全文获取类型
收费全文 | 488篇 |
免费 | 19篇 |
专业分类
耳鼻咽喉 | 3篇 |
儿科学 | 19篇 |
妇产科学 | 19篇 |
基础医学 | 30篇 |
口腔科学 | 22篇 |
临床医学 | 39篇 |
内科学 | 115篇 |
皮肤病学 | 10篇 |
神经病学 | 46篇 |
特种医学 | 10篇 |
外科学 | 103篇 |
综合类 | 5篇 |
预防医学 | 25篇 |
眼科学 | 17篇 |
药学 | 30篇 |
肿瘤学 | 14篇 |
出版年
2023年 | 3篇 |
2022年 | 3篇 |
2021年 | 13篇 |
2020年 | 3篇 |
2019年 | 5篇 |
2018年 | 6篇 |
2017年 | 11篇 |
2016年 | 12篇 |
2015年 | 23篇 |
2014年 | 16篇 |
2013年 | 14篇 |
2012年 | 31篇 |
2011年 | 32篇 |
2010年 | 12篇 |
2009年 | 14篇 |
2008年 | 19篇 |
2007年 | 28篇 |
2006年 | 39篇 |
2005年 | 41篇 |
2004年 | 37篇 |
2003年 | 36篇 |
2002年 | 29篇 |
2001年 | 19篇 |
2000年 | 9篇 |
1999年 | 9篇 |
1998年 | 3篇 |
1997年 | 3篇 |
1996年 | 2篇 |
1995年 | 2篇 |
1994年 | 3篇 |
1993年 | 2篇 |
1992年 | 6篇 |
1991年 | 6篇 |
1990年 | 3篇 |
1989年 | 1篇 |
1988年 | 3篇 |
1986年 | 2篇 |
1984年 | 2篇 |
1983年 | 1篇 |
1982年 | 1篇 |
1979年 | 1篇 |
1976年 | 2篇 |
排序方式: 共有507条查询结果,搜索用时 109 毫秒
1.
A number of neurotransmitters and neuropeptides in the hypothalamus play a role in the control of food intake, metabolism, and body weight. Particularly, noradrenergic mechanisms in several areas of the hypothalamus are involved. Control of peripheral metabolism by the hypothalamus is achieved via autonomic modulation of the function of hepatocytes, adipocytes, and the endocrine cells in the islets of Langerhans. The autonomic control mechanisms ultimately lead to an appropriate shaping of blood glucose, plasma FFA, and insulin profiles to guarantee an adequate flow of nutrients under different physiological situations. Peripheral insulin and glucose can penetrate into the brain where they might affect the function of those brain structures involved in control of food intake, metabolism, and body weight. 相似文献
2.
3.
Onder Güney Jale Bengi Celik Mehmet Arazi Mehmet Erkan Ustun 《Journal of clinical neuroscience》2004,11(5):517-520
This study aims to evaluate the effects of gamma-hydroxybutyrate (GHB) after spinal cord trauma (SCT). Twenty rabbits were divided equally into four groups: group I was the sham-operated group, group II suffered from SCT but received no treatment, group III was given a dose of 400 mg/kg of GHB intravenously before SCT and group IV received the same dose after SCT. Cerebrospinal fluid (CSF) samples were obtained 30 min before SCT (T(0)), at 60 (T(1)) and 120 min (T(2)) after SCT. There was a threefold increase in lactate levels from baseline value at T(2) in group II, while statistically significant elevation of the lactate levels were not observed in groups III and IV. Glucose levels at T(1) and T(2) were significantly lower in groups III and IV compared with the control group. The findings of this study demonstrate that GHB can control the increase of CSF lactate and glucose levels following SCT and that this metabolic effect may be associated with neuroprotective physiological changes. 相似文献
4.
E Balkan I Kiri?tio?lu A Gürpinar I Ozel K Sinmaz H Do?ruyol 《Archives of disease in childhood》1998,78(3):267-268
The role of sigmoidoscopic examination in the diagnosis, evaluation, and treatment of minor lower gastrointestinal bleeding was investigated. A hundred patients with minor rectal bleeding were examined by rigid sigmoidoscopy under general anaesthesia between January 1989 and July 1996. Patients who had bleeding secondary to infections, anal fissure, or haemorrhoids were excluded from study. Patients were reviewed retrospectively according to their diagnosis and endoscopic and histopathological findings. Twenty nine of these patients were girls and 71 boys; their ages ranged between 8 month and 14 years (mean 7.2 years). Endoscopic pathological findings were established in 60 patients; 32 had rectal polyps, 16 non-specific proctitis, four solitary rectal ulcers, three internal haemorrhoids, two ulcerative colitis, two Hirschsprung's enterocolitis, and one haemangioma. It is concluded that sigmoidoscopic examination should be performed for the diagnosis, prognosis, and choice of treatment in patients with minor rectal bleeding and the diagnosis should be confirmed histopathologically. 相似文献
5.
6.
7.
İbrahim Onur Alici Nilgün Yılmaz Demirci Aydın Yılmaz Funda Demirag Jale Karakaya 《Virchows Archiv : an international journal of pathology》2013,462(3):323-327
We compared the diagnostic performances of conventional smears and cell block preparations of tissue samples obtained with endobronchial ultrasound-guided transbronchial needle aspiration. We retrospectively analysed 451 patients (926 lymph nodes) who had undergone endobronchial ultrasound and for whom both smears and cell blocks were available and compared the diagnostic performances of these techniques when used alone and combined. Cell block preparations showed higher diagnostic performance over smears, but the combination was superior to either alone. The combination of smear and cell block techniques achieved a sensitivity, specificity and positive and negative predictive values of 92.5, 100, 100, 97.7 and 99.4, 95.0, 98.6, and 97.9 % for malignant and benign diseases, respectively. We recommend cell block preparations during endobronchial ultrasound-guided transbronchial needle aspiration. 相似文献
8.
The diagnostic accuracy of ultrasound‐guided fine‐needle aspiration biopsy for thyroid nodules three centimeters or larger in size 下载免费PDF全文
9.
10.