全文获取类型
收费全文 | 26585篇 |
免费 | 1788篇 |
国内免费 | 150篇 |
专业分类
耳鼻咽喉 | 316篇 |
儿科学 | 539篇 |
妇产科学 | 553篇 |
基础医学 | 3589篇 |
口腔科学 | 574篇 |
临床医学 | 2908篇 |
内科学 | 5749篇 |
皮肤病学 | 380篇 |
神经病学 | 2606篇 |
特种医学 | 1093篇 |
外国民族医学 | 1篇 |
外科学 | 3305篇 |
综合类 | 249篇 |
一般理论 | 52篇 |
预防医学 | 2645篇 |
眼科学 | 933篇 |
药学 | 1487篇 |
中国医学 | 33篇 |
肿瘤学 | 1511篇 |
出版年
2023年 | 114篇 |
2022年 | 203篇 |
2021年 | 463篇 |
2020年 | 298篇 |
2019年 | 408篇 |
2018年 | 527篇 |
2017年 | 400篇 |
2016年 | 466篇 |
2015年 | 513篇 |
2014年 | 780篇 |
2013年 | 1089篇 |
2012年 | 1531篇 |
2011年 | 1722篇 |
2010年 | 982篇 |
2009年 | 911篇 |
2008年 | 1536篇 |
2007年 | 1576篇 |
2006年 | 1447篇 |
2005年 | 1548篇 |
2004年 | 1405篇 |
2003年 | 1309篇 |
2002年 | 1313篇 |
2001年 | 331篇 |
2000年 | 289篇 |
1999年 | 356篇 |
1998年 | 308篇 |
1997年 | 316篇 |
1996年 | 278篇 |
1995年 | 250篇 |
1994年 | 215篇 |
1993年 | 195篇 |
1992年 | 248篇 |
1991年 | 236篇 |
1990年 | 221篇 |
1989年 | 174篇 |
1988年 | 176篇 |
1987年 | 176篇 |
1986年 | 175篇 |
1985年 | 191篇 |
1984年 | 204篇 |
1983年 | 188篇 |
1982年 | 176篇 |
1981年 | 195篇 |
1980年 | 167篇 |
1979年 | 143篇 |
1978年 | 137篇 |
1977年 | 131篇 |
1975年 | 132篇 |
1974年 | 116篇 |
1973年 | 134篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
3.
4.
5.
Rebecca L. King Albert C. Yan Debora R. Sekiguchi John K. Choi 《Journal of cutaneous pathology》2015,42(12):1012-1017
Reactive lymphoid infiltrates of the skin composed predominantly of gamma‐delta (γδ) T cells are not well described in the literature. Herein we report a case of an otherwise healthy 4‐year‐old male who presented with a waxing and waning papular rash characterized by small, discrete crusted papules spread across his trunk, face and extremities. Clinical evaluation revealed no evidence of systemic disease. Microscopic examination revealed a dermal, perivascular infiltrate of highly atypical lymphocytes with a γδ T cell phenotype, worrisome for primary cutaneous γδ T cell lymphoma. The clinical course, however, was that of a reactive condition and prompted consideration of a diagnosis of pityriasis lichenoides et varioliformis acuta (PLEVA) and lymphomatoid papulosis (LyP). In many ways, this case defies current classification schemes and seems to expand the spectrum of reactive γδ T cell infiltrates of the skin. 相似文献
6.
Tormo Nuria Giménez Estela Martínez-Navarro María Albert Eliseo Navalpotro David Torres Ignacio Gimeno Concepción Navarro David 《European journal of clinical microbiology & infectious diseases》2022,41(4):657-662
European Journal of Clinical Microbiology & Infectious Diseases - We compared the performance of an in-house-developed flow cytometry assay for intracellular cytokine staining (FC-ICS) and a... 相似文献
7.
Jennifer C. Sasaki Ashley Allemang Steven M. Bryce Laura Custer Kerry L. Dearfield Yasmin Dietz Azeddine Elhajouji Patricia A. Escobar Albert J. Fornace Jr Roland Froetschl Sheila Galloway Ulrike Hemmann Giel Hendriks Heng-Hong Li Mirjam Luijten Gladys Ouedraogo Lauren Peel Stefan Pfuhler Daniel J. Roberts Véronique Thybaud Jan van Benthem Carole L. Yauk Maik Schuler 《Environmental and molecular mutagenesis》2020,61(1):114-134
In May 2017, the Health and Environmental Sciences Institute's Genetic Toxicology Technical Committee hosted a workshop to discuss whether mode of action (MOA) investigation is enhanced through the application of the adverse outcome pathway (AOP) framework. As AOPs are a relatively new approach in genetic toxicology, this report describes how AOPs could be harnessed to advance MOA analysis of genotoxicity pathways using five example case studies. Each of these genetic toxicology AOPs proposed for further development includes the relevant molecular initiating events, key events, and adverse outcomes (AOs), identification and/or further development of the appropriate assays to link an agent to these events, and discussion regarding the biological plausibility of the proposed AOP. A key difference between these proposed genetic toxicology AOPs versus traditional AOPs is that the AO is a genetic toxicology endpoint of potential significance in risk characterization, in contrast to an adverse state of an organism or a population. The first two detailed case studies describe provisional AOPs for aurora kinase inhibition and tubulin binding, leading to the common AO of aneuploidy. The remaining three case studies highlight provisional AOPs that lead to chromosome breakage or mutation via indirect DNA interaction (inhibition of topoisomerase II, production of cellular reactive oxygen species, and inhibition of DNA synthesis). These case studies serve as starting points for genotoxicity AOPs that could ultimately be published and utilized by the broader toxicology community and illustrate the practical considerations and evidence required to formalize such AOPs so that they may be applied to genetic toxicity evaluation schemes. Environ. Mol. Mutagen. 61:114–134, 2020. © 2019 Wiley Periodicals, Inc. 相似文献
8.
9.
10.
Albert De Decker Rosalie Fergusson Benjamin Ondruschka Niels Hammer Johann Zwirner 《Clinical anatomy (New York, N.Y.)》2020,33(4):522-529
For 50 years now, sacrospinous ligament fixation (SSLF) has been used to treat pelvic organ prolapse consequent on altered integrity of the pelvic myofascial structures. It is usually performed vaginally, but it has recently been performed laparoscopically through either an anterior or a posterior approach, with the broad ligament as a landmark to differentiate the two. In the present study, these two laparoscopic approaches were assessed using Thiel-embalmed cadavers. The anterior and posterior approaches were compared in terms of the closest distance to anatomical structures at risk, including pelvic viscera, the obturator nerve, and vascular structures. The posterior approach was more often closer to the investigated vessels and the rectum. The obturator nerve and the ureter were close to both the anterior and posterior approaches. The urinary bladder was closer using the anterior approach. From an anatomical standpoint, therefore, the anterior laparoscopic approach for SSLF is more likely to cause injury to the urinary bladder, whereas the posterior approach is more prone to causing rectal and vessel injuries. This study illustrates, from a basic science perspective, the importance of combining fascia research, novel endoscopic or minimally invasive surgical exposures informed by anatomy, and contemporary trends in gynecology in order to improve patient outcomes. Clin. Anat. 33:522–529, 2020. © 2019 Wiley Periodicals, Inc. 相似文献