全文获取类型
收费全文 | 2732篇 |
免费 | 157篇 |
国内免费 | 25篇 |
专业分类
耳鼻咽喉 | 8篇 |
儿科学 | 167篇 |
妇产科学 | 40篇 |
基础医学 | 384篇 |
口腔科学 | 197篇 |
临床医学 | 220篇 |
内科学 | 593篇 |
皮肤病学 | 29篇 |
神经病学 | 95篇 |
特种医学 | 484篇 |
外科学 | 245篇 |
综合类 | 32篇 |
一般理论 | 1篇 |
预防医学 | 104篇 |
眼科学 | 33篇 |
药学 | 158篇 |
中国医学 | 23篇 |
肿瘤学 | 101篇 |
出版年
2023年 | 6篇 |
2022年 | 25篇 |
2021年 | 45篇 |
2020年 | 27篇 |
2019年 | 38篇 |
2018年 | 57篇 |
2017年 | 24篇 |
2016年 | 50篇 |
2015年 | 59篇 |
2014年 | 70篇 |
2013年 | 117篇 |
2012年 | 104篇 |
2011年 | 101篇 |
2010年 | 134篇 |
2009年 | 105篇 |
2008年 | 91篇 |
2007年 | 91篇 |
2006年 | 90篇 |
2005年 | 64篇 |
2004年 | 69篇 |
2003年 | 64篇 |
2002年 | 47篇 |
2001年 | 37篇 |
2000年 | 59篇 |
1999年 | 35篇 |
1998年 | 138篇 |
1997年 | 121篇 |
1996年 | 129篇 |
1995年 | 95篇 |
1994年 | 81篇 |
1993年 | 82篇 |
1992年 | 35篇 |
1991年 | 32篇 |
1990年 | 21篇 |
1989年 | 61篇 |
1988年 | 49篇 |
1987年 | 53篇 |
1986年 | 53篇 |
1985年 | 47篇 |
1984年 | 25篇 |
1983年 | 33篇 |
1982年 | 35篇 |
1981年 | 22篇 |
1980年 | 36篇 |
1979年 | 16篇 |
1978年 | 16篇 |
1977年 | 19篇 |
1976年 | 28篇 |
1975年 | 29篇 |
1971年 | 5篇 |
排序方式: 共有2914条查询结果,搜索用时 78 毫秒
1.
Paula Vanessa Pedron Oltramari Ricardo de Lima Navarro José Fernando Castanha Henriques Rumio Taga Tania Mary Cestari Guilherme Janson José Mauro Granjeiro 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(5):e9-16
OBJECTIVE: The objective of this study was to radiographically quantify bone density and bone height preservation in tooth extraction alveolus filled with xenograft. STUDY DESIGN: The maxillary and mandibular fourth deciduous molars and fourth premolars of 6 minipigs were removed. Randomly, in 3 animals the right side was used as the test side and in the other 3 animals the left side was the test side. Intraoral radiographs were performed to compare the condition at the initial time and 3 months later. Measurements of bone height and bone density were performed using KS300 (Zeiss) software. RESULTS: After 3 months, there was a statistically significant smaller bone height loss for the test group. The test group presented a statistically greater bone density immediately after tooth extraction. However, after 3 months there was no statistically significant difference between the groups. CONCLUSIONS: The results suggest that treatment of postextraction alveolus with xenograft can preserve bone height initially but differences in bone density compared to when no xenograft is used are not sustained. 相似文献
2.
JA HYEON KU CHEOL KWAK SEUNG-JUNE OH EUNSIK LEE SANG EUN LEE JAE-SEUNG PAICK 《International journal of urology》2004,11(7):489-493
BACKGROUND: Our aims in the present study were to estimate the influences of pain and urinary symptoms on quality of life, and to determine which of these two variables has the most predictive power with respect to quality of life in young men with chronic prostatitis-like symptoms. METHODS: Chronic prostatitis-like symptoms were measured by the National Institutes of Health-Chronic Prostatitis Symptom Index. Of the 28,841 men aged 20 years who lived in the study community, 18,495 men (a response rate 64.1%) agreed to participate in the study. A total of 1057 men who complained of symptoms indicative of chronic prostatitis were included in the study. The influences of pain and urinary symptoms on quality of life were determined using logistic regression analysis. The receiver operating characteristic (ROC) curve was used to estimate the predictive ability of each of these variables with respect to quality of life. RESULTS: Results from multivariate analysis showed that both pain and urinary symptoms were associated with an increased likelihood of impaired quality of life, although pain contributed more to a reduced quality of life than urinary symptoms. Relative to men who experienced mild pain, men who experienced moderate pain had a 3.9-fold risk of poor quality of life (odds ratio [OR], 3.87; 95% confidence interval [CI], 2.86-5.23; P < 0.001) and those who experienced severe pain had a 15.7-fold risk of reduced quality of life (OR, 15.68; 95% CI, 6.59-37.35; P < 0.001). Moderate urinary symptoms were associated with a 1.4-fold risk of bother (OR, 1.41; 95% CI, 1.01-1.99; P < 0.001) and severe urinary symptoms were associated with 2.4-fold risk (OR, 2.39; 95% CI, 1.37-4.12; P < 0.001), relative to mild urinary symptoms. Comparison of the effects of pain and urinary symptoms showed that pain severity had the most predictive power for bother, quality of life, and quality-of-life impact. The areas under the ROC curves for bother, quality of life, and quality-of-life impact were 71.3%, 69.3% and 72.5%, respectively. CONCLUSION: Urinary symptoms and pain might be associated with an increased likelihood of impaired quality of life in young men with chronic prostatitis-like symptoms. In addition, our findings suggest that pain severity is the most influential variable for determining quality of life in this population. 相似文献
3.
