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排序方式: 共有1860条查询结果,搜索用时 140 毫秒
1.
Molnár B. Aroca S. Dobos A. Orbán K. Szabó J. Windisch P. Stähli A. Sculean A. 《Clinical oral investigations》2022,26(12):7135-7142
Clinical Oral Investigations - To evaluate t he long-term outcomes following treatment of RT 1 multiple adjacent gingival recessions (MAGR) using the modified coronally advanced tunnel (MCAT) with... 相似文献
2.
Dr. Gustav Pickroth 《Langenbeck's archives of surgery / Deutsche Gesellschaft fur Chirurgie》1949,262(5-6):385-389
Zusammenfassung Als Beitrag zur Frage eines Überganges der Cystenmamma in Carcinom werden in der vorliegenden Arbeit 381 Fälle mit klinisch einwandfrei cystischen Veränderungen der Brustdrüse aus der Chirurgischen Universitätsklinik Jena der Jahre 1920–1946 zusammengestellt unddie histologisch bewiesenen Fälle (169) zu Besprechungen herangezogen. Dabei zeigte sich, daßin 7,1% der Fälle die Mastopathia cystica einenKrebs oder krebsartige Veränderungen aufweist. Nach diesem Häufigkeitsverhältnis können wir diese Erkrankung nicht als Präcarcinomatose oder als Erkrankung, auf deren Boden sich ein Krebs prädisponiert entwickelt, ansprechen. Die Tatsache aber allein der Krebsentwicklung mahnt zur Vorsicht und weist die damit sich ergebende Behandlung, die kurz aufgezeichnet wird. Nachuntersuchungen und Anfragen bestätigen das gefundene Ergebnis. 相似文献
3.
Dr. Gustav Paul 《Archives of dermatological research》1900,52(1):3-28
Ohne ZusammenfassungHiezu Taf. I–V. 相似文献
4.
Ohne ZusammenfassungHierzu Taf. I–III.Anmerkung des Herausgebers. Diese Abhandlung ist vor dem Erscheinen der neuesten Schrift des Herrn v. Luschka über den Schlundkopf eingesendet worden. 相似文献
5.
Ohne Zusammenfassung 相似文献
6.
Dr. Gustav Behrend 《Virchows Archiv : an international journal of pathology》1872,55(3-4):538-538
Ohne Zusammenfassung 相似文献
7.
Paul S. Malchesky Rolf Bambauer Takashi Horiuchi† DAndre Kaplan‡ Yutaka Sakurada§ Gustav Samuelsson& 《Artificial organs》1995,19(4):315-323
Abstract: The developments in apheresis techniques and their clinical applications world-wide are technologically driven. In the past, apheresis survey statistics have highlighted both the differences by region in clinical practice and in the types of technologies utilized. Such differences have provided a basis for the scientific and clinical assessments of these apheresis technologies and their clinical outcomes and have stimulated the marketing and business development of new technologies world-wide. A review of the regional practices and technologies utilized provides a perspective on the future role of apheresis and its developments in clinical practice. While technology is a driving force for the development of new techniques for clinical practice, it is not the only market force. For technology introduction, several other important issues need to be considered. Regulations at the local and, most importantly, the federal level impact the timing for new technology introduction. Reimbursement by healthcare payers is critically important from the initiation of the development of a technology through its clinical use. Clinical trials are critically important to show the safety and clinical- and cost-effectiveness of the technology in order for payers to provide reimbursement for its use, but these trials are sometimes long and costly. Research funding availability at the governmental and commercial levels critically impacts new technology investigation and its introduction. Apheresis technology developments offer new hopes and promises for the clinical team; however, their development, introduction, and utilization will be influenced by the prevailing market forces. 相似文献
8.
