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排序方式: 共有229条查询结果,搜索用时 15 毫秒
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Brizzi V Francioli M Brufani M Filocamo L Bruni G Massarelli P 《Il Farmaco; edizione pratica》1999,54(11-12):713-720
The synthesis of a new series of sesamol derivatives with beta-adrenergic blocking activity is described. The affinity and selectivity of these compounds for beta 1- and beta 2-adrenoceptors were studied in comparison with those of ICI-118551 and propranolol. Some of the synthesized compounds show very good affinity for the beta 2-receptors of rat lung membranes and two of them provide interesting selectivity. 相似文献
3.
Rectal endometrial stromal sarcoma arising in endometriosis 总被引:3,自引:0,他引:3
Bosincu L Massarelli G Cossu Rocca P Isaac MA Nogales FF 《Diseases of the colon and rectum》2001,44(6):890-892
PURPOSE: Endometriosis of the rectovaginal septum can harbor different types of secondary tumors that may involve the rectal wall and protrude into its lumen, thus making diagnosis difficult. Extrauterine low-grade endometrial stromal sarcoma may rarely arise in endometriosis. The purpose of this article was to present the third case of this association. METHOD: This was a clinicopathologic study. RESULTS: A 42-year-old female presented with abdominal pain and fever. Laparotomy revealed a large pelvic mass involving the rectovaginal septum and the colonic wall and which protruded into the lumen forming endoluminal polypoid masses. Concomitant peritoneal nodules and a metastatic paracolic lymph node were also found. Histopathologically, primary endometriotic foci were found in close relationship with an endometrial stromal sarcoma which invaded the rectal wall. The female genital tract had no endometriotic lesions. The patient was treated by surgery and subsequent chemotherapy and was alive and well 20 months later. CONCLUSIONS: Endometriosis and its possible malignant changes should be taken into account in the differential endoscopic diagnosis of rectal masses in females. 相似文献
4.
Romagnolo Alberto Balestrino Roberta Imbalzano Gabriele Ciccone Giovannino Riccardini Franco Artusi Carlo Alberto Bozzali Marco Ferrero Bruno Montalenti Elisa Montanaro Elisa Rizzone Mario Giorgio Vaula Giovanna Zibetti Maurizio Lopiano Leonardo 《Journal of neurology》2021,268(3):762-769
Journal of Neurology - Neurological symptoms of COVID-19 patients have been recently described. However, no comprehensive data have been reported on pre-existing neurological comorbidities and... 相似文献
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De Riu G Meloni SM Pisano M Massarelli O Tullio A 《The British journal of oral & maxillofacial surgery》2012,50(1):30-35
The fibular free flap, with or without a cutaneous component, is the gold standard for reconstructing mandibular defects. Dental prosthetic rehabilitation is possible this way, even if the prosthesis-based implant is still a challenge because of the many anatomical and prosthetic problems. We think that complications can be overcome or reduced by adopting the new methods of computed tomography (CT)-assisted implant surgery (NobelGuide, Nobel Biocare AB, Goteborg, Sweden). Here we describe the possibility of using CT-guided implant surgery with a flapless approach and immediate loading in mandibles reconstructed with fibular free flaps. 相似文献
7.
Synthesis and In Vitro Pharmacological Evaluation of Novel 2‐Hydroxypropyl‐4‐arylpiperazine Derivatives as Serotoninergic Ligands 下载免费PDF全文
8.
Ponzetto M Maero B Maina P Rosato R Ciccone G Merletti F Rubenstein LZ Fabris F 《The journals of gerontology. Series A, Biological sciences and medical sciences》2003,58(11):1049-1054
BACKGROUND: Prognostic information collected at hospital admission may be useful in defining care objectives and in deciding on therapy for older people. The aim of our study was to identify admission risk factors for in-hospital and postdischarge mortality. METHODS: The study included 987 patients aged 70 years and older admitted to the geriatric ward of San Giovanni Battista Hospital in Torino during 1995 and 1996. Demographic, clinical, and functional variables were collected on admission to hospital and examined as potential risk factors for mortality during hospitalization and at 5 years of follow-up. RESULTS: During their hospital stay, 147 patients (14.9%) died. Risk factors independently associated with in-hospital mortality included functional impairment (Activities of Daily Living [ADL]) (OR [odds ratio] 1.73, CI [confidence interval] 95% 1.02-2.95), dependence related to medical conditions (OR 2.18, CI 95% 1.39-3.42), cerebrovascular disease (OR 3.23, CI 95% 1.64-6.37), cancer (OR 4.52, CI 95% 1.99-10.24), albumin 3.0-3.4 g/dl (OR 4.51, CI 95% 2.76-7.35), albumin <3.0 g/dl (OR 6.83, CI 95% 3.59-13.0), creatinine 1.5-3 mg/dl (OR 2.23, CI 95% 1.36-3.65), creatinine >3 mg/dl (OR 2.55, CI 95% 1.10-5.93), and fibrinogen >/=452 mg/dl (OR 1.91, CI 95% 1.26-2.89). During the 5-year follow-up, 553 patients (67.7%) died. Variables independently associated with mortality in multivariate analysis were age 75-84 years (HR [hazard ratio] 1.40, CI 95% 1.10-1.78), >/=85 years (HR 2.08, CI 95% 1.59-2.72), male sex (HR 1.50, CI 95% 1.24-1.81), ADL dependency (HR 1.24, CI 95% 1.01-1.52), >/=5 errors on Short Portable Mental Status Questionnaire (HR 1.34, CI 95% 1.10-1.63), dependence on Dependence Medical Index (HR 1.36, CI 95% 1.10-1.67), presence of cancer (HR 2.58, CI 95% 1.80-3.71), hemoglobin =11 g/dl (HR 1.46, CI 95% 1.17-1.81), and Charlson's Index >/=2 (HR 1.49, CI 95% 1.14-1.95). CONCLUSIONS: A complete functional and clinical evaluation at hospital admission permits identification of patients at higher risk of early and long-term mortality. 相似文献
9.
Lucio Boglione Silvia Corcione Nour Shbaklo Tiziana Rosso Tommaso Lupia Simone Mornese Pinna Silvia Scabini Giovannino Ciccone Ilaria De Benedetto Silvio Borr Francesco Giuseppe De Rosa 《Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive》2022,30(1):80
10.
Multi-unit activity recorded from two electrodes positioned at a distance on a nerve may be analysed by cross-correlation, but units similar in direction and velocity of propagation cannot be distinguished and separately evaluated by this method. To overcome this limit, we added two features, represented by the impulse amplitudes of the paired recordings, to the dimension given by the impulse delay. The analysis was fractionated according to the new dimensions. In experimental recordings from the locomotor appendage of the lobster Homarus americanus, the fractionated analysis proved capable of identifying the contributions of single active units, even if these were superimposed and indiscernible in the global cross-correlation histogram. Up to 5 motor and 10 sensory units could be identified. The shape of the paired impulses was evaluated by an averaging procedure. Analogous evaluations on simulated recordings made it possible to estimate the influences exerted on performance by variations in noise level and in the number and firing rate of active units. The global signal could be resolved into single units even under the worst conditions. Accuracy in evaluating the amount of unit activity varied, exceeding 90% in about half of the cases tested; a similar performance was attained by evaluation of the impulse shapes. 相似文献