全文获取类型
收费全文 | 5478篇 |
免费 | 460篇 |
国内免费 | 10篇 |
专业分类
耳鼻咽喉 | 61篇 |
儿科学 | 84篇 |
妇产科学 | 66篇 |
基础医学 | 748篇 |
口腔科学 | 157篇 |
临床医学 | 563篇 |
内科学 | 1010篇 |
皮肤病学 | 34篇 |
神经病学 | 455篇 |
特种医学 | 277篇 |
外科学 | 944篇 |
综合类 | 112篇 |
一般理论 | 9篇 |
预防医学 | 417篇 |
眼科学 | 60篇 |
药学 | 650篇 |
中国医学 | 3篇 |
肿瘤学 | 298篇 |
出版年
2022年 | 43篇 |
2021年 | 86篇 |
2020年 | 52篇 |
2019年 | 86篇 |
2018年 | 120篇 |
2017年 | 88篇 |
2016年 | 91篇 |
2015年 | 131篇 |
2014年 | 137篇 |
2013年 | 210篇 |
2012年 | 362篇 |
2011年 | 401篇 |
2010年 | 218篇 |
2009年 | 228篇 |
2008年 | 308篇 |
2007年 | 367篇 |
2006年 | 340篇 |
2005年 | 316篇 |
2004年 | 289篇 |
2003年 | 291篇 |
2002年 | 258篇 |
2001年 | 104篇 |
2000年 | 90篇 |
1999年 | 83篇 |
1998年 | 66篇 |
1997年 | 45篇 |
1996年 | 45篇 |
1995年 | 40篇 |
1994年 | 34篇 |
1993年 | 32篇 |
1992年 | 54篇 |
1991年 | 66篇 |
1990年 | 59篇 |
1989年 | 51篇 |
1988年 | 37篇 |
1987年 | 43篇 |
1986年 | 45篇 |
1985年 | 61篇 |
1984年 | 49篇 |
1983年 | 38篇 |
1982年 | 36篇 |
1980年 | 30篇 |
1979年 | 39篇 |
1978年 | 26篇 |
1977年 | 30篇 |
1976年 | 23篇 |
1975年 | 23篇 |
1974年 | 31篇 |
1973年 | 25篇 |
1970年 | 21篇 |
排序方式: 共有5948条查询结果,搜索用时 421 毫秒
1.
Aim
Tracheomalacia is flaccidity of the tracheal wall leading to tracheal collapse, particularly on expiration. When severe it can warrant surgical intervention. Aortopexy is one surgical option and has been described using a variety of approaches. We report outcomes of aortopexy performed via a suprasternal incision in a single centre by a single surgeon.Methods
All patients undergoing aortopexy between February 2016 and May 2018 were prospectively included. Patients were managed by a multi-disciplinary team (MDT) and underwent standardized work-up, including dynamic flexible bronchoscopy (DFB) and contrast enhanced CT. Aortopexy was performed via a suprasternal skin crease incision. Surgery was guided by intra-operative flexible bronchoscopy. Data regarding pre-operative symptoms, degree of tracheomalacia, and outcomes were recorded.Results
Twenty-two patients were included, 18 boys, median age 5?months (range 1?month–5?years). Two aortopexy sutures were used in all cases, and three patients required an additional tracheopexy suture. Median operating time was 1?h 24?min (range 47?min–2?h 35?min). Median pre-operative tracheal collapse on DFB was 85% (range 80–95%), improving to 35% (35–80%) intra-operatively. Median length of stay was 4?days (range 1–118).Conclusions
Aortopexy via a suprasternal incision is a useful treatment modality for tracheomalacia with short operating times and rapid recovery. Outcomes vary with the best results in the TOF and premature groups. Careful patient selection and MDT work-up are essential to optimize outcomes.Level of Evidence
Level 3 (Case Series). 相似文献2.
3.
4.
5.
6.
Chad G. Ball Andrew W. Kirkpatrick Matthew Smith Robert H. Mulloy Leonard Tse Ian B. Anderson 《European journal of trauma and emergency surgery》2007,33(5):550-552
Abstract We report a case of SMV injury in a critically ill patient. The patient was a 19-year-old woman involved in a motor vehicle
collision. Her injuries included grade II splenic and renal lacerations, devascularized and lacerated right and transverse
colon, a transected transverse mesocolon, a massive shear injury of her abdominal wall, and two partial SMV transections.
At initial damage control laparotomy, the SMV was ligated, the devascularized bowel resected and a temporary abdominal closure
applied. At re-operation, a mesocaval shunt using saphenous vein was employed. The shunt failed and the patient required a
saphenous vein jump graft. Although visceral vascular injuries are rare, ligation of the SMV in a damage control situation
is acceptable. This case study is the first to discuss appropriate treatment when interruption to a patient's collateral visceral
venous drainage limits the surgeon’s ability to ligate. In these situations, bypass shunts may be successful. 相似文献
7.
Tass H Malik Iain A Bruce Gerard Kelly Richard T Ramsden Shakeel R Saeed 《Skull base》2007,17(4):235-238
In cases of cerebrospinal fluid (CSF) rhinorrhea following lateral skull base surgery, fibrosis and fibrin formation resulting from meningitis has been postulated as a mechanism of spontaneously resolving the CSF leak. This study was undertaken to explore any possible relationship between the cessation of CSF leak and meningitis. A retrospective study at a tertiary referral center of 232 consecutive patients was performed. Out of a total of 232 procedures, 29 patients developed CSF rhinorrhea, of whom 7 subsequently developed meningitis. Bacteria were isolated in CSF obtained at lumbar puncture in 5 cases, with the CSF analysis in the remaining 2 cases suggesting aseptic meningitis. Conservative treatment failed to stop the CSF rhinorrhea in 6 of 7 cases. In this study, the development of meningitis did not appear to aid in the resolution of the CSF rhinorrhea. We conclude that surgical intervention should not be delayed in the expectation that meningitis and conservative interventions may promote CSF leak resolution. 相似文献
8.
9.
10.
PLASMA FOLLISTATIN CONCENTRATIONS INCREASE FOLLOWING LIPOPOLYSACCHARIDE ADMINISTRATION IN SHEEP 总被引:1,自引:0,他引:1
Rudi Klein Iain J. Clarke† Mark P. Hedger† David M. Robertson† 《Clinical and experimental pharmacology & physiology》1996,23(8):754-755
1. The effect of inflammation induced by lipopolysaccharide (LPS) injection on plasma follistatin (FS) concentrations was investigated. 2. Plasma FS and tumour necrosis factor-α concentrations increase following LPS administration in ewes. 3. The rise in FS is similar, but more sustained, to that previously observed after surgery. 4. These results indicate a possible functional link between FS, inflammation and the acute-phase response. 相似文献