全文获取类型
收费全文 | 32349篇 |
免费 | 1874篇 |
国内免费 | 112篇 |
专业分类
耳鼻咽喉 | 470篇 |
儿科学 | 1262篇 |
妇产科学 | 964篇 |
基础医学 | 5332篇 |
口腔科学 | 926篇 |
临床医学 | 2612篇 |
内科学 | 6667篇 |
皮肤病学 | 722篇 |
神经病学 | 3125篇 |
特种医学 | 1176篇 |
外国民族医学 | 14篇 |
外科学 | 4326篇 |
综合类 | 163篇 |
一般理论 | 5篇 |
预防医学 | 1883篇 |
眼科学 | 614篇 |
药学 | 1824篇 |
中国医学 | 68篇 |
肿瘤学 | 2182篇 |
出版年
2023年 | 235篇 |
2022年 | 436篇 |
2021年 | 711篇 |
2020年 | 440篇 |
2019年 | 604篇 |
2018年 | 686篇 |
2017年 | 534篇 |
2016年 | 743篇 |
2015年 | 719篇 |
2014年 | 927篇 |
2013年 | 1176篇 |
2012年 | 1719篇 |
2011年 | 1833篇 |
2010年 | 900篇 |
2009年 | 885篇 |
2008年 | 1515篇 |
2007年 | 1582篇 |
2006年 | 1465篇 |
2005年 | 1497篇 |
2004年 | 1229篇 |
2003年 | 1221篇 |
2002年 | 1094篇 |
2001年 | 927篇 |
2000年 | 957篇 |
1999年 | 811篇 |
1998年 | 390篇 |
1997年 | 291篇 |
1996年 | 232篇 |
1995年 | 212篇 |
1994年 | 192篇 |
1993年 | 188篇 |
1992年 | 490篇 |
1991年 | 515篇 |
1990年 | 491篇 |
1989年 | 408篇 |
1988年 | 388篇 |
1987年 | 405篇 |
1986年 | 395篇 |
1985年 | 394篇 |
1984年 | 276篇 |
1983年 | 216篇 |
1981年 | 149篇 |
1979年 | 269篇 |
1978年 | 186篇 |
1977年 | 157篇 |
1976年 | 152篇 |
1975年 | 167篇 |
1974年 | 196篇 |
1973年 | 167篇 |
1972年 | 154篇 |
排序方式: 共有10000条查询结果,搜索用时 31 毫秒
1.
Mette Nissen Tiina‐Mari Ikheimo Jukka Huttunen Ville Leinonen Henna‐Kaisa Jyrkknen Mikael von und zu Fraunberg 《Neuromodulation》2021,24(1):102-111
ObjectiveSpinal cord stimulation (SCS) is an effective treatment in failed back surgery syndrome (FBSS). We studied the effect of preimplantation opioid use on SCS outcome and the effect of SCS on opioid use during a two-year follow-up period.Materials and methodsThe study cohort included 211 consecutive FBSS patients who underwent an SCS trial from January 1997 to March 2014. Participants were divided into groups, which were as follows: 1) SCS trial only (n = 47), 2) successful SCS (implanted and in use throughout the two-year follow-up period, n = 131), and 3) unsuccessful SCS (implanted but later explanted or revised due to inadequate pain relief, n = 29). Patients who underwent explantation for other reasons (n = 4) were excluded. Opioid purchase data from January 1995 to March 2016 were retrieved from national registries.ResultsHigher preimplantation opioid doses associated with unsuccessful SCS (ROC: AUC = 0.66, p = 0.009), with 35 morphine milligram equivalents (MME)/day as the optimal cutoff value. All opioids were discontinued in 23% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.004). Strong opioids were discontinued in 39% of patients with successful SCS, but in none of the patients with unsuccessful SCS (p = 0.04). Mean opioid dose escalated from 18 ± 4 MME/day to 36 ± 6 MME/day with successful SCS and from 22 ± 8 MME/day to 82 ± 21 MME/day with unsuccessful SCS (p < 0.001).ConclusionsHigher preimplantation opioid doses were associated with SCS failure, suggesting the need for opioid tapering before implantation. With continuous SCS therapy and no explantation or revision due to inadequate pain relief, 39% of FBSS patients discontinued strong opioids, and 23% discontinued all opioids. This indicates that SCS should be considered before detrimental dose escalation. 相似文献
2.
Hommes Franziska Mohsenpour Amir Kropff Dana Pilgram Lisa Matusall Svenja von Philipsborn Peter Sell Kerstin 《Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz》2022,65(1):96-106
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz - Akteure der öffentlichen Gesundheit (Public Health) tragen wesentlich zu Gesundheitsschutz, -förderung und... 相似文献
3.
4.
Toshiro Hara Rony Chanoch-Myers Nathan D. Mathewson Chad Myskiw Lyla Atta Lillian Bussema Stephen W. Eichhorn Alissa C. Greenwald Gabriela S. Kinker Christopher Rodman L. Nicolas Gonzalez Castro Hiroaki Wakimoto Orit Rozenblatt-Rosen Xiaowei Zhuang Jean Fan Tony Hunter Inder M. Verma Kai W. Wucherpfennig Itay Tirosh 《Cancer cell》2021,39(6):779-792.e11
5.
6.
Die Unfallchirurgie - Zur Diagnostik von Schultergelenkerkrankungen wird routinemäßig die Magnetresonanztomographie (MRT) durchgeführt. Diese kann entsprechend der klinischen... 相似文献
7.
8.
9.
Gabriela Perdomo Coral Angelo Alves de Mattos 《Journal canadien de gastroenterologie》2003,17(3):187-190
BACKGROUND/AIMS: Spontaneous bacterial peritonitis (SBP) is an important complication in cirrhotic patients. The aim of the present study was to assess the incidence, predictive factors and prognosis for renal impairment (RI) after SBP in cirrhotic patients from southern Brazil. METHODS: Of the 1030 hospitalizations evaluated, 114 episodes of SBP were diagnosed in 94 patients (mean age 49 years; 76.59% men). SBP diagnosis was established when the ascitic fluid polymorphonuclear cell count was equal to or greater than 250 cells/mm3. Five cases were excluded. The variables assessed as possible predictors of steady or progressive RI were blood urea nitrogen and creatinine levels before the diagnosis of SBP; type of infection, antibiotic prophylaxis, first episode or recurrent SBP, presence of gastrointestinal bleeding and hepatic encephalopathy during hospitalization, SBP resolution, Child-Pugh classification, levels of blood pressure, ascitic fluid and blood polymorphonuclear cell count, bacteriological data (positive and negative ascitic fluid culture), albumin, bilirubin, sodium and prothrombin time at the moment of diagnosis. RESULTS: The incidence of SBP was 11.07%. In 61 (55.96%) episodes, SBP was associated with RI (transient in 57.37%; steady in 19.67%; and progressive in 22.95%). The mortality rate associated with progressive RI was 100%; 58.33% with steady RI; and 2.85% with transient RI. The mortality rate in patients with or without RI was 36.07% and 6.25%, respectively (P<0.001). The level of creatinine (greater than or equal to 1.3mg/dL) before the diagnosis of SBP and the rate of infection resolution were the only predictors of RI in the multivariate analysis. CONCLUSIONS: RI after SBP is a common complication, and indicates a poor prognosis for this infection. High levels of creatinine before infection and the rate of infection resolution are independent predictors of RI. 相似文献
10.