全文获取类型
收费全文 | 1250篇 |
免费 | 70篇 |
国内免费 | 6篇 |
专业分类
儿科学 | 1篇 |
妇产科学 | 1篇 |
基础医学 | 104篇 |
口腔科学 | 23篇 |
临床医学 | 130篇 |
内科学 | 467篇 |
皮肤病学 | 12篇 |
神经病学 | 130篇 |
特种医学 | 43篇 |
外科学 | 127篇 |
综合类 | 5篇 |
预防医学 | 29篇 |
眼科学 | 47篇 |
药学 | 125篇 |
中国医学 | 1篇 |
肿瘤学 | 81篇 |
出版年
2022年 | 9篇 |
2021年 | 15篇 |
2020年 | 10篇 |
2019年 | 8篇 |
2018年 | 18篇 |
2017年 | 13篇 |
2016年 | 17篇 |
2015年 | 17篇 |
2014年 | 17篇 |
2013年 | 30篇 |
2012年 | 41篇 |
2011年 | 36篇 |
2010年 | 33篇 |
2009年 | 19篇 |
2008年 | 46篇 |
2007年 | 39篇 |
2006年 | 55篇 |
2005年 | 56篇 |
2004年 | 61篇 |
2003年 | 43篇 |
2002年 | 48篇 |
2001年 | 53篇 |
2000年 | 67篇 |
1999年 | 64篇 |
1998年 | 28篇 |
1997年 | 22篇 |
1996年 | 21篇 |
1995年 | 19篇 |
1994年 | 16篇 |
1993年 | 16篇 |
1992年 | 36篇 |
1991年 | 41篇 |
1990年 | 59篇 |
1989年 | 48篇 |
1988年 | 39篇 |
1987年 | 30篇 |
1986年 | 36篇 |
1985年 | 14篇 |
1984年 | 7篇 |
1983年 | 5篇 |
1980年 | 5篇 |
1979年 | 6篇 |
1978年 | 4篇 |
1975年 | 5篇 |
1973年 | 5篇 |
1972年 | 4篇 |
1971年 | 12篇 |
1970年 | 7篇 |
1969年 | 4篇 |
1968年 | 4篇 |
排序方式: 共有1326条查询结果,搜索用时 15 毫秒
1.
H Nakane Y Okada S Sadoshima M Fujishima 《Stroke; a journal of cerebral circulation》1991,22(2):272-275
A 70-year-old woman developed left hypoglossal nerve palsy, a right hemiparesis sparing the face, and a typical left Wallenberg's syndrome. These symptoms resulted from a lesion in the left half of the medulla oblongata, suggesting Babinski-Nageotte syndrome, a rare cerebrovascular disease. This is the first case of ischemic infarction in the territory of the left vertebral artery and posterior inferior cerebellar artery demonstrated on magnetic resonance imaging. Severe bilateral lesions of the distal vertebral arteries demonstrated on digital subtraction angiography may have contributed to the development of this syndrome. 相似文献
2.
AIMS: Differential diagnosis of allergic conjunctivitis or dry eye is sometimes very difficult to diagnose by symptoms and clinical examination alone, especially in older patients. It was hypothesised that clinically allergic patients who were serum antigen specific IgE negative were candidates for dry eye. METHODS: Sixty patients were studied prospectively who were clinically diagnosed with allergic conjunctivitis by their itchy sensation and papilla formation of conjunctiva. They consisted of 30 serum antigen specific IgE positive and 30 IgE negative patients, with no significant differences in age. Dry eye examination and serum total IgE were performed on these two groups. RESULTS: No significant differences were seen between the two groups with regard to age (p = 0.76) and sex ratio. The antibody negative group had lower Schirmer's test scores (p = 0.002), lower tear clearance (p = 0.0001), lower tear function index (p = 0.0001), and lower serum total IgE (p = 0.04) than the antibody positive group. CONCLUSION: This study suggests that the evaluation of serum antigen specific IgE and tear dynamics are important for the differential diagnosis of patients with allergic conjunctivitis and dry eye. Clinically diagnosed allergic conjunctivitis with negative serum antigen specific and total IgE can be one form of dry eye. 相似文献
3.
Tetsuhiko Nagao Seizo Sadoshima Takao Ishitsuka Kenji Kusuda Osamu Shiokawa Setsuro Lbayashi Masatoshi Fujishima 《Clinical and experimental pharmacology & physiology》1992,19(7):489-493
1. The effects of acute bilateral superior cervical ganglionectomy on cerebral blood flow and metabolism were investigated in stroke-prone spontaneously hypertensive rats (SHRsp), before and during cerebral ischaemia. 2. The resting cerebral blood flow was comparable between the control and denervated animals. 3. There was no significant difference in cerebral blood flow or concentration of tissue energy metabolites (adenosine triphosphate [ATP], lactate and pyruvate) between the sham-operated control and denervated animals during ischaemia. 4. The results suggest that sympathetic innervation of cerebral vessels originating from superior cervical ganglia may not play a major role in the progression of cerebral ischaemia in SHRsp. 相似文献
4.
