In the gel particle regime, aroma release at long times was governed by the particles and that at short times was governed by the air-water interface, and the two processes were fully decoupled. A simple relationship was derived for the critical size above which the release of aroma from the dispersion of gelled emulsion particles is affected by the size of the particles. 相似文献
7.
This paper reports the prevalence of chronic esophagitis and nutritional status among 538 young persons aged 15 to 26 years from the high risk area for esophageal cancer. Of these subjects, 166 were from households with history of esophageal cancer and 372 were from households without history of esophageal cancer. The Incidences of chronic esophagltis among male and female adolescents were 37. 6% and 36% respectively, which was significantly higher than those in the low risk area (17%). The frequency of chronic esophagltis in the adolescents in the households with history of esophageal cancer was aiso higher than in those In the households without history of esophageal cancer. The deficiencies of vitamins, especially of riboflavin and ascorbate, are prevalent and severe among these adolescents. Ascorbate deficiency Is correlated with the severity of the chronic esophagltis. These results indicate that chronic esophagltis may be involved in the natural history of esophageal carclnogenesis. Nutrient defic 相似文献
8.
9.
10.
Abstract: The development of a teaching package for nurse educators on drug and alcohol problems is described and the contents of its 16 modules outlined. 相似文献