Liver microsomal cytochrome: P-450p and P-450h activity and blood corticosteroid levels of experimental animals exposed to physical factors

Laboratory of Experimental Therapy, Institute of Balneology, Ministry of Health of the Ukraine, Odessa. Department of Cell Physiology and Pathology, Institute of Clinical and Experimental Medicine, Siberian Branch, Academy of Medical Sciences, Novosibirsk. (Presented by Academician of the Academy of Medical Sciences V. Ya. Kaznacheev.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 113, No. 5, pp. 498–500, May, 1992.     

Stimulation of Diethylnitrosamine Metabolism Reduces Its General Toxic and Hepatocarcinogenic Effects

Bulletin of Experimental Biology and Medicine - The general toxic and hepatocarcinogenic effects of diethylnitrosamine after stimulation of its metabolism with...     

Functional Activity of P-Glycoprotein in Lymphocytes of Patients with Lymphoproliferative Diseases

Functional activity of P-glycoprotein in lymphocytes of patients with lymphoproliferative diseases was studied using rhodamine 123. Functional activity of P-glycoprotein in patients receiving a course of chemotherapy was lower than in controls. P-glycoprotein activity was higher in patients receiving more aggressive therapy. Initially activity of P-glycoprotein was higher in patients who did not respond to chemotherapy in comparison with those whose clinical status improved after a course of chemotherapy.     

Induction of cytochrome P-450 isozymes during long-term nifedipine administration

Department of Cell Physiology and Pathology, Institute of Clinical and Experimental Medicine, Siberian Branch, Academy of Medical Sciences of the USSR, Novosibirsk. Department of Drug Toxicology, Institute of Physiology, Bulgarian Academy of Sciences, Sofia. (Presented by Academician of the Academy of Medical Sciences of the USSR V. P. Kaznacheev.) Translated from Byulleten' Éksperimental'noi Biologi i Meditsiny, Vol. 109, No. 2, pp. 148–150, February, 1990.