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排序方式: 共有196条查询结果,搜索用时 31 毫秒
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Kazunari Yamaguchi Tsukasa Inaoka Ryutaro Ohtsuka Tomoya Akimichi Tetsuro Hongo Toshio Kawabe Minato Nakazawa Makoto Futatsuka Kiyoshi Takatsuki 《Cancer science》1993,84(7):715-719
Seven hundred and twenty-three serum samples from individuals in 13 Gidra-speaking villages in Western Province, Papua New Guinea were tested for evidence of infection with human T- lymphotropic virus type I (HTLV-I), human immunodeficiency virus type I (HIV-I), hepatitis B virus (HBV) and hepatitis C virus (HCV). No samples were positive for antibodies to HIV-I. Antibodies to HTLV-I were found in 13 samples (1.8%), HBV surface antigens (HBsAg) were found in 86 samples (11.9%), and antibodies to HCV were found in 30 samples (4.1%). Six (46.2%) of 13 HTLV-I positive samples were positive for HCV or HBsAg. The seropositive rate varied in different villages and the incidence of HTLV-I and HCV was higher in coastal and riverine areas than inland. 相似文献
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Mika Tanaka Masahiro Umezaki Kazumi Natsuhara Taro Yamauchi Tsukasa Inaoka Tetsuro Hongo Megumi Nagano Chiho Watanabe Ryutaro Ohtsuka 《American journal of human biology》2005,17(6):696-703
Pacific Islands populations can be broadly divided into Austronesians (AN) and Non-Austronesians (NAN); obesity and type 2 diabetes are prevalent in the former, although leptin levels in both groups have seldom been investigated. Thirty-seven (20 male and 17 female) adult pairs, matched by age and percent body fat, from AN-speaking Balopa and NAN-speaking Huli, all of whom migrated to settle in Port Moresby, the capital of Papua New Guinea, were selected for comparison of their serum leptin concentrations. The Balopa did not differ significantly from the Huli in age (30.5 +/- 9.7 and 30.0 +/- 8.7 years for males, 33.7 +/- 8.9 and 34.1 +/- 7.5 years for females, respectively) or percent body fat (19.4 +/- 5.6 and 18.8 +/- 4.6 for males, 34.1 +/- 6.2 and 33.3 +/- 5.0 for females), although the BMI of females was lower in the Balopa (26.4 +/- 4.9) than in the Huli (29.7 +/- 4.7) (P = 0.02). In both ethnic groups, females had markedly higher leptin concentrations than males, but there was no significant inter-group difference in males (3.5 +/- 2.6 and 3.1 +/- 4.7 ng/ml, P = 0.14) or females (22.7 +/- 12.9 and 19.7 +/- 11.9 ng/ml, P = 0.40), after controlling for lifestyle factors and serum lipids. Multiple regression analysis revealed that significant predictors of leptin concentration were % body fat (beta = 0.58), sex (male, 0; female, 1; beta = 0.27), and smoker status (non-smoker, 0; smoker, 1; beta = -0.15) (R(2) = 0.80), implying that the leptin concentration was primarily determined by lifestyle-derived body fatness. In conclusion, the NAN populations do not endogenously differ in leptin status from the AN populations, who have been recognized as a typical group with a "thrifty" genotype. 相似文献
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Reduced morning cortisol concentration in saliva was associated with obesity: Evidence from community‐dwelling adults in papua new guinea
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8.
Yazawa T Uesaka M Inaoka Y Mizutani T Sekiguchi T Kajitani T Kitano T Umezawa A Miyamoto K 《Endocrinology》2008,149(4):1786-1792
We have shown previously that Cyp11b1, an 11beta-hydroxylase responsible for glucocorticoid biosynthesis in the adrenal gland, was induced by cAMP in androgen-producing Leydig-like cells derived from mesenchymal stem cells. We found that Cyp11b1 was induced in male Leydig cells, or female theca cells, when human chorionic gonadotropin was administered in immature mice. Expression of Cyp11b1 in rodent gonads caused the production of 11-ketotestosterone (11-KT), a major fish androgen, which induces male differentiation or spermatogenesis in fish. As in teleosts, plasma concentrations of 11-KT were elevated in human chorionic gonadotropin-treated mice. In contrast to teleosts, however, plasma concentrations of 11-KT were similar in both sexes, despite levels of testosterone, a precursor substrate, being about 20 times higher in male mice. Because expression of 11beta-hydroxysteroid dehydrogenase type 2, was much higher in the mouse ovary than in the testis, conversion of testosterone into 11-KT may occur more efficiently in the ovary. In a luciferase reporter system that was responsive to and activated by androgens, 11-KT efficiently activated mammalian androgen receptor-mediated transactivation. Our results suggest that the androgen metabolic pathway is conserved between teleosts and mammals, despite sexual dominance and reproductive functions of 11-KT being altered during evolution. 相似文献
9.
Hitoshi Asai Hiroyuki Tsuchiyama Tomoyuki Hatakeyama Pleiades Tiharu Inaoka Kanichirou Murata 《Journal of Physical Therapy Science》2015,27(4):985-988
[Purpose] The purpose of this study was to investigate the relationship between the
ability to perform the sit-to-stand movement and the maximum pelvic anteversion and
retroversion angles of patients. [Subjects] Thirty-two stroke patients (66.7±7.6 years)
(>3 months post-stroke) who were able to sit unsupported and 50 age-matched healthy
subjects participated in this study. The stroke patients were classified into two groups
according to the sit-to-stand movement test: the group that was able to stand up (the
stand-able group) (18 persons) and the group that was unable to stand up (the stand-unable
group) (14 persons). [Methods] Pelvic anteversion and retroversion maximum angles were
measured by a manual goniometer attached to an inclinometer. [Results] The maximum pelvic
anteversion angles were −1.6 ± 5.0°, 1.2 ± 2.8°, and −12.4 ± 6.1° in the control group,
the stand-able stroke group, and the stand-unable stroke group, respectively. A
significant main effect of group was found. An angle discriminating between the two stroke
groups was found: the maximum anteversion angles in the stand-able group were distributed
above −5°. [Conclusion] The maximum pelvic anteversion angle was significantly smaller in
the stand-unable group than in the stand-able and control groups.Key words: Stroke, Pelvis, Sit-to-stand 相似文献
10.
Joweria Nambooze Miho Fujimura Tsukasa Inaoka 《Environmental health and preventive medicine》2014,19(2):143-150