全文获取类型
收费全文 | 3462篇 |
免费 | 234篇 |
国内免费 | 17篇 |
专业分类
耳鼻咽喉 | 20篇 |
儿科学 | 97篇 |
妇产科学 | 58篇 |
基础医学 | 446篇 |
口腔科学 | 107篇 |
临床医学 | 257篇 |
内科学 | 902篇 |
皮肤病学 | 72篇 |
神经病学 | 367篇 |
特种医学 | 115篇 |
外科学 | 380篇 |
综合类 | 15篇 |
一般理论 | 1篇 |
预防医学 | 210篇 |
眼科学 | 30篇 |
药学 | 325篇 |
中国医学 | 9篇 |
肿瘤学 | 302篇 |
出版年
2023年 | 33篇 |
2022年 | 68篇 |
2021年 | 145篇 |
2020年 | 68篇 |
2019年 | 102篇 |
2018年 | 117篇 |
2017年 | 91篇 |
2016年 | 106篇 |
2015年 | 122篇 |
2014年 | 152篇 |
2013年 | 163篇 |
2012年 | 267篇 |
2011年 | 265篇 |
2010年 | 135篇 |
2009年 | 112篇 |
2008年 | 211篇 |
2007年 | 208篇 |
2006年 | 197篇 |
2005年 | 174篇 |
2004年 | 182篇 |
2003年 | 159篇 |
2002年 | 129篇 |
2001年 | 42篇 |
2000年 | 47篇 |
1999年 | 37篇 |
1998年 | 30篇 |
1997年 | 29篇 |
1996年 | 20篇 |
1995年 | 15篇 |
1994年 | 16篇 |
1993年 | 11篇 |
1992年 | 27篇 |
1991年 | 26篇 |
1990年 | 18篇 |
1989年 | 25篇 |
1988年 | 24篇 |
1987年 | 12篇 |
1986年 | 21篇 |
1985年 | 12篇 |
1984年 | 9篇 |
1983年 | 9篇 |
1982年 | 9篇 |
1981年 | 8篇 |
1980年 | 5篇 |
1979年 | 4篇 |
1976年 | 5篇 |
1975年 | 6篇 |
1974年 | 6篇 |
1971年 | 5篇 |
1965年 | 4篇 |
排序方式: 共有3713条查询结果,搜索用时 15 毫秒
1.
2.
3.
IgA antiendomysium antibodies in human umbilical cord sections as a screening test in relatives of patients with celiac disease 总被引:1,自引:0,他引:1
M. Bagnasco P. Montagna A. De Alessandri E. Castellano G. P. Pesce R. Gatti 《Allergy》1997,52(10):1017-1021
We performed the serum IgA antiendomysium antibody (EmA) assay by indirect immunofluorescence on human umbilical cord sections in 86 subjects with celiac disease, in 187 first-degree relatives of such patients, and in a control group of 68 unrelated subjects, to investigate the suitability of the method in the screening of populations at risk of gluten sensitivity. Conventional EmA assay using monkey esophagus sections was performed in parallel experiments. The results obtained showed a perfpect correlation between the two methods. All the celiac patients and none of the controls were positive for EmA. EmA positivity was also observed in 11 apparently healthy relatives: intestinal biopsy performed in five of them invariably showed villous atrophy and increase of mucosal lymphocytes. Taking into account the low cost of EmA assay on human umbilical cord, especially when compared to monkey esophagus sections, the method is probably suitable and effective in identifying latent, asymptomatic gluten sensitivity in at-risk populations. 相似文献
4.
5.
I de Sio L Castellano M Calandra C Del Vecchio-Blanco 《European Journal of Ultrasound》2002,15(1-2):65-68
A case of subcutaneous neoplastic seeding after fine needle aspiration biopsy of a pancreatic liver metastasis is reported. Neoplastic seeding is a rare complication after fine needle biopsy (FNB). The seeding appeared 3 months after the biopsy with a subcutaneous hypoechoic nodule; diagnosis was confirmed by fine needle aspiration of the nodule. The neoplastic seeding did not change the outcome of the patient. 相似文献
6.
Antonio Amoroso Pierluigi Garzia Marta Vadacca Sara Galluzzo Flavia Del Porto Anna P Mitterhofer Antonella Afeltra 《The Journal of adolescent health》2003,32(1):94-97
We report on a 26-year-old female affected by Noonan syndrome (NS), a congenital disorder characterized by various phenotypic features and congenital anomalies) associated with a variety of autoimmune diseases, including systemic lupus erythematosus, celiac disease, and Hashimoto thyroiditis. Autoimmunity is seldom described in NS and the association between this congenital disease and three autoimmune disorders has not been previously reported. Should the occurrence of autoimmune disorders in NS be confirmed, a relevant clinical and laboratory evaluation of NS patients should be performed in order to clarify whether the immune system involvement represents only an occasional event or is a feature of the disease. 相似文献
7.
8.
9.
Lucia Carvalho Monica Lipay Francisco Belfort Ivan Santos Joyce Andrade Alessandra Haddad Flavia Brunstein Lydia Ferreira 《Journal of plastic, reconstructive & aesthetic surgery》2006,59(9):961-968
BACKGROUND: Telomerase activity (TA) is believed to play a role in the regulation of senescence and to limit the number of cell divisions. The deregulation of telomerase appears to contribute to oncogenesis and the formation of immortal cell lines. As a result, it is believed that it could be used as a prognostic marker in melanoma. METHODS: TA was assayed by the polymerase chain reaction PCR-ELISA-based telomeric repeat amplification protocol (TRAP assay). One hundred and eight samples were distributed in four histological groups: 30 samples from primary cutaneous melanomas, 24 from peritumoural skin sites, 28 from benign melanocytic lesions, and 26 from normal skin sites as a control. RESULTS: TA was different among the four tested groups (Kruskall-Wallis test p<0.001), and increasing values of TA were observed progressing from normal skin to benign and then to malignant lesions. Among melanoma samples, there was a significant association between TA and ulceration (p=0.025), TA and vascular invasion (p=0.018) and TA and mitotic rate (p=0.029) (Mann-Whitney test). A linear regression analysis showed significant associations between the increase of TA with Breslow thickness (p=0.004) and the presence of satellites (p=0.002). CONCLUSIONS: We observed that TA had increased from control skin to peritumoural skin, and then to benign melanocytic lesions and finally to melanoma, suggesting tumour progression. TA showed higher values in the presence of some important histopathologic parameters related to poor prognosis in cutaneous melanoma such as ulceration, vascular invasion, satellites, high rates of mitosis, and in thicker tumours. 相似文献