Thirty primary gastrointestinal non-Hodgkin's lymphoma treated between 1983-1990 were reviewed to reveal the efficacy of various treatment strategies. The average age at the diagnosis 53.6 (18-76) years. The histologic material were evaluated according to the Kiel classification: 22 patients had high grade malignant lymphoma (centroblastoma 8, immunoblastoma 6, lymphoblastoma 2, non classifiable 5, T-cell lymphoma 1) 8 patients low grade malignant lymphoma (lymphocytic 2, immunocytic 2, MALT lymphoma 1, centrocytoma 1, non-classifiable 1, pleomorph small cell lymphoma 1). 21 were primary gastric lymphoma, 5 involved the small intestine, 2 the ileocecal region, and 2 the large intestine. According to the Ann Arbor staging system 7 patients were stage I/E, 16 patients stage II/E, 5 patients stage III/E and 2 patients stage IV/E. Every patients underwent surgical resection. After surgical treatment high grade malignancies were treated with ProMACE-COPP (9) and CHOP-Bleo (10) polychemotherapy; low grade malignancies received VEP (5) and CVP (3) chemotherapy. 23 of 30 patients achived complete remission. The patients with low grade malignancy are in remission. All but one patients with high grade malignant gastric lymphoma achieved complete remission with a median of 37 (3-81) months relapse-free survival. Out of 5 cases in the small intestine only in 1 case was remission achieved. Histological type (Kiel) and surgical resection were the most important prognostic factors. 相似文献
9.
Expression of cell-matrix molecules and integrin receptors in human liver grafts during chronic rejection 总被引:1,自引:0,他引:1
Ken Hoshino Bjorn Nashan Gustav Steinhoff Rudolf Pichlmayr K. Hoshino 《Transplant international》1994,7(S1):637-640
Abstract The inflammatory response of immune cells to target cells and cell-matrix molecules is regulated by several receptor-ligand molecules. As fibrosis develops in ongoing chronic rejection after liver transplantation, it is of interest to analyze patterns of integrin receptors and cell-matrix molecules in order to study the relation between immune cells and the stromal and parenchymal cells. In the present study, we demonstrated the expression of these molecules in chronic rejected human liver grafts using immunohistochemical techniques. The results showed a differential expression and induction of integrin receptors and cell-matrix molecules on resident liver cells, especially on sinusoids, reflecting a state of chronic inflammation and a specific interaction between integrin receptors and cell-matrix molecules. The patterns of induced integrin receptors on graft-infiltrating cells was closely related to the local production of cell-matrix molecules and reflected the final sequence of a stepwise progress of the inflammatory reaction. 相似文献
10.
Improved cytosolic free calcium mobilization and superoxide production in bicarbonate-based peritoneal dialysis solution 总被引:1,自引:0,他引:1
Dobos G; Burger M; Kuhlmann J; Passlick-Deetjen J; Schollmeyer P; Bohler J 《Nephrology, dialysis, transplantation》1997,12(5):973-977
Background. Intraperitoneal phagocytes play an
important role in local host defence to prevent CAPD peritonitis. The
intracellular calcium [Ca2+]i is thought to be
involved in the regulation of various cell functions. This study therefore
investigates the effect of lactate-based dialysis solution (LBDS) and
bicarbonate-based dialysis solution (BBDS) on cytosolic free calcium
mobilization and superoxide production (SP) as important steps in signal
transduction and bacterial killing. Methods. We
studied changes in [Ca2+]i and SP following
stimulation with N-formyl-methionyl-leucyl-phenylalanine (fMLP) in
polymorphonuclear neutrophils (PMNs) incubated in either LBDS-pH 5.2, LBDS
adjusted to pH 7.4, 1:10 diluted spent and fresh LBDS or BBDS-pH 7.4 with
different glucose concentrations, comparing the data with cells treated
with Hanks buffer (HBSS) pH 7.4 as control. To elucidate the effect of
glucose and lactate PMNs were additionally incubated in HBSS-pH 7.4,
containing glucose (HBSS-Glu-pH 7.4) or lactate (HBSS-Lact-pH 7.4) in the
same concentrations as contained in CAPD solutions and tested as above.
PMNs were isolated from healthy blood donors and incubated with dialysis
solution 10 min prior to stimulation with fMLP.
Results. [Ca2+]i mobilization
and SP were completely inhibited in PMNs incubated in LBDS pH 5.2. pH
adjustment of LBDS to 7.4 and 1:10 dilution of spent and fresh LBDS
corrected some of the suppression of the calcium influx and superoxide
production. BBDS pH 7.4, however, preserved physiological cell function
significantly better at low (1.5 and 2.3%) glucose concentrations.
Conclusion. In comparison to conventional
lactate-based dialysis solution, pH adjusted and 1:10 diluted LBDS,
bicarbonate-based dialysis solution is more biocompatible since it
preserves significantly better neutrophil cell functions. 相似文献