4.
5.
6.
7.
8.
F. Veiga Fernandes J. Coutinho M. P. Henriques B. da Silva A. Baptista A. I. Santos F. Godinho 《Transplant international》1992,5(Z1):S193-S195
A new technique of choledochoenterostomy was devised to solve some of the problems of enterobiliary anastomosis with a normal calibre. The distal extremity of the common bile duct is completely surrounded by the bowel mucosa to a length of 3 cm after seromyectomy of a bowel wall rectangle of 4 × 1 cm. Experimental studies in rats and dogs demonstrated that this procedure prevents the risks of anastomotic disruption and functions like a mechanical unidirectional valve, which has great efficacy in stopping enterobiliary reflux. Studies in ten patients with obstructive jaundice with an extrahepatic biliary dilation less than 1.2 cm diameter submitted to this procedure Confirmed the experimental results. All patients were asymptomatic, without jaundice and with normalization of the liver enzymes after 2 months. The permeability of the valvular anastomosis studied by cholangiography, the HIDA 99mTc test and manometry was quite similar to other classical biliary-enteric anastomosis. In contrast, anti-reflux efficacy was only demonstrated in patients with a valvular anastomosis. 相似文献
9.
Therapy of post-renal transplantation hyperlipidaemia: comparative study with simvastatin and fish oil 总被引:1,自引:0,他引:1
Castro R; Queiros J; Fonseca I; Pimentel J; Henriques A; Sarmento A; Guimaraes S; Pereira M 《Nephrology, dialysis, transplantation》1997,12(10):2140-2143
Background: Recipients of renal transplantation (RT)
exhibit disturbances of serum lipids and apoproteins that may contribute to
their cardiovascular morbidity and mortality. In our renal transplant
department the hypercholesterolaemia prevalence at the first and fifth year
of RT is 70.0% and 81.2%, respectively. Lipid-lowering therapy has been
utilized in many Transplant Units. The aim of our study was to evaluate
post-RT hyperlipidaemia control with simvastatin or fish oil.
Method: Forty-three RT patients (26 men and 17 women)
with persistent hypercholesterolaemia and stable graft function which were
resistant to a lipid-lowering diet (American Heart Association Step Two)
were randomized into two groups and treated for 3 months with simvastatin
(S) (10 mg/day; n=25) and fish oil (F) (6 g/day; n=18). Total cholesterol
(TC), LDL-cholesterol (LDL-C), HDL-cholesterol (HDL-C), lipoprotein a
(Lp(a)), apolipoprotein A1 (Apo A1), and apolipoprotein B (Apo B) were
monitored and at the study baseline they were similar between the two
groups. Results: No side effects were detected after 3
months of therapy. In group S, the concentrations of TC (271±46
mg% vs 228±49mg%; P <0.001), TG (180±78 vs
134±45; P<0.01), LDL-C (177& plusmn;40 vs
144±43; P <0.01) and Apo B (96±18 vs
82±16; P <0.001) were significantly reduced, and Apo A1
concentration had increased (135±24 vs 149±30; P
<0.01). In group F, the concentrations of TC (266±25 vs
240±31; P <0.001), TG (203±105 vs
156±72; P=0.02) and HDL-C (63±15 vs 53±12;
P <0.01) were significantly reduced.
Conclusion: We concluded that low-dose simvastatin and
fish oil are both effective and safe in correcting post-RT hyperlipidaemia.
Further prospective studies with larger follow-up are needed to clarify
whether this therapy has an impact on cardiovascular morbidity and
mortality in RT patients. 相似文献
10.
C U Henriques P Damm A Tabor H Goldstein L M?lsted-Pedersen 《Acta obstetricia et gynecologica Scandinavica》1991,70(4-5):295-297
In order to screen for fetal neural tube defects and chromosome abnormalities, amniocentesis was carried out in 334 women with insulin-dependent diabetes mellitus (IDDM) between 1979 and 1987. Two cases (0.6%; 95% confidence limits 0.1-2.2%) of fetal chromosome abnormality were found: one case of Klinefelter's syndrome and one case of de novo translocation. This is comparable to the overall incidence of chromosome abnormality found at birth and is also comparable to the incidence of fetal chromosome abnormality (1.0%) found by amniocentesis at our Department in a group of 2,264 young non-diabetic women with little risk of contracting genetic disorders. The results suggest that maternal IDDM does not increase the risk of fetal chromosome abnormality and consequently screening by amniocentesis for chromosome abnormalities among diabetic women does not seem to be indicated. 相似文献