S Kakimoto Y Yushita T Sanefuji A Kondo N Fujishima M Kishikawa K Matsumoto 《Hinyokika kiyo. Acta urologica Japonica》1986,32(5):757-763
We report a case of non-hormonal adrenocortical adenoma. The tumor was removed en block with the adrenal gland. The specimen was 5.0 X 4.5 X 3.0 cm, weighed 30 g and was solid. Histologically, this tumor had an oncocytoma-like appearance. However, as there is no concept of oncocytoma in connection with adrenocortical adenoma, this case was diagnosed as adrenocortical adenoma. A case with such histological findings has never been reported. 相似文献
5.
Minoru Yagi Takeshi Mishina Tsukasa Fujishima Kazutoshi Date Hiroshi Saito Nobuo Suzuki 《Surgery today》1997,27(1):84-87
The acute onset of peritoneal signs and shock in a 7year-old boy who had been hit in the epigastrium by a log-seesaw mandated surgical treatment. Enhanced computed tomography (CT) demonstrated complete laceration of the pancreas as well as duodenal injury, and a duodenoduodenostomy with distal pancreaticogastrostomy was subsequently performed. Temporary external drainage of the stomach and distal pancreas led to an uneventful recovery in the early postoperative period. Although the patient's postoperative development was appropriate for his age, the orifice of the distal pancreas spontaneously closed 2.5 years following surgery. We present this report to stress the fact that every effort should be made to preserve the pancreas following abdominal injury in children. 相似文献
6.
7.
The cecal foramen pointer was invented for a Sistrunk median cervical cyst operation. The instrument consists of three elements, namely: The cecal foramen holder, the giraffe shaped connector and the pointer needle. First of all, the cecal foramen is held by the holder which is reconstructed from hemostatic forceps. The one end of the connector is joined to the holder's handle. Then the other end of the connector comes along the patient's chin, in front of the neck. The cyst and mid-portion of the hyoid bone are dissected, followed by coring out of the thyroglossal duct toward the cecal foramen. In the coring out process, the pointer needle is pierced through the tunnel of the connector's opposite end, so that the needle top reaches to the bottom of operative wound. Then the needle shows exactly the direction to the cecal foramen and the distance from the bottom of the wound to the cecal foramen. By using this instrument the operation was successfully performed for a case of a recurrent median cervical cyst with a complete fistula to the cecal foramen. 相似文献
8.
Hemodynamic and volume changes induced by recombinant human erythropoietin (rHuEPO) treatment were investigated in 12 chronic hemodialysis patients with refractory anemia. After rHuEPO administration for 49 to 151 days, hematocrit (Ht) significantly improved from 19.4 +/- 2.3 to 30.1 +/- 1.1% (Mean +/- SD). Mean blood pressure (MBP) increased slightly but significantly from 78.8 +/- 13.2 to 88.9 +/- 16.9 mmHg. Hemodynamically, total peripheral resistance index (TPRI) increased significantly from 1,444 +/- 367 to 2,146 +/- 470 dynes.sec.cm-5.m2, while cardiac index (CI) decreased significantly from 4.49 +/- 0.85 to 3.37 +/- 0.60 l/min/m2. Both pulse rate (PR) and stroke volume index (SVI) also decreased significantly, but blood volume (BV) remained unchanged. Plasma renin activity and plasma norepinephrine decreased significantly. There were positive correlations between the change of MBP and that of CI, and between the change in CI and that of BV, respectively (p less than 0.05 or less). In conclusion the improvement of anemia using rHuEPO is hemodynamically associated with an increase in TPRI and a decrease in CI as well. Blood pressure elevation seems to be caused by an inappropriately minor reduction of CI. The contribution of humoral factors is not suggested. 相似文献
9.
Renal functions were examined in 102 patients with yusho in 1988, Frequencies of proteinuria, microhematuria and history of renal diseases were not different from 20 age-matched controls. The means of blood urea nitrogen, serum creatinine and serum uric acid levels of yusho patients did not differ from those of controls. The levels of serum beta 2-microglobulin and its urinary excretion showed no difference between two groups. Serum concentrations of sodium, potassium, chloride, calcium and phosphorus revealed no abnormality in all patients except for one who had hypophosphatemia. Urinary excretions of phosphorus, however, were significantly higher in yusho patients than in controls. Serum PCB levels, which were still higher in yusho patients, did not correlate with urinary excretions of phosphorus. The mechanism and the clinical significance of this phenomenon remain to be elucidated. 相似文献